array sampler

Abstract

The invention discloses an array sample injector. The array sample injector comprises a plurality of sample injection needles, a plurality of liquid storage modules, a plurality of conveying driving devices and an air source, wherein the liquid storage modules and the sample injection needles are connected in a one-to-one correspondence manner; one end of each conveying driving device is connectedwith the air source, and the other ends of the conveying driving devices are connected with the liquid storage modules in the one-to-one correspondence manner and are used for pushing reagents insidethe liquid storage modules to the sample injection needles for outputting and sampling. Sampling different reagents is realized by using different reagent needles, the process of cleaning the reagentneedles is omitted, the time required for sampling is reduced, and the motion structure is simplified, so that the time required for sampling every time can be reduced, the time difference of different section contact reagents in the process of dropwise adding various different first antibody reagents is greatly reduced, the consistency and repeatability of dyeing results are guaranteed, the contact area of the stored reagents and air in the operation process of the instrument is extremely small, and the safety and purity of the reagents are guaranteed.

Description

technical field [0001] The invention relates to the field of biomedical technology experimental equipment, in particular to an array sampler. Background technique [0002] Immunohistochemical staining technology is an important staining method in pathological technology, which has been widely used in pathological work and is one of the important auxiliary means for pathologists to diagnose diseases. For pathology laboratories, a large number of immunohistochemical staining tasks are often performed. [0003] In the current immunohistochemical research and detection test, the conventional staining method generally includes the following steps: the tissue section is baked and dewaxed; then the first antibody reagent corresponding to the tissue section is extracted by the reagent needle, drip After adding it to the tissue section, after incubation, adding the second antibody reagent, developing color, and counterstaining, observe the staining result under a microscope; the dur...

AI Technical Summary

Problems solved by technology

The disadvantages are: (1) The repeated extraction and cleaning of the reagent needle takes a lot of time, especially when adding a wide variety of primary antibody reagents, which will cause the slices to differ from the reagents in different dropping sequences. The difference in contact time is large, which affects the consistency and repeatability of the results; (2) Since the same reagent needle extracts reagents from different reagent containers, cross-contamination of reagents is likely to occur if the cleaning is not thorough; (3) The time spent on the movement of reagents and cleaning reagent needles leads to a greater increase in the time for the instrument to complete complete immunohistochemical staining than for a single slice when there are many slices processed at the same time; (4) Since the reagent container needs to be kept open during the automatic operation state, the reagent has a large area in contact with the air, and is easily polluted by floating objects in the air

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