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Method capable of quickly increasing leech antithrombase content

A technology of antithrombin and leeches, applied in the field of collection of medicinal animal raw materials

Inactive Publication Date: 2019-06-28
NANJING AGRICULTURAL UNIVERSITY
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0003] At present, it is found that the processing method, harvesting period, and different parts have a significant impact on the antithrombin activity of leeches, and different feeding densities have no significant impact on the antithrombin activity of leeches.
At present, there are few reports on the effect of smoking behavior on the anticoagulant activity of leeches, and the literature on the anticoagulant activity of leeches rarely mentions the correlation between the time of sample collection and smoking

Method used

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  • Method capable of quickly increasing leech antithrombase content
  • Method capable of quickly increasing leech antithrombase content

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specific Embodiment 1

[0034] The present invention selects about 15g of healthy leeches (Whitmania pigra Whitman), places 15g of leeches in a plastic container, temporarily raises them in clear water for 1 week to discharge feces, starts to feed snails after changing the water, and observes the feeding situation. At the beginning, 24 hours is a day, and the leeches on the 5th day after ingestion are selected for harvesting and processing.

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Abstract

The invention provides a method capable of quickly increasing leech antithrombase active content. The method is simple and convenient in operation and can obtain high-quality leech medicinal materials. By adopting the method, overall antithrombase total content of leech is maximum in the 5th day after sucking, which is increased by 49.5%, 73.5%, 69.1% and 126.0% when compared with that in the 1stday, the 3rd day, the 7th day and the 11th day after sucking. By applying the method, antithrombase activity of the leech is improved remarkably without increasing production cost, and leech medicinalmaterial quality is improved.

Description

1. Technical field [0001] The invention relates to a method for increasing the content of antithrombin in leeches, belonging to the field of medicinal animal raw material collection. 2. Background technology [0002] Leech Whitmania pigra Whitman belongs to the family Annelida (Haemopidae). The dry whole is leech, a traditional Chinese medicinal material. The main active ingredient of leech-like Chinese medicinal materials is antithrombin substance, which has the functions of breaking blood and stimulating menstruation, removing blood stasis and eliminating symptoms. It is the main raw material of many Chinese patent medicines for treating cardiovascular diseases. mainstream varieties in the market. [0003] At present, it is found that the processing method, harvesting period, and different parts have a significant impact on the antithrombin activity of leeches, but different feeding densities have no significant impact on the antithrombin activity of leeches. At present,...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A01K61/40A23K50/80A23K10/22
CPCY02A40/818
Inventor 史红专郭巧生吴曼郡
Owner NANJING AGRICULTURAL UNIVERSITY
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