Artemisia rupestris and radix isatidis plague removal granule and preparing method and application thereof

Abstract

The invention belongs to the technical field of traditional Chinese medicines for animals, and particularly relates to an artemisia rupestris and radix isatidis plague removal granule and a preparing method and application thereof. In the preparing process of the artemisia rupestris and radix isatidis plague removal granule, through the combination of an ethyl alcohol reflux extraction method and a water decoction extraction method, artemisia rupestris and other raw materials are extracted, alcohol-soluble and water-soluble effective active components are sufficiently obtained, and the main effective components can be well stored in the finally-obtained artemisia rupestris and radix isatidis plague removal granule. Compared with the defect that traditional Chinese herbal medicine powder and preparations are high in coarse fiber content and effective components can hardly be dissolved out in the prior art, since the artemisia rupestris and radix isatidis plague removal granule is high in effective component content, easy to absorb and high in bioavailability, the artemisia rupestris and radix isatidis plague removal granule can have a better clinical effect on the aspects of resisting the external pathogenic heat of muscovy duck parvovirus to invade lung channels, liver channels and kidney channels and protecting the liver and kidneys. In addition, the artemisia rupestris and radix isatidis plague removal granule can be rapidly and completely dissolved in livestock drinking water without blocking a breeding water drinking system and can be conveniently used in poultry farms on a large scale.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine for veterinary use, and in particular relates to a haolanyqing granule, its preparation method and application. Background technique [0002] Muscovy Duck Parvovirosis (MP), commonly known as "three-week disease", is an acute, septic, viral infectious disease caused by Muscovy Duck Parvovirus (MPV). It mainly affects young muscovy ducks within 3 weeks of age. It is highly contagious and has high morbidity and mortality. It is characterized by asthma, diarrhea, organ hemorrhage, ataxia and neurological symptoms, which seriously affects the growth of muscovy ducks. The disease can occur throughout the year and is one of the main diseases that endanger the duck industry. [0003] At present, the prevention and treatment of MP in China generally includes vaccines, antiviral drugs and traditional Chinese medicines. Although the use of vaccines has played a certain role in prevent...

AI Technical Summary

Problems solved by technology

Although the use of vaccines has played a certain role in preventing and controlling the prevalence of MP, due to the high infectivity of MP and the complexity of MPV serotypes, there is little cross-protection or even no cross-protection between different serotype strains. sex, complicating and increasing the cost of immunization prophylaxis

Therefore, MP is still occurring and spreading in immunized and non-immunized duck populations at present, causing severe economic losses to the poultry industry

In terms of chemical medicine, the treatment of this disease is mainly based on palliative treatment, because chemical antiviral drugs such as ribavirin are prohibited in food animals, and quinolones, cephalosporins and other antibacterial and anti-inflammatory drugs are often used clinically to prevent secondary infection and reduce the risk of infection. Mortality is the purpose, but often results in excessive antibiotic residues, threatening human health and life safety

In terms of traditional Chinese medicine, Jingfangbaidu powder, Mahuang Guizhi powder, etc. have been tried, mainly to improve immunity, clear away heat and detoxify, and the mixing materials are inconvenient, costly, and the cure rate is low.

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