Preparation apparatus of individualized bionic bone tissue support

A tissue scaffold and preparation device technology, applied in tissue regeneration, medical science, prosthesis, etc., can solve the problems of difficult entry of cells and blood vessels, affecting the osteogenesis in the scaffold, etc., and achieve uniform and rapid temperature cooling and complete osteogenesis. Effect

Pending Publication Date: 2018-12-18
THE THIRD XIANGYA HOSPITAL OF CENT SOUTH UNIV
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although the scaffold material prepared by this method has an ordered lamellar porous structure inside, the dense peripheral structure of the scaffold makes it difficult for cells and blood vessels to enter the scaffold, thus affecting the osteogenesis in the scaffold.

Method used

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  • Preparation apparatus of individualized bionic bone tissue support
  • Preparation apparatus of individualized bionic bone tissue support

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Experimental program
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Embodiment 1

[0037] Such as figure 1 As shown, a preparation device for a personalized bionic bone tissue support includes a personalized mold and a cold circulation system communicated through an adapter 5;

[0038] The personalized mold includes a mold lock 1, a mold shell 4 connected by the mold lock 1, a central cold source copper tube 3 arranged on the inner axis of the mold shell 4, and a slurry injection port arranged on the mold shell 4 2. The mold shell 4 is divided into two pieces by the central axis, and the mold is clamped and fixed by the mold lock 1, and the bracket material can also be easily demoulded by releasing the mold lock 1, and its shape can be individually designed according to different bone defects , the raw material of the mold shell is glass fiber reinforced plastic, and the material of glass fiber reinforced plastic is also conducive to directly observing the injection and freezing conditions of the slurry in the mold;

[0039] The cold circulation system incl...

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Abstract

The invention provides a preparation apparatus of an individualized bionic bone tissue support. The preparation apparatus comprises an individualization mold and a cold circulating system which are communicated by virtue of an adaptoor; the individualization mold comprises a mold lock catch, a mold shell connected with the mold lock catch, a center cold source copper pipe arranged on the central axis in the mold shell and a slurry injection opening arranged on the mold shell; the cold circulating system comprises a freezing circulating box, a micro diaphragm pump, a cold source conduction copper column and a refrigeration compressor; the cold source conduction copper column is connected with the freezing circulating box and the refrigeration compressor; freezing liquid is poured into the freezing circulating box; and the freezing liquid enters the center cold source copper pipe to be circularly condensed along a freezing circulating box external pipeline by virtue of the effect of themicro diaphragm pump. According to the preparation apparatus of the invention, the traditional single-end cold source way is changed, and the individualization bionic bone tissue mold is adopted, so that an effect for preparing the individualized bionic bone support can be realized.

Description

technical field [0001] The present invention relates to the technical field of biomedical materials and equipment, in particular, to a preparation device for a personalized bionic bone tissue support, in particular to a preparation device for a personalized layer-like gradient porous bionic bone tissue support, and to prepare the bionic bone tissue support The method of the device and the method of preparing the personalized layered gradient porous bionic bone tissue scaffold. Background technique [0002] Scaffold materials for bone repair should have good plasticity, biocompatibility, osteoconductivity, bioactivity, and degradability, as well as high porosity, interconnected porous structure, and sufficient mechanical strength. However, the existing bone repair materials, such as metal implant materials such as titanium and titanium alloys, stainless steel, and cobalt-chromium alloys, can be individually designed according to the shape of bone defects and have good mechani...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L27/56A61L27/36B33Y30/00B33Y50/02
CPCA61L27/56A61L27/3608A61L27/365A61L2430/02B33Y30/00B33Y50/02
Inventor 陈良建
Owner THE THIRD XIANGYA HOSPITAL OF CENT SOUTH UNIV
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