Fermentation active substance for improving rough skin and sensitive skin and preparation method thereof

A technology for improving skin and skin sensitivity, applied in skin care preparations, medical preparations containing active ingredients, pharmaceutical formulas, etc., to achieve the effect of improving rough skin

Active Publication Date: 2021-04-30
广州市万千粉丝化妆品有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there is no example of co-fermenting tea seed protein polypeptide obtained from tea seed meal with soybean meal to obtain active substances that improve skin surface roughness and skin sensitivity

Method used

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  • Fermentation active substance for improving rough skin and sensitive skin and preparation method thereof
  • Fermentation active substance for improving rough skin and sensitive skin and preparation method thereof
  • Fermentation active substance for improving rough skin and sensitive skin and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] Embodiment 1, the preparation method of fermentation active matter of the present invention

[0026] S1. Mix tea seed meal powder and deionized water at a weight ratio of 1:20, adjust the pH to 6.0-8.0, add bromelain with 2% weight of tea seed meal powder, react in a water bath at 55°C for 90 minutes, and obtain tea after sterilization Seed meal enzymatic hydrolysis solution;

[0027] S2, add 0.2mol / L (NH 4 ) 2 SO 4 1. Extract at 25°C for 150 minutes, use 0.1mol / L NaOH to adjust the pH value to the isoelectric point, centrifuge at 8000r / min for 10 minutes, remove the supernatant, desalt the precipitate through dialysis, and obtain the tea seed protein polypeptide after freeze-drying;

[0028] S3. Transfer the above-mentioned tea seed protein polypeptide to a fermenter containing a fermentation medium, add soybean meal powder, and inoculate 2% of Candida utilis, at a temperature of 28°C, an air flow of 8 L / min, and a stirring speed of 300r. Ferment for 48 hours under...

Embodiment 2

[0029] Embodiment two, the preparation method of fermentation active substance of the present invention

[0030] S1. Mix tea seed meal powder and deionized water in a weight ratio of 1:15, adjust the pH to 6.0-8.0, add bromelain with 1% weight of tea seed meal powder, react in a water bath at 55°C for 100 minutes, and obtain tea seeds after sterilization meal enzymatic solution;

[0031] S2, add 0.1mol / L (NH 4 ) 2 SO 4 1. Extract at 25°C for 120 minutes, use 0.1mol / L NaOH to adjust the pH value to the isoelectric point, centrifuge at 10,000r / min for 10 minutes, remove the supernatant, desalt the precipitate through dialysis, and obtain the tea seed protein polypeptide after freeze-drying;

[0032] S3. Transfer the above-mentioned tea seed protein polypeptide to a fermenter containing a fermentation medium, add soybean meal powder, and inoculate 2% of Candida utilis, at a temperature of 28°C, an air flow of 10L / min, and a stirring speed of 250r. Ferment for 72 hours under t...

Embodiment 3

[0033] Embodiment three, the preparation method of fermentation active substance of the present invention

[0034] S1. Mix tea seed meal powder and deionized water at a weight ratio of 1:30, adjust the pH to 6.0-8.0, add 1.5% bromelain by weight of tea seed meal powder, react in a water bath at 55°C for 100 minutes, and obtain tea after sterilization Seed meal enzymatic hydrolysis solution;

[0035] S2, add 0.2mol / L (NH 4 ) 2 SO 4 . Extract at 25°C for 240 minutes, use 0.1mol / L NaOH to adjust the pH value to the isoelectric point, centrifuge at 10,000r / min for 10 minutes, remove the supernatant, desalt the precipitate through dialysis, and obtain the tea seed protein polypeptide after freeze-drying;

[0036] S3. Transfer the above-mentioned tea seed protein polypeptide to a fermenter containing a fermentation medium, add soybean meal powder, and inoculate 2% of Candida utilis, at a temperature of 28°C, an air flow of 6L / min, and a stirring speed of 350r Ferment for 48 hours ...

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Abstract

The invention relates to a fermented active substance for improving rough skin and sensitive skin and a preparation method thereof. The active substance uses a specific protease to enzymatically hydrolyze the tea seed dregs of an agricultural by-product to obtain a tea seed protein polypeptide, and then combines the tea seed protein polypeptide with the Soybean meal is obtained under fermentation inoculated with specific strains. Tests have proved that after the 4th week of using the active substance, the roughness of the skin surface is significantly reduced, the symptoms of skin sensitivity are obviously relieved, and it has a significant effect on improving the roughness of the skin surface and skin sensitivity.

Description

technical field [0001] The invention relates to the technical field of cosmetics, in particular to a fermented active substance for improving rough and sensitive skin and a preparation method thereof. Background technique [0002] One of the inherent characteristics of skin tissue is skin texture, which is accompanied by human beings at birth. It is composed of undulating skin grooves and skin ridges, and most of them are relatively fixed polygons. However, the skin that is often exposed to the outside will be stimulated by the external environment, such as computer radiation, dust in the air, etc., and will be continuously damaged. Reduced, the surface area continues to expand, so the skin surface becomes rough. At the same time, oily skin has clogged pores due to excessive secretion of sebaceous glands, and the formed horn plugs cannot be discharged, resulting in enlarged pores and rough skin. [0003] Sensitive skin means that the skin is very easy to react to external ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K8/9789A61K8/9728A61K8/64A61Q19/00
CPCA61K8/645A61K2800/805A61K2800/85A61Q19/00A61Q19/005A61K8/9728A61K8/9789
Inventor 林杰彬刘燕
Owner 广州市万千粉丝化妆品有限公司
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