Multi-index microfluidic chip and using method thereof

A microfluidic chip and multi-indicator technology, applied in chemical instruments and methods, laboratory containers, material inspection products, etc., can solve problems affecting the quality of coated antibodies/antigens and inaccurate test results

Active Publication Date: 2019-05-10
NANJING LANSION BIOTECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0009] In the production process, the layered microfluidic chips currently on the market are generally coated with antibodies/antigens first, and then the chips of each layer are bonded and assembled as soon as pos

Method used

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  • Multi-index microfluidic chip and using method thereof
  • Multi-index microfluidic chip and using method thereof
  • Multi-index microfluidic chip and using method thereof

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Embodiment Construction

[0101] The following will clearly and completely describe the technical solutions in the embodiments of the present invention with reference to the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only some, not all, embodiments of the present invention. The following description of at least one exemplary embodiment is merely illustrative in nature and in no way taken as limiting the invention, its application or uses. Based on the embodiments of the present invention, all other embodiments obtained by persons of ordinary skill in the art without creative efforts fall within the protection scope of the present invention. The relative arrangements, expressions and numerical values ​​of components and steps set forth in these embodiments do not limit the scope of the present invention unless specifically stated otherwise. At the same time, it should be understood that, for the convenience of description, the sizes of the...

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Abstract

The invention discloses a multi-index microfluidic chip and a using method thereof. The multi-index microfluidic chip comprises a chip body, wherein the chip body is provided with a sample injection chamber, a plurality of quantitative reaction chambers and a waste liquid chamber; the sample injection chamber comprises a sample filter pool, a filter membrane and a sample injection part disposed atthe port of the sample filter pool; the filter sample pool is arranged in the shape of a palm-leaf fan, and the liquid outlet of the sample filter pool is arranged on the narrow side wall; the lowerend of the sample injection part has a sample injection hole penetrating the sample filter pool; the upper end of the sample injection part comprises two parts of a flow guiding surface and a ventingboss respectively; the flow guiding surface is a curved surface which is gradually tapered from the outside to the inside; the venting boss has a venting hole penetrating the sample filter pool; the venting boss is located close to the wide side wall of the sample filter pool, the flow guiding surface is disposed adjacent to the narrow side wall of the sample filter pool; and the bottom of the sample filter pool is provided with a plurality of rib protrusions along the flow direction of the fluid. Therefore, the invention can effectively improve the filtration efficiency of the microfluidic chip.

Description

technical field [0001] The invention relates to a multi-index microfluidic chip; [0002] The present invention also relates to a method for using the above-mentioned microfluidic chip. Background technique [0003] There are two types of microfluidics: passive and active. Passive microfluidics still requires capillary force to achieve liquid-forward lateral flow. However, due to the different viscosities of different samples, especially whole blood samples, the liquid flow rate cannot be uniform. Active microfluidics can effectively avoid the above problems, and can give forward thrust to make the liquid flow forward evenly, avoiding the difference in test values ​​caused by different flow rates. The power of active microfluidics includes centrifugal force drive, electrowetting drive, and pressure drive (electrolytic pump, compressed gas pump, chemical decomposition pump, direct air pressure differential drive). However, if the purpose of controlling the liquid flow at ...

Claims

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Application Information

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IPC IPC(8): G01N33/533G01N33/68B01L3/00
Inventor 许行尚杰弗瑞·陈于沛
Owner NANJING LANSION BIOTECH CO LTD
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