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Colorectal cancer tumor marker and detection method and device thereof

A colorectal cancer and primer pair technology, applied in the biological field, can solve the problems of cumbersome collection of materials, difficult to obtain satisfactory specimens, few clinical applications, etc., and achieve the effects of simple operation, fast detection cycle and high sensitivity

Pending Publication Date: 2022-05-06
SHENZHEN HUADA GENE INST
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The traditional screening methods for colorectal cancer are mainly colonoscopy, in addition to biopsy and exfoliative cytology. , few clinical applications

Method used

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  • Colorectal cancer tumor marker and detection method and device thereof
  • Colorectal cancer tumor marker and detection method and device thereof
  • Colorectal cancer tumor marker and detection method and device thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0067] Example 1. Discovery of colorectal cancer tumor markers and establishment of detection methods

[0068] 1. Discovery of tumor markers in colorectal cancer

[0069] The MGWAS method was used to find the markers of colorectal cancer intestinal flora from the genome of Micromonas micromonas (Parvimonas micra). The finally obtained colorectal cancer intestinal flora marker gene is the gene (585bp) shown in SEQ ID No.1 derived from Parvimonas micra.

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Abstract

The invention discloses a colorectal cancer tumor marker and a detection method and device thereof. The invention provides a system for detecting whether a to-be-detected person is a colorectal cancer patient or not. The system comprises a reagent, a device A and a device B, the reagent can be used for detecting target nucleic acid in excrement DNA (Deoxyribonucleic Acid); the device A can detect the content of the target nucleic acid in the excrement DNA of a to-be-detected person by using the reagent; a function module is arranged in the device B; the functional module can determine whether the person to be detected is a colorectal cancer patient or not according to a detection result of the content of the target nucleic acid in the excrement DNA of the person to be detected, wherein the detection result is detected by the device A. The method disclosed by the invention is very high in accuracy, and has the advantages of noninvasive property, low cost, simplicity in operation, high sensitivity, short detection period and the like. The invention provides rapid, simple and effective measures for early screening and diagnosis of colorectal cancer for the majority of people, and provides a basis for early warning, diagnosis and intervention of colorectal cancer.

Description

[0001] This application is a divisional application with the application number 201810676153.6, the application date is June 27, 2018, and the invention name is "a colorectal cancer tumor marker and its detection method and device" technical field [0002] The invention relates to the field of biotechnology, in particular to a colorectal cancer tumor marker and a detection method and device thereof. Background technique [0003] According to statistics, colorectal cancer (CRC) ranks third in incidence and fourth in mortality among various cancers, and nearly 55% of the cases occur in developed countries. The incidence rate is low in people younger than 40 years old, but the incidence rate gradually increases with age. It is generally believed that Westernization of dietary habits will increase the incidence of CRC, but the incidence in the United States and other high-income countries has remained stable or even decreased, which is speculated to be related to the increase in...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C12Q1/6886C12N15/31C12N15/11
CPCC12Q1/6886C07K14/195
Inventor 李南南揭著业易吉吴逵朱师达贾慧珏仝欣罗慧娟陈小芳
Owner SHENZHEN HUADA GENE INST
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