Application of formononetin to preparation of drugs for treating pulmonary hypertension and drugs for treating pulmonary hypertension

A technology of pulmonary arterial hypertension and formononetin, applied in the field of medicine, can solve the problems of high fatality rate, missed the best opportunity for treatment and rehabilitation, and increased treatment and nursing costs, so as to inhibit growth and proliferation, improve immunity, improve Effects of right ventricular hypertrophy

Inactive Publication Date: 2019-08-20
LISHUI CENT HOSPITAL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0002] Pulmonary hypertension is a common disease with a high fatality rate. If the disease is ignored, it will continue to deteriorate and lead ...

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  • Application of formononetin to preparation of drugs for treating pulmonary hypertension and drugs for treating pulmonary hypertension
  • Application of formononetin to preparation of drugs for treating pulmonary hypertension and drugs for treating pulmonary hypertension
  • Application of formononetin to preparation of drugs for treating pulmonary hypertension and drugs for treating pulmonary hypertension

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Embodiment Construction

[0055] The following will clearly and completely describe the technical solutions in the embodiments of the present invention with reference to the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only some, not all, embodiments of the present invention. Based on the embodiments of the present invention, all other embodiments obtained by persons of ordinary skill in the art without making creative efforts belong to the protection scope of the present invention.

[0056] In order to better describe and illustrate the embodiments of the application, reference may be made to one or more drawings, but additional details or examples used to describe the drawings should not be regarded as an invention of the application, the presently described implementation limitations on the scope of any of the examples or preferred modes.

[0057] It should be noted that when a component is said to be "connected" to another component, it...

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Abstract

The invention discloses application of formononetin to preparation of drugs for treating pulmonary hypertension and the drugs for treating pulmonary hypertension. The pulmonary hypertension drugs areoral drugs or injection drugs. The pulmonary hypertension drugs in the form of injection drugs are obtained by dissolving the formononetin in pharmaceutical solvents. The pharmaceutical solvents comprise dimethyl sulfoxide and/or olive oil. According to the present invention, the proliferation of pulmonary artery smooth muscle cells can be inhibited and the apoptosis of the pulmonary artery smoothmuscle cells can be promoted by the formononetin, pulmonary vascular remodeling can be significantly improved, pulmonary vascular resistance and pulmonary artery pressure can be reduced, the formononetin plays a role in reducing blood pressure stably, pulmonary function and right heart function can be restored, human impaired function can be normalized and complications can be treated as a whole.

Description

technical field [0001] The invention relates to the field of medicine, in particular to the application of formononetin in the preparation of medicine for treating pulmonary hypertension and the medicine for treating pulmonary hypertension. Background technique [0002] Pulmonary hypertension is a common disease with a high mortality rate. If left untreated, it will continue to deteriorate and lead to right heart failure, which will not only increase the cost of treatment and care, but also miss the best opportunity for treatment and rehabilitation. [0003] Pulmonary hypertension is a chronic and progressive cardiovascular disease with complex etiology leading to elevated pulmonary artery pressure. Reasonable treatment of patients with pulmonary arterial hypertension is very important to improve the prognosis. Contents of the invention [0004] Based on this, it is necessary to improve a drug that can effectively reduce pulmonary hypertension and improve the survival stat...

Claims

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Application Information

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IPC IPC(8): A61K31/352A61P9/12A61P11/00
CPCA61K31/352A61P9/12A61P11/00
Inventor 曾春来蔡昌宏向贻佳吴勇辉
Owner LISHUI CENT HOSPITAL
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