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Mite allergen specific yolk immunoglobulin antibody and anti-allergic preparation thereof

An allergen and specific technology, applied in the direction of egg immunoglobulin, anti-animal/human immunoglobulin, antibody, etc., can solve the problems of low patient compliance and high cost, and achieve a good barrier effect , The effect of high safety performance and high antibody activity

Inactive Publication Date: 2018-06-22
广州益琪琳生物科技有限公司
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Desensitization treatment can make about 70% of patients develop tolerance to the corresponding allergens, but the desensitization cycle is as long as more than 3 years, the cost is high, and the treatment must be carried out under the observation of a doctor, so the patient's compliance is not high

Method used

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  • Mite allergen specific yolk immunoglobulin antibody and anti-allergic preparation thereof
  • Mite allergen specific yolk immunoglobulin antibody and anti-allergic preparation thereof
  • Mite allergen specific yolk immunoglobulin antibody and anti-allergic preparation thereof

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Embodiment Construction

[0047] In order to enable those skilled in the art to better understand the technical solutions of the present invention, the present invention will be further described in detail below in conjunction with specific embodiments. The embodiments described below are exemplary, and are only used to explain the present invention, but should not be construed as limiting the present invention. Where specific techniques or conditions are not indicated in the examples, the procedures shall be carried out in accordance with the techniques or conditions described in the literature in the field or in accordance with the product specification.

[0048] In the following, the mite allergen-specific egg yolk immunoglobulin antibody and its anti-allergic preparation of the present invention will be specifically described in conjunction with specific test diagrams.

[0049] The method for preparing the mite allergen-specific IgY antibody of the present invention specifically includes the following s...

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Abstract

The invention relates to a mite allergen specific yolk immunoglobulin antibody and an anti-allergic preparation thereof. The mite allergen specific yolk immunoglobulin antibody is mainly prepared by the following method: extracting a mite allergen, carrying out supplementary immunization on chickens, preparing crude extract, finely extracting and purifying. The mite allergen specific yolk immunoglobulin antibody and the preparation thereof, provided by the invention, have the advantages of high antibody activity and specific defending effect on local sensitization caused by mites, and have a good rejection effect on the local sensitization caused by sensibiligen; the mite allergen specific yolk immunoglobulin antibody has no immunogenicity, no adverse effect on skin mucous membranes of human bodies and high safety performance.

Description

Technical field [0001] The invention belongs to the field of biomedicine, and relates to an egg-yolk immunoglobulin antibody and an anti-allergic preparation thereof, in particular to a mite allergen-specific egg-yolk immunoglobulin antibody and an anti-allergic preparation thereof. Background technique [0002] Allergic rhinitis (allergic rhinitis, AR) is a non-infectious chronic inflammatory disease of the nasal mucosa mediated by IgE after the body is exposed to allergens. A large number of epidemiological surveys at home and abroad show that there are more than 500 million AR patients worldwide. AR has become a major chronic inflammatory disease of the respiratory tract, which has a serious impact on the quality of life of patients and the social economy. Faced with such a high prevalence rate and patients’ requirements for improving the quality of life, various clinical diagnosis and treatment measures have emerged. Local glucocorticoids in the nasal cavity, oral antihistam...

Claims

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Application Information

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IPC IPC(8): C07K16/18A61K39/395A61P11/02A61P37/08A61P11/06A61P17/10
CPCA61K2039/505C07K16/02C07K16/18
Inventor 谢民强
Owner 广州益琪琳生物科技有限公司
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