Protein feature extraction method, functional model generation method, function prediction method and corresponding devices

A technology for protein function and feature extraction, applied in the field of bioinformatics, can solve problems such as time-consuming and labor-intensive

Active Publication Date: 2019-01-15
NEUSOFT CORP
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Problems solved by technology

[0004] In view of this, the embodiment of the present application provides a method and device for protein feature extraction on the one hand, a method and device for generating protein function models on the other hand, and a method for protein fun...

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  • Protein feature extraction method, functional model generation method, function prediction method and corresponding devices
  • Protein feature extraction method, functional model generation method, function prediction method and corresponding devices
  • Protein feature extraction method, functional model generation method, function prediction method and corresponding devices

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Embodiment Construction

[0088] In order to enable those skilled in the art to better understand the solution of the present application, the technical solution in the embodiment of the application will be clearly and completely described below in conjunction with the accompanying drawings in the embodiment of the application. Obviously, the described embodiment is only It is a part of the embodiments of this application, not all of them. Based on the embodiments in this application, all other embodiments obtained by persons of ordinary skill in the art without making creative efforts belong to the scope of protection of this application.

[0089] It should be understood that in this application, "at least one (item)" means one or more, and "multiple" means two or more. "And / or" is used to describe the association relationship of associated objects, indicating that there can be three types of relationships, for example, "A and / or B" can mean: only A exists, only B exists, and A and B exist at the same...

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Abstract

The embodiments of the present invention disclose a protein feature extraction method, a functional model generation method, a function prediction method and corresponding devices. The protein featureextraction method includes the following steps that: the amino acid sequences of a target protein and residue action sites on the amino acid sequence of the target protein are acquired, so that the target amino acid sequence and target residue acting sites can be obtained; an amino acid abbreviation code or a plurality of consecutive amino acid abbreviation codes are intercepted from the target amino acid sequence, so that a target character string containing the target residue action sites is obtained; and the textual features of the target character string in the amino acid sequence are extracted. According to the methods and devices, the features of the residue action sites in the amino acid sequence are adopted as the expressions of protein functions, high-quality feature input can beprovided for subsequent protein function prediction by machine learning algorithms, the abandonment of time-consuming labor-consuming manual prediction methods can be benefitted, and the efficiency and accuracy of protein function prediction can be improved.

Description

technical field [0001] The present application relates to the field of biological information technology, and in particular to a method and device for protein feature extraction, function model generation, and function prediction. Background technique [0002] With the continuous development of life science research, people gradually realize that genome information can no longer fully explain and predict various life processes and phenomena. Proteins, as executors of cellular activity and functions, have received increasing attention. Knowing the function of proteins in advance will help to understand the mechanism of biochemical reactions in cells, and then guide drug design. [0003] The function of protein, specifically expressed as the interaction between protein and protein, protein and carbohydrate, protein and lipid, protein and deoxyribonucleic acid (DNA) or ribonucleic acid (Ribonucleic acid, RNA), protein and metal ion ability. In the past ten years, a variety o...

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Application Information

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IPC IPC(8): G16B25/00G16B30/00
Inventor 汤一凡崔朝辉赵立军张霞
Owner NEUSOFT CORP
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