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A colorectal cancer tumor marker and its detection method and device

A colorectal cancer, auxiliary detection technology, applied in biochemical cleaning devices, biochemical equipment and methods, enzymology/microbiology devices, etc. Achieve the effect of fast detection cycle, high sensitivity and simple operation

Active Publication Date: 2022-05-06
SHENZHEN HUADA GENE INST
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The traditional screening methods for colorectal cancer are mainly colonoscopy, in addition to biopsy and exfoliative cytology. , few clinical applications

Method used

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  • A colorectal cancer tumor marker and its detection method and device
  • A colorectal cancer tumor marker and its detection method and device
  • A colorectal cancer tumor marker and its detection method and device

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0066] Example 1. Discovery of colorectal cancer tumor markers and establishment of detection methods

[0067] First, the discovery of colorectal cancer tumor markers

[0068] Colorectal cancer gut microbiota markers were searched from the genome of Parvimonas micra by MGWAS method. The finally obtained colorectal cancer intestinal flora marker gene is the gene shown in SEQ ID No. 1 (585 bp) derived from Parvimonas micra.

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Abstract

The invention discloses a colorectal cancer tumor marker, a detection method and a device thereof. The present invention provides a system for detecting whether a test subject is a colorectal cancer patient, including reagents, device A and device B; the reagent can detect target nucleic acid in stool DNA; the device A can use the reagent Detect the content of the target nucleic acid in the test subject's stool DNA; the device B is provided with a functional module; The detection result of the content of the target nucleic acid determines whether the subject is a colorectal cancer patient. The accuracy of the method of the invention is very high, and the method of the invention has the advantages of non-invasiveness, low cost, simple operation, high sensitivity, fast detection cycle and the like. The invention provides effective measures for fast and simple early screening and diagnosis of colon cancer for the general population, and provides a basis for realizing early warning, diagnosis and intervention of colorectal cancer.

Description

technical field [0001] The invention relates to the field of biotechnology, in particular to a colorectal cancer tumor marker and a detection method and device thereof. Background technique [0002] According to statistics, colorectal cancer (CRC) ranks third in incidence and fourth in mortality among various types of cancer, with nearly 55% of the cases occurring in more developed countries. The incidence is low in people younger than 40 years, but the incidence increases with age. Westernization of dietary habits is generally believed to increase the incidence of CRC, but the incidence has remained stable or even decreased in the United States and other high-income countries, presumably related to the increase in sigmoidoscopy and colonoscopic polypectomy. Colorectal cancer is also one of the most preventable tumors. The medical community believes that colorectal cancer is the most curable cancer if detected early. The traditional screening methods for colorectal cancer ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): C12Q1/6886C12N15/11C12M1/34C12M1/00
CPCC12Q1/6886C07K14/195
Inventor 李南南揭著业易吉吴逵朱师达贾慧珏仝欣罗慧娟陈小芳
Owner SHENZHEN HUADA GENE INST
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