Traditional Chinese medicine composition for resisting breast cancer, traditional Chinese medicine preparation and preparation method of preparation

A technology of anti-breast cancer and traditional Chinese medicine preparations, which is applied in drug combinations, anti-tumor drugs, and pharmaceutical formulas, can solve the problems of low killing efficiency of breast cancer cells and high toxicity and side effects, and achieve rigorous drug use, low toxicity and side effects, and anti-tumor Enhanced effect

Inactive Publication Date: 2019-01-22
SOUTHWEST JIAOTONG UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Aiming at the above-mentioned problems existing in the prior art, the present invention provides an anti-breast cancer Chinese medicine composition, a Chinese medicine preparation and a preparation method thereof, and the Chinese medicine preparation prepared by using the Chinese medicine composition and method of the present invention can effectively solve the existing problems. In the anti-cancer process of chemicals, there are many problems such as large toxic side effects and low killing efficiency of breast cancer cells

Method used

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  • Traditional Chinese medicine composition for resisting breast cancer, traditional Chinese medicine preparation and preparation method of preparation
  • Traditional Chinese medicine composition for resisting breast cancer, traditional Chinese medicine preparation and preparation method of preparation
  • Traditional Chinese medicine composition for resisting breast cancer, traditional Chinese medicine preparation and preparation method of preparation

Examples

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Embodiment 1

[0036] A traditional Chinese medicine composition for fighting breast cancer, comprising the following components in parts by weight: 10 parts of arborvitae, 10 parts of Fangfeng, 10 parts of Angelica dahurica, 10 parts of Sophora flavescens, and 20 parts of Hedyotis diffusa.

[0037] The traditional Chinese medicine preparation prepared from the above-mentioned anti-breast cancer traditional Chinese medicine composition is a tincture.

[0038] The preparation method of the above-mentioned anti-breast cancer traditional Chinese medicine preparation includes the following steps: take the medicinal materials of the formula, add 75% alcohol 8 times the weight of the total medicinal materials to it, soak in a sealed bottle, stir once every 5 days, and filter after 40 days , to collect the ethanol extract, prepared.

Embodiment 2

[0040] A traditional Chinese medicine composition for fighting breast cancer, comprising the following components in parts by weight: 30 parts of arborvitae, 20 parts of Fangfeng, 20 parts of Angelica dahurica, 20 parts of Sophora flavescens, and 3 parts of Hedyotis diffusa.

[0041] The traditional Chinese medicine preparation prepared from the above-mentioned anti-breast cancer traditional Chinese medicine composition is an oral liquid.

[0042] The preparation method of the above-mentioned anti-breast cancer traditional Chinese medicine preparation comprises the following steps: (1) take the medicinal materials of the formula, add 75% alcohol 8 times the weight of the total medicinal materials to it, soak in a sealed bottle, stir once every 3 days, After 40 days, filter and collect the ethanol extract for subsequent use;

[0043] (2) Adding 0.3 times the weight of sucrose of the ethanol extract to the ethanol extract prepared in step (1), and mixing evenly to prepare.

Embodiment 3

[0045] A traditional Chinese medicine composition for fighting breast cancer, comprising the following components in parts by weight: 10 parts of arborvitae, 10 parts of Fangfeng, 60 parts of Angelica dahurica, 10 parts of Sophora flavescens, and 3 parts of Hedyotis diffusa.

[0046] The traditional Chinese medicine preparation prepared from the above-mentioned anti-breast cancer traditional Chinese medicine composition is a granule.

[0047] The preparation method of the above-mentioned anti-breast cancer traditional Chinese medicine preparation comprises the following steps: (1) take the medicinal materials of the formula amount, add 75% alcohol which is 8 times the weight of the total medicinal materials to it, soak in a sealed bottle, stir once every 6 days, Filter after 50 days, collect the ethanol extract, and set aside;

[0048] (2) Weigh 0.1 times the weight of sucrose from the ethanol extract and 0.2 times the weight of dextrin from the ethanol extract, put them into ...

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Abstract

The invention provides a traditional Chinese medicine composition for resisting breast cancer, a traditional Chinese medicine preparation and a preparation method of the preparation. The traditional Chinese medicine composition comprises 10 to 60 parts of cacumen platycladi, 10 to 60 parts of radix saposhnikoviae, 10 to 60 parts of radix angelicae dahuricae, 10 to 60 parts of radix sophorae flavescentis, and 3 to 65 parts of spreading hedyotis herb. The traditional Chinese medicine preparation includes the forms of a tincture, an oral liquid, a granule, a capsule or a tablet. The preparation method of the traditional Chinese medicine preparation comprises the steps of firstly mixing all the medicine materials, adding 75% alcohol with a weight being 4-12 times of the weight of the total medicine materials, conducting sealing in a bottle, placing the bottle in a cool place, conducting stirring once every 3 to 9 days, conducting filtering after 30 to 70 days, collecting an ethanol extract, and then using the ethanol extract and corresponding adjuvant materials to prepare a corresponding preparation form. The traditional Chinese medicine composition of the invention can effectively kill breast cancer cells, has a killing effect on lung cancer cells, liver cancer cells, human melanoma cells, etc., and can effectively inhibit migration of breast cancer cells.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine pharmacy, and in particular relates to an anti-breast cancer traditional Chinese medicine composition, a traditional Chinese medicine preparation and a preparation method thereof. Background technique [0002] Breast cancer is one of the most common malignant tumors in women. According to statistics, the incidence rate accounts for 7-10% of various malignant tumors in the whole body, and it is second only to cervical cancer in women. Risk factors for breast cancer include: exposure to high doses of radiation to the chest, long-term use of exogenous estrogen, postmenopausal obesity, long-term excessive drinking, and carrying mutated genes associated with breast cancer. Known breast cancer susceptibility genes include BRCA-1, BRCA-2, p53, PTEN, etc. Breast cancers related to these gene mutations are called hereditary breast cancers, accounting for 5% to 10% of all breast cancers...

Claims

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Application Information

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IPC IPC(8): A61K36/748A61P35/00
CPCA61K36/14A61K36/232A61K36/238A61K36/489A61K36/748A61K2236/333A61P35/00A61K2300/00
Inventor 茆灿泉王蔚李迪强邹金晶敖智广郝静
Owner SOUTHWEST JIAOTONG UNIV
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