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Fluorescence detection device based on micro-fluidic chip and micro-fluidic chip detection system

A microfluidic chip, fluorescence detection technology, applied in measurement devices, fluorescence/phosphorescence, material analysis by optical means, etc., can solve the problems of high technical level requirements, complex, numerous steps, etc., to achieve real-time quantitative The effect of detection

Active Publication Date: 2020-05-22
XIAMEN UNIV +1
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

However, the nucleic acid detection process is very complicated, with many steps, and has high requirements for the detection environment, laboratory conditions, and technical level of personnel. Therefore, the development trend of nucleic acid detection is fully automatic integration, high integration, real-time detection, and detection anywhere.

Method used

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  • Fluorescence detection device based on micro-fluidic chip and micro-fluidic chip detection system
  • Fluorescence detection device based on micro-fluidic chip and micro-fluidic chip detection system

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Embodiment Construction

[0030] The technical solutions in the embodiments of the present invention will be clearly and completely described below in conjunction with the drawings in the embodiments of the present invention. Apparently, the described embodiments are only some of the embodiments of the present invention, not all of them. Based on the embodiments of the present invention, all other embodiments obtained by persons of ordinary skill in the art without creative efforts fall within the protection scope of the present invention.

[0031] In describing the present invention, it is to be understood that the terms "central", "longitudinal", "transverse", "front", "rear", "left", "right", "vertical", "horizontal", The orientations or positional relationships indicated by "top", "bottom", "inner", "outer", etc. are based on the orientations or positional relationships shown in the drawings, and are only for the convenience of describing the present invention and simplifying the description, rathe...

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Abstract

The present invention relates to a fluorescence detection device based on a micro-fluidic chip and a micro fluidic chip detection system, the fluorescence detection device comprises: a base; at leasttwo light path assemblies fixedly arranged on the base, and each of the at least two light path assemblies comprising an excitation light path module and a collection light path module; a first bracket movably arranged on the base; a first optical fiber whose first end penetrates through and is fixed on the first bracket and second end is used for being close to the chip and transmitting light tothe chip; and a second optical fiber whose first end of the penetrates through and is fixed to the first support and second end is used for being close to the chip and recycling light in the chip. Thefirst end of the first optical fiber and the first end of the second optical fiber are configured to move along with the first bracket and are selectively and correspondingly connected with an excitation light path module and a collection light path module in one of the at least two light path assemblies respectively. According to the invention, switching of a plurality of required light can be autonomously controlled in the biochemical reaction process.

Description

technical field [0001] The invention relates to the field of in vitro diagnostic equipment, in particular to a microfluidic chip-based fluorescence detection device and a microfluidic chip detection system. Background technique [0002] Nucleic acid detection technology is a technology that directly detects the genetic material of living organisms, such as DNA and RNA. Its specificity and sensitivity are extremely high, the window period is short, and it has multiple detection capabilities. However, the nucleic acid detection process is very complicated, with many steps, and has high requirements for the detection environment, laboratory conditions, and technical level of personnel. Therefore, the development trend of nucleic acid detection is fully automatic integration, high integration, real-time detection, and detection anywhere. . In the field of in vitro diagnostics, such small, portable, fast and simple, instant and on-site detection methods are called rapid detectio...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N21/64G01N21/01
CPCG01N21/01G01N21/6486
Inventor 张东旭戴皓正黄绍磊张剑滨张雅王进翁祖星宋浏伟张师音葛胜祥张军夏宁邵
Owner XIAMEN UNIV
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