Structure, preparation and application of novel polyhedral multi-channel high-throughput chromatographic device
What is Al technical title?
Al technical title is built by PatSnap Al team. It summarizes the technical point description of the patent document.
A polyhedral structure and chromatographic device technology, applied in the field of biochemical analysis, can solve the problems of sample waste, inability to detect multiple samples, and inability to detect
Inactive Publication Date: 2018-07-06
INST OF RADIATION MEDICINE ACAD OF MILITARY MEDICAL SCI OF THE PLA +1
View PDF2 Cites 3 Cited by
Summary
Abstract
Description
Claims
Application Information
AI Technical Summary
This helps you quickly interpret patents by identifying the three key elements:
Problems solved by technology
Method used
Benefits of technology
Problems solved by technology
The disadvantages of this type of design are: (1) it is not possible to test multiple indicators on one sample at the same time, (2) it is not possible to test multiple indicators on multiple samples at the same time, which is easy to cause waste of samples
Method used
the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more
Image
Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
Click on the blue label to locate the original text in one second.
Reading with bidirectional positioning of images and text.
Smart Image
Examples
Experimental program
Comparison scheme
Effect test
Embodiment 1
[0037] Embodiment 1, the preparation of polyhedron chromatography device
[0038] Required materials: One Upbox-3D printer was purchased from Beijing Taier Times Technology Co., Ltd. The raw materials ABS, PLA, resin, and polylactic acid were purchased from Beijing Sandi Technology Co., Ltd.
[0039] Operation steps: ① Design the structural model by Auto CAD or SolidWorks software according to the actual needs; ② Input the design model into the Upbox-3D printer for 3D printing.
Embodiment 2
[0040] Example 2, assembly and detection method of 2-channel uplink dihedral chromatography device
[0042] Operation steps: Assembly of single-sample multi-channel device: ① Pass the upper and lower parts of the shell through ( figure 1 )5 parts for connection; ② Insert the 2 sample test strips into the housing ( figure 1 ) in the 1-like structure; ③ take the sample from the shell ( figure 1 ) into 2, gently pipet twice, and the sample passes through the liquid separator ( figure 1 )4 are equally divided one by one; ④ about 5-20min, generally after 10min ( figure 1 ) 3 places to observe the test results.
Embodiment 3
[0043] Example 3, assembly and detection method of 3-channel uplink trihedral chromatography device
[0045] Operation steps: ①Pass the upper and lower parts of the shell through ( figure 2 ) 4 parts to connect; ② Insert the 3 sample test strips into the housing ( figure 2 ) in the 1-like structure; ③ take the sample from the shell ( figure 2 ) into 2, gently pipet twice, and the sample passes through the liquid separator ( figure 2 )5 divided equally one by one; ④ about 5-20min, generally after 10min ( figure 2 ) 3 observations and test results
the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more
PUM
Property
Measurement
Unit
diameter
aaaaa
aaaaa
thickness
aaaaa
aaaaa
Login to view more
Abstract
The invention discloses a novel polyhedral multi-channel high-throughput chromatographic device and application thereof. The device is of a polyhedral structure; the main part of the device is a shell; the device may further have a top cover and a pedestal; and the shell is filled with a drying agent, and the bottom and the top of the device are connected with stepping equipment. The device can realize multi-channel vertical ascending or descending chromatography and perform high-throughput parallel detection and analysis of a plurality of marker molecules on one or more clinical or non-clinical samples at the same time; the device can realize automatic or semi-automatic, qualitative and quantitative analysis with the naked eye in the aid of automatic sample loading, spectroscopic or electromagnetic wave spectrometers and analytical assemblies; target objects to be detected may be biomacromolecules and small-molecular compounds like proteins, nucleic acids and sugars and may be cellular and subcellular components and the like; so the device is applicable to fields like clinical diagnosis, inspection and quarantine, food safety testing, judicial expertise and drug detection. The device is simple to operate, convenient to carry and capable of significantly improving detection efficiency and reducing sample amount.
Description
technical field [0001] The invention relates to an analysis and detection device, which belongs to the field of biochemical analysis, in particular to a polyhedral multi-channel chromatography device, which can simultaneously perform rapid detection of multiple indicators on one sample or multiple samples. Background technique [0002] Immunochromatography is a common rapid detection technology. Usually, the specific antibody is first bound to a specific membrane, and one end of the membrane is immersed in the sample solution, and the sample moves forward along the membrane. When there is an antibody region, the corresponding antigen in the sample will specifically react with the antibody, and then combined with detection methods such as visible light, chemiluminescence, fluorescence, and Raman, the qualitative and quantitative analysis of the antigen content in the sample is carried out. [0003] Immunochromatography technology is widely used in biochemical analysis, pestic...
Claims
the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more
Application Information
Patent Timeline
Application Date:The date an application was filed.
Publication Date:The date a patent or application was officially published.
First Publication Date:The earliest publication date of a patent with the same application number.
Issue Date:Publication date of the patent grant document.
PCT Entry Date:The Entry date of PCT National Phase.
Estimated Expiry Date:The statutory expiry date of a patent right according to the Patent Law, and it is the longest term of protection that the patent right can achieve without the termination of the patent right due to other reasons(Term extension factor has been taken into account ).
Invalid Date:Actual expiry date is based on effective date or publication date of legal transaction data of invalid patent.
Login to view more
Patent Type & Authority Applications(China)
IPC IPC(8): G01N33/558
CPCG01N33/558
Inventor 王升启王娈娈张敏丽王琼
Owner INST OF RADIATION MEDICINE ACAD OF MILITARY MEDICAL SCI OF THE PLA
Login to view more