Chinese medicinal preparation for treating atrophic arthritis

A technology of traditional Chinese medicine preparations and arthritis, which is applied in the direction of anti-inflammatory agents, non-central analgesics, medical preparations containing active ingredients, etc. It can solve the problems of unsatisfactory treatment effects and insufficient understanding of the pathogenesis of damp-heat, toxin and blood stasis, etc. Achieve non-toxic side effects, easy to take, and improve immune function

Inactive Publication Date: 2007-02-14
周娅 +3
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, judging from the clinical literature in recent years, the understanding of this disease is mostly focused on wind, cold, dampness and blood stasis, and the pathogenesis of dampness, heat, toxin and blood stasis in the active stage is insufficient, and the treatment effect is not ideal.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] Example 1. Take Qingfengteng 30g, Daxueteng 15g, honeysuckle 20g, red peony 20g, white peony 30g, Gentiana 10g, Smilax cocos 20g, coix seed 30g, Clematis 10g, dried ginger 6g and Piper cubeb 10g, decoct in water and take , one dose per day, 2 months as a course of treatment. It is effective in the treatment of rheumatoid arthritis.

Embodiment 2

[0033] Example 2. Take Qingfengteng 15g, Daxueteng 10g, Honeysuckle 15g, Chishao 15g, Baishao 15g, Gentiana 10g, Smilax 30g, Coix seed 20g, Clematis 15g, Dried ginger 10g and Piper cubeb 6g, decoct in water and take , one dose per day, 2 months as a course of treatment. It is effective in the treatment of rheumatoid arthritis.

[0034] Clinical Trials:

[0035] For verifying the therapeutic effect of the present invention, in 2002-2005, the present invention has been carried out following clinical trial in Liaocheng People's Hospital, Shandong Province:

[0036] 1. Materials and methods

[0037] 1.1 Diagnostic criteria

[0038] 1.1.1 Western medicine diagnostic criteria

[0039] Refer to the diagnostic criteria revised by the American Rheumatology Association (ARA) in 1987: ①Morning stiffness for at least 1 hour (>6 weeks); ②Swelling of 3 or more joints (>6 weeks); ③Wrist, metacarpophalangeal Swollen joints or proximal fingertip joints (>6 weeks); ④symmetric arthritis (>...

example 1

[0106] Example 1. Zhu Moumou, female, 56 years old, came to Liaocheng People's Hospital on April 21, 2004 for treatment due to multiple joint swelling and pain in limbs for 6 months. Symptoms include swelling and pain in shoulder joints, some interphalangeal joints, and knee joints, burning sensation in the pain, difficulty in holding hands firmly, difficulty in squatting and walking. Less appetite, fullness in the epigastric cavity, and normal bowel movements. Body of the tongue is red, thick and greasy yellow coating, stringy and rapid pulse. Physical examination: the interphalangeal joints of the index finger and middle finger of both hands, and both wrist joints were swollen, tenderness grade 3, swelling grade 2, and skin temperature was high. The movement of the left knee joint was limited, and the floating patella sign (+). The grip strength of both hands is 12KPa / Hg, and the joint function is grade II. 20-meter walk time: 29 seconds. Laboratory tests and inspections...

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PUM

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Abstract

A Chinese medicine for treating rheumatoid arthritis is prepared from 11 Chinese-medicinal materials including honeysuckle flower, red peony root, China root, coix seed, etc.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicines, in particular to a traditional Chinese medicine preparation made of pure Chinese medicines for treating rheumatoid arthritis. Background technique [0002] Rheumatoid arthritis is a common chronic, inflammatory, systemic autoimmune disease, and its prevalence rate ranks first among autoimmune connective tissue diseases. The disease has a high morbidity rate, and the main clinical manifestations are symmetrical and progressive polyarthritis, pain, swelling, and functional decline in the affected joints, and the lesions are continuous and recurrent. The pathological manifestations are chronic inflammation of the synovial membrane, which invades articular cartilage, subchondral bone, ligaments and tendons, etc., eventually leading to bone erosion, joint deformity and loss of function. The etiology and pathogenesis of the disease is still unclear in modern medicine, and non-steroidal ant...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/9068A61K36/899A61K36/896A61K36/716A61K36/71A61K36/59A61K36/54A61K36/51A61K36/35A61K36/185A61P29/00A61P19/02
Inventor 周娅张梅红樊敏华董风仙
Owner 周娅
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