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Application of infantile indigestion removing and cough relieving preparation to preparation of medicines for treating indigestion and fever and preparation method of preparation

A technology for eliminating stagnation and relieving cough and preparations for children, which is applied in the field of medicine and can solve problems such as no clear diagnosis, palliative treatment but not the root cause, and large side effects

Inactive Publication Date: 2020-08-14
LUNAN PHARMA GROUP CORPORATION
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] In western medicine, the symptoms of food accumulation fever syndrome can be found in many diseases such as "fever", "mesenteric lymphadenitis", "obstructed eating difficulty", but there is no clear diagnosis, and antipyretic analgesics are mostly used for symptomatic treatment. The results are not satisfactory, and the side effects are relatively low. Large, not suitable for all children, treating the symptoms but not the root cause, the condition is poorly controlled

Method used

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  • Application of infantile indigestion removing and cough relieving preparation to preparation of medicines for treating indigestion and fever and preparation method of preparation
  • Application of infantile indigestion removing and cough relieving preparation to preparation of medicines for treating indigestion and fever and preparation method of preparation

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0062] Example 1 Preparation of Xiaoer Xiaoji Zhike Capsules

[0063] Hawthorn 0.07kg Betel nut 0.18kg Loquat leaf 0.07kg

[0064] Citrus aurantium 0.07kg Radix 0.14kg Whole melon 0.075kg

[0065] Tinglizi 0.14kg Bellflower 0.09kg Forsythia 0.14kg

[0066] Cicada slough 0.06kg

[0067] A. Add fried hawthorn, betel nut, honey-roasted loquat leaves, citrus aurantium, fried radish seeds, melons, fried Tinglizi, platycodon, forsythia, cicada slough and decoct twice, and add 8 times the amount of water for decocting for the first time For 1.5 hours, add 9 times the amount of water for the second time and decoct for 1.5 hours, combine the decoction liquid, filter, concentrate under reduced pressure to an extract with a density of 1.24 at 50°C, add 95% ethanol for alcohol precipitation, and make the ethanol content reach 70% , refrigerated for 48 hours, filtered to obtain the filtrate, and set aside;

[0068] B. When the filtrate of step A is concentrated under reduced pressure t...

Embodiment 2

[0070] Example 2 Preparation of Xiaoer Xiaoji Zhike Granules

[0071] Hawthorn 0.05kg Betel nut 0.2kg Loquat leaf 0.05kg

[0072] Citrus aurantium 0.2kg Raspberry 0.8kg Whole melon 0.268kg

[0073] Tinglizi 0.08kg Bellflower 0.15kg Forsythia 0.08kg

[0074] Cicada slough 0.1kg

[0075] A. Add fried hawthorn, betel nut, honey-roasted loquat leaves, citrus aurantium, fried radish seeds, melons, fried Tinglizi, platycodon, forsythia, cicada slough and decoct twice, and add 9 times the amount of water for decocting for the first time For 2.5 hours, add 10 times the amount of water for the second time and decoct for 2 hours, combine the decoction liquid, filter, concentrate under reduced pressure to an extract with a density of 1.20 at 50°C, add 95% ethanol for alcohol precipitation, and make the ethanol content reach 80% , refrigerated for 48 hours, filtered to obtain the filtrate, and set aside;

[0076] B. When the filtrate of step A is concentrated under reduced pressure to...

Embodiment 3

[0078] Example 3 Preparation of Xiaoer Xiaoji Cough Syrup

[0079] Hawthorn 0.19kg Betel nut 0.06kg Loquat leaf 0.19kg

[0080] Citrus aurantium 0.06kg Raisin 0.14kg Whole melon 0.077kg

[0081]Tinglizi 0.14kg Bellflower 0.09kg Forsythia 0.14kg

[0082] Cicada slough 0.06kg

[0083] A. Add fried hawthorn, betel nut, honey-roasted loquat leaves, citrus aurantium, fried radish seeds, melon, fried Tinglizi, platycodon, forsythia, cicada slough and decoct twice, and add 10 times the amount of water for decocting for the first time For 1.5 hours, add 8 times the amount of water for the second time to decoct for 2.5 hours, combine the decoction liquid, filter, concentrate under reduced pressure to an extract with a density of 1.23 at 50°C, add 95% ethanol for alcohol precipitation, and make the ethanol content reach 60% , refrigerated for 24 hours, filtered to obtain the filtrate, and set aside;

[0084] B. When the filtrate of step A is concentrated under reduced pressure to 50...

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Abstract

The invention discloses an application of an infantile indigestion removing and cough relieving preparation to preparation of medicines for treating indigestion and fever and a preparation method of the preparation, and belongs to the field of medicines. The infantile indigestion removing and cough relieving preparation is prepared from 10 medicines including fructus crataegi, betel nut, fructus aurantill immaturus, folium eriobotryae, fructus trichosanthis, fructus forsythia, semen raphani, semen lepidii, periostracum cicada and radix platycodonis. The preparation has the effects of clearingheat, purging the lung, removing indigestion and relieving cough. The infantile indigestion removing and cough relieving preparation has the function of bringing down fever and promoting pepsinogen secretion, is beneficial to food digestion and absorption, can achieve the therapeutic effects of removing indigestion and reducing fever, regulating the spleen and stomach and treating both symptoms and root causes for patients with fever caused by indigestion, and provides a new choice for clinical medication.

Description

technical field [0001] The invention relates to the application and preparation method of Xiaoer Xiaoji antitussive preparation, in particular to the application and preparation method of Xiaoer Xiaoji antitussive preparation in the preparation of medicines for treating fever syndrome, and belongs to the field of medicine. Background technique [0002] With the development of society and the improvement of living conditions, people's diet structure is becoming more and more "eutrophic", and the incidence of gastrointestinal heat accumulation is increasing year by year. Just as it is said in "Young You Ji Syndrome and Treatment of Food Injury" that "Children's disease is caused by food injury the most", for children, food accumulation has indeed become a common clinical pathogenic factor in pediatrics, and plays an important role in children's morbidity. Children belong to the body of pure yang, the viscera are delicate, the liver is often surplus, and the spleen is often ins...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/889A61P29/00A61P1/14A61P31/14A61P11/00A61P31/16A61P31/20A61K35/64
CPCA61K36/734A61K36/889A61K36/73A61K36/752A61K36/31A61K36/428A61K36/346A61K36/634A61K35/64A61P29/00A61P1/14A61P31/14A61P11/00A61P31/16A61P31/20A61K2236/331A61K2236/39A61K2236/51A61K2236/53A61K2300/00
Inventor 张贵民关永霞范建伟
Owner LUNAN PHARMA GROUP CORPORATION
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