Application of polyrhachis vicina extract in preparation of medicines for preventing and treating breast cancer and related diseases

A technology for simulating black spiny ants and extracts, which is applied in the field of natural extracts, can solve problems such as literature reports that have no anti-breast cancer effect, and achieves the advantages of large-scale production, simple and easy preparation methods, and easy-to-obtain raw material sources. Effect

Inactive Publication Date: 2020-05-01
GUANGXI INST OF CHINESE MEDICINE & PHARMA SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] Existing literature shows that Pseudomonas spp. has rich pharmacological activities, but there is no literature report on the anti-breast cancer effect

Method used

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  • Application of polyrhachis vicina extract in preparation of medicines for preventing and treating breast cancer and related diseases
  • Application of polyrhachis vicina extract in preparation of medicines for preventing and treating breast cancer and related diseases

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] The preparation of embodiment 1 pseudoblack spiny ants extract

[0023] Take 1000g of Pseudomonas spp., add "petroleum ether (60-90°C)" produced by Tianjin Damao Chemical Reagent Factory, heat and reflux at 30°C to extract 3 times, 3L each time, combine the extracts, and recover petroleum ether under reduced pressure (60-90° C.) and concentrated to obtain the extract.

Embodiment 2

[0024] The preparation of embodiment 2 Pseudomonas spiny ants extract

[0025] Take 1000g of Pseudomonas spiny ants, add "petroleum ether (60-90°C)" produced by Tianjin Damao Chemical Reagent Factory, heat and reflux at 40°C to extract twice, 3L each time, combine the extracts, and recover petroleum ether under reduced pressure (60-90° C.) and concentrated to obtain the extract.

Embodiment 3

[0026] Embodiment 3 Preparation of Pseudomonas spinosa ants extract

[0027] Take 1000g of Pseudomonas spp., add "petroleum ether (60-90°C)" produced by Tianjin Damao Chemical Reagent Factory, heat and reflux at 60°C to extract 4 times, 3L each time, combine the extracts, and recover petroleum ether under reduced pressure (60-90° C.) and concentrated to obtain the extract.

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Abstract

The invention discloses an application of a polyrhachis vicina extract in preparation of medicines for preventing and treating breast cancer and related diseases. An extraction method of the polyrhachis vicina extract comprises the following steps: taking polyrhachis vicina powder, adding an organic solvent, performing heating reflux extraction, recovering the organic solvent at reduced pressure,and performing concentration to obtain the extract. The invention finds for the first time that the polyrhachis vicina extract has obvious anti-breast cancer activity, and the patent medicine potential to prepare the anti-breast cancer medicines or the medicines having anti-breast cancer functions, provides a novel material foundation for development of the innovative anti-breast cancer medicines,and has potentially huge social and economic benefits.

Description

technical field [0001] The invention belongs to the technical field of natural extracts, and in particular relates to the use of an extract from the ants of Pterocarpus in the preparation of medicines for preventing and treating breast cancer and related diseases. Background technique [0002] Breast cancer is one of the most common malignant tumors in women, and its incidence rate increases year by year, seriously endangering the health of women. At present, breast cancer treatment mainly includes surgery, radiotherapy and chemotherapy, endocrine therapy, targeted drug therapy and adjuvant therapy of traditional Chinese medicine. Nearly 50 years of clinical practice have shown that: traditional Chinese medicine treatment of tumors has obvious advantages in improving the internal environment of the body, survival with tumors, and prevention and treatment of tumor metastasis and recurrence. At the same time, traditional Chinese medicine can reduce adverse reactions to patien...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K35/64A61P35/00
CPCA61K35/64A61P35/00
Inventor 李冬梅韦洁何俊慧韦桂宁何飞
Owner GUANGXI INST OF CHINESE MEDICINE & PHARMA SCI
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