Traditional Chinese medicine composition for treating neurological diseases and preparation method thereof

A composition and neurological technology, which can be applied to nervous system diseases, drug combinations, metabolic diseases, etc., can solve problems such as many side effects, failure to meet the treatment requirements of medical personnel and patients, and recurrence

Inactive Publication Date: 2018-11-02
SHIJIAZHUANG YILING PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Commonly used analgesics such as ibuprofen (Fenbid), aspirin, aminopyrine, phenylbutazone, etc., and supplementary application of sedatives and vitamins, and adrenal cortex hormones are also reported. However, due to many side effects, recurrence often occurs , requiring a second treatment
Obviously, modern medical treatment can no longer meet the requirements of medical personnel and patients for disease treatment

Method used

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  • Traditional Chinese medicine composition for treating neurological diseases and preparation method thereof
  • Traditional Chinese medicine composition for treating neurological diseases and preparation method thereof
  • Traditional Chinese medicine composition for treating neurological diseases and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0041] Raw materials: Astragalus 10g, Asarum 50g, Salvia miltiorrhiza 5g, Guizhi 50g, Smilax tuckahoe 4g, Angelica 25g, Chuanxiong 3g, Ephedra 20g, Aconite 3g, Radix Paeoniae Rubra 25g, Achyranthes bidentata 5g, Anemarrhena 50g.

[0042] Preparation:

[0043] a. Prepare the above-mentioned raw materials, carry out net selection and processing, and obtain batch materials;

[0044] b. Add 8 times the amount of water to the above ingredients, decoct twice, each time for 1 hour, filter the extract, and then concentrate after removing impurities by centrifugation or ultrafiltration to obtain a concentrate;

[0045] c. Add water to the above-mentioned concentrated solution to make an oral liquid medicinal liquid. After filling, sterilize by flowing steam at 100° C. for 20 minutes to obtain the oral liquid.

Embodiment 2

[0047] Raw materials: Astragalus 80g, Asarum 5g, Salvia 50g, Guizhi 5g, Smilax tuckahoe 40g, Angelica 2g, Chuanxiong 30g, Ephedra 2g, Aconite 40g, Radix Paeoniae Rubra 2g, Achyranthes bidentata 40g, Anemarrhena 5g.

[0048] Preparation:

[0049] a. Prepare the above-mentioned raw materials, carry out net selection and processing, and obtain batch materials;

[0050] b. Add 10 times the amount of water to the above ingredients, decoct twice, each time for 3 hours, filter the extract, and then concentrate after removing impurities by centrifugation or ultrafiltration to obtain a concentrate;

[0051] c. Add water to the above-mentioned concentrated solution to make an oral liquid medicinal liquid. After filling, sterilize by flowing steam at 100° C. for 30 minutes to obtain the oral liquid.

Embodiment 3

[0053] Raw materials: Astragalus 50g, Asarum 25g, Salvia miltiorrhiza 25g, Guizhi 25g, Smilax tuckahoe 25g, Angelica 12.5g, Chuanxiong 20g, Ephedra 15g, Aconite 25g, Radix Paeoniae Rubra 12.5g, Achyranthes bidentata 25g, Anemarrhena 35g.

[0054] Preparation:

[0055] a. Prepare the above-mentioned raw materials, carry out net selection and processing, and obtain batch materials;

[0056] b. Extract volatile oil from Asarum, Guizhi, Angelica, and Rhizoma Chuanxiong, reserve the extract, and wrap the volatile oil with β-cyclodextrin;

[0057] c. Add astragalus, Achyranthes bidentata, Salvia miltiorrhiza, Shang Fuling, red peony root, ephedra, aconite, and anemarrhena to 5 times the amount of water, decoct 3 times, each time for 2 hours, filter respectively, mix with the extract obtained in step b, concentrate, Dried into powder;

[0058] d. Mix the packaged volatile oil with dry medicinal powder, add powdered sugar, and dry to obtain granules.

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Abstract

The invention relates to a traditional Chinese medicine composition for treating neurological diseases and a preparation method thereof, and belongs to the field of traditional Chinese medicine treatment of the neurological diseases, the traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 10-80 parts of radix astragali, 5-50 parts of radix et rhizoma asari, 5-50 parts of radix et rhizoma salviae miltiorrhizae, 5-50 parts of ramulus cinnamomi, 4-40 parts of rhizoma smilacis glabrae, 2-25 parts of radix angelicae sinensis, 3-30 parts of rhizoma chuanxiong, 2-20 parts of herba ephedrae, 3-40 parts of radix aconiti lateralis, 2-25 parts of radix paeoniae rubra, 5-40 parts of radix achyranthis bidentatae, and 5-50 parts of rhizoma anemarrhenae, the traditional Chinese medicine composition provided by the invention can be used for treating diabetic neuropathy, Guillain-Barre syndrome, sciatica, and peripheral neuritis.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine treatment of neurological diseases, and relates to a preparation method of a traditional Chinese medicine composition and preparations for treating neurological diseases. Background technique [0002] Peripheral neuritis refers to the pathogenesis of most peripheral nerves caused by poisoning, infection or allergy. Diseases of autonomic dysfunction. It can occur at any age, and it is more common in young adults. The disease can be acute, subacute, or chronic onset. At the beginning of the disease, the distal extremities are numb or spontaneous pain occurs, and the pain is burning or knife-like. There is a tingling sensation on the sole of the foot. There are also limb weakness, muscle relaxation or atrophy embolism. The main pathogenic factors are ① poisoning: such as lead, arsenic, mercury, phosphorus, barcinoids, isoniazid, streptomycin, phenytoin, vincristine, etc. ②Nutrition an...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/90A61K36/8964A61K47/69A61P25/00A61P25/02A61P3/10
CPCA61K36/17A61K36/21A61K36/232A61K36/236A61K36/268A61K36/481A61K36/537A61K36/54A61K36/65A61K36/71A61K36/714A61K36/896A61K36/8964A61K36/90A61K2236/331A61K2236/39A61K47/6951A61P3/10A61P25/00A61P25/02A61K2300/00
Inventor 贾振华魏聪高怀林
Owner SHIJIAZHUANG YILING PHARMA
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