12 results about "Peripheral neuritis" patented technology

The invention relates to the technical field of plant extracts, and provides a plant extract composition with synergistic hypoglycemic activity and application thereof, and the plant extract composition comprises a mulberry leaf extract, a white kidney bean extract and bitter gourd powder in a mass ratio of 8: (1-24): (1-64). By optimizing the mass ratio of the mulberry leaf extract, the white kidney bean extract and the bitter gourd powder, the blood sugar reducing effect of the plant extract taking the mulberry leaf extract, the white kidney bean extract and the bitter gourd powder as main raw materials is remarkably superior to that of a plant extract in the prior art. Meanwhile, the plant extract composition also has the effects of synergistically reducing the number of neutrophils around nerves, improving peripheral neuroinflammation, synergistically enhancing the fluorescence intensity of the peripheral nerves, improving peripheral nerve injury and inhibiting the enzymatic activity of a bacterium source dipeptidyl peptidase-4.

The present application relates to the technical field of plant extract, and provides a plant extract composition with synergistic hypoglycemic activity and application thereof, wherein the plant extract composition comprises mulberry leaf extract, white kidney bean extract and balsam pear powder with a mass ratio of 8:(1-24):(1-64). The present application optimizes the mass ratio of the mulberry leaf extract, the white kidney bean extract and the balsam pear powder, so that the plant extract with the mulberry leaf extract, the white kidney bean extract and the balsam pear powder as main raw materials has a significantly better effect on reducing blood sugar than the plant extract in the prior art. Meanwhile, the plant extract composition also has the effects of synergistically reducing the number of peripheral nerve neutrophils, improving peripheral nerve inflammation, synergistically enhancing the fluorescence intensity of peripheral nerves, improving peripheral nerve injury, and inhibiting the enzyme activity of bacteria-derived dipeptidyl peptidase-4.

The invention belongs to the technical field of medicines, and particularly discloses a novel 5-6-7-5 ring system beta acid compound, a preparation method thereof and application of the novel 5-6-7-5 ring system beta acid compound in neuroinflammation resistance. The novel 5-6-7-5 ring system beta acid compound provided by the invention is obtained by separation in nature for the first time, and has a good anti-neuroinflammation effect; the compound can be used for developing drugs for treating neuroinflammation related diseases, including but not limited to depression, Alzheimer's disease, Parkinson's disease, Huntington's disease, optic neuromyelitis, peripheral neuritis and the like.

The invention discloses a traditional Chinese medicine composition for treating post-chemotherapy peripheral neuritis, and relates to the technical field of traditional Chinese medicines. The traditional Chinese medicine is prepared from the following raw materials: astragalus membranaceus, cassia twig, radix paeoniae alba, ginger, Chinese dates, fried mustard seeds, angelica sinensis and caulis spatholobi. Comprising the following preparation steps: A, soaking: soaking required medicinal raw materials in cold water for 30-60 minutes, wherein the water is 2-3cm higher than the medicinal materials; wherein the fresh ginger is firstly sliced and then soaked, and the Chinese dates are braised and then soaked together; b, decocting: boiling with big fire, then turning to slow fire, keeping a slight boiling state, decocting for 20-25 minutes, filtering, and collecting liquid medicine; the traditional Chinese medicine composition has the effects of tonifying qi, harmonizing blood, reducing phlegm and dredging collaterals, and is remarkable in curative effect and small in side effect when being used for treating the peripheral neuritis after chemotherapy.

The present invention belongs to the field of biomedicine technology, and specifically relates to the use of divalent metal lactates in the preparation of products for preventing, improving, repairing, and treating nerve damage. Preferably, the divalent metal lactate comprises a combination of one or more of calcium lactate, magnesium lactate, zinc lactate, and ferrous lactate. The present invention provides a new treatment for repairing central and peripheral nerve damage, and has broad application prospects in the treatment and repair of central nervous system damage caused by trauma, or peripheral neuritis or peripheral nerve paresthesia caused by viruses, diabetes, chemotherapy drugs, and other causes.

This invention belongs to the field of biomedical technology and specifically relates to the use of divalent metal lactates in the manufacture of products for the prevention, improvement, repair, and treatment of nerve damage. Preferably, the divalent metal lactate includes one or more of the following: calcium lactate, magnesium lactate, zinc lactate, and ferrous lactate. This invention provides a novel treatment method for repairing damage to the central and peripheral nervous systems and has broad potential applications in the treatment and repair of central nervous system damage caused by trauma or other causes, or peripheral neuritis or peripheral nerve sensory abnormalities caused by viruses, diabetes, chemotherapy drugs, etc.

The invention discloses a Tibetan medicine anti-inflammation inunction preparation and a preparation method thereof, and belongs to the technical field of Tibetan medicines, and the Tibetan medicine anti-inflammation inunction preparation comprises rhubarb, alkali, oxytropis verticillata, herba achyranthis bidentatae, stellera chamaejasme, euphorbia macrocarpa, goethite, folium ilicis scandens, rock brain, volundaisy, gypsum rubrum, rhubarb, thalictrum aquilegifolium, codonopsis alpina, Perot, semen cassiae, abelmoschus esculentus seeds and lagotis diffusa. The medicament has the effects of promoting blood circulation to remove blood stasis, dispelling wind, eliminating dampness, relaxing tendons, dredging collaterals, diminishing inflammation and relieving pain. The traditional Chinese medicine composition can be used for treating joint swelling and pain, limb stiffness, limited activity, hand and foot spasm, neuralgia and other symptoms caused by vasculitis, varicosity, peripheral neuritis, rheumatism, rheumatoid arthritis, gout, fracture and the like, and has effective swelling and pain relieving effects.

The invention belongs to the field of new application of medicines, and particularly relates to application of morusin M in preparation of a medicine for treating peripheral neuritis. In one embodiment, the active ingredients of the medicine further comprise other clinically common medicines for treating peripheral neuritis, and morusin M can significantly enhance the curative effect of other clinically common medicines for treating peripheral neuritis. Pharmacodynamic experiment results show that morusin M can prevent and treat peripheral neuritis caused by chemotherapeutic drugs, relieve temperature sensation and pain sensation sensitive symptoms and improve peripheral nerve toxicity induced by chemotherapeutic drugs. In addition, morusin M can significantly enhance the curative effect of other clinically common drugs for treating peripheral neuritis.

The application belongs to the technical field of medicines, and specifically discloses a novel 5-6-7-5 ring system beta acid compound, a preparation method thereof and application of the compound in resisting neural inflammation. The novel 5-6-7-5 ring system beta acid compound is first separated from nature, has good anti-neural inflammation effect, and can be used for developing medicines for treating neural inflammation related diseases, including but not limited to depression, Alzheimer's disease, Parkinson's syndrome, Huntington's disease, opticospinal neuritis and peripheral neuritis.

This application relates to the pharmaceutical field, and specifically to a multi-TRP ion channel modulator, its preparation method, and its application. The multi-TRP ion channel modulator developed in this application can inhibit TRPV1, activate TRPM8, and activate TRPA1, and can be used to treat functional gastrointestinal disorders, intestinal mucosal damage, intestinal inflammation, immune dysregulation, gut microbiota imbalance, gastrointestinal tumors, pain, or peripheral neuritis.

The invention relates to the field of medicine, in particular to a multi-TRP ion channel regulator and a preparation method and application thereof. The multi-TRP ion channel regulator researched and developed in the invention can inhibit TRPV1, activate TRPM8 and activate TRPA1, and is used for treating functional gastrointestinal diseases, intestinal mucosa injury, intestinal inflammation, immune disorder, dysbacteriosis, digestive tract tumors, pain or peripheral neuritis.

The application belongs to the technical field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine composition for treating peripheral neuritis and a preparation method and application thereof. The traditional Chinese medicine composition is prepared from radix codonopsis, cortex phellodendri, chuanxiong rhizome, acanthopanax, radix puerariae, asarum, earthworm, honeysuckle and licorice. The traditional Chinese medicine composition has the effects of activating blood and removing blood stasis to dredge collaterals, benefiting qi and nourishing blood, and clearing heat and detoxifying, and is mainly used for treating peripheral neuritis patients of qi stagnation and blood stasis. Experimental results show that the traditional Chinese medicine composition can effectively improve the numbness, pain, paresthesia and other symptoms of peripheral neuritis patients, has a remarkable curative effect, and has no toxic and side effects.