Self-driven electrowetting valve, paper-based microfluidic chip and immunodetection device

Abstract

The invention discloses a self-driven electrowetting valve, a paper-based microfluid chip and an immunodetection device. The self-driven electrowetting valve comprises an integrated barrier layer anda friction nano-generator, wherein to-be-passed liquid drops located on one side of the barrier layer is connected to an electrode, the electrode is connected to the output of the friction nano-generator, and the output voltage of the friction nano-generator is loaded to the electrode to drive the to-be-passed liquid drops to spread on the barrier layer and pass through the barrier layer, so thatself-driven electrowetting is realized. According to the invention, the output of the friction nano-generator is directly used for electrowetting driving of to-be-passed liquid drops above the barrierlayer; a traditional direct-current or alternating-current power supply drive and a complex management circuit are not needed; the circuit structure is simple, energy consumption is low, meanwhile, the self-driven advantage is achieved; the two to-be-detected liquid drops are connected to the output of the friction nano-generator through the electrode, and simultaneous dripping can be achieved; and for immunodetection reaction, accurate control over reaction time can be achieved.

Description

technical field [0001] The disclosure belongs to the field of nano new energy technology and immune detection technology, and relates to a self-driven electrowetting valve, a paper-based microfluidic chip and an immune detection device. Background technique [0002] As an emerging technology, paper-based microfluidic chips can be used for immunoassays. However, several reagents often need to be added during the test, and the time interval between adding each reagent may affect the final test results. [0003] Electro-wetting (EW, Electro-wetting) refers to changing the wettability of a droplet on a substrate by changing the voltage between the droplet and an insulating substrate, that is, changing the contact angle to cause deformation and displacement of the droplet. The so-called wetting refers to the process in which one fluid on the surface of a solid is replaced by another fluid. The liquid can spread on the solid surface, and the solid-liquid contact surface tends to ...

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