Use of methallyl trisulfide in the preparation of medicines for treating acute lung injury
A technology of methallyl trisulfide and acute lung injury, applied in the field of medicine, can solve the problem of no specific prevention and treatment drugs for ALI, and achieve the effect of improving pathological manifestations, reducing and reducing pulmonary edema
- Summary
- Abstract
- Description
- Claims
- Application Information
AI Technical Summary
Problems solved by technology
Method used
Image
Examples
Embodiment 1
[0028] Chemical reagent and instrument
[0029] AMTS (CAS Number: 34135-85-8) Purchased from Hubei Xinkang Pharmaceutical Chemical Co., Ltd., LPS is purchased from Sigma, BCA kit purchase of self-competition Mo Fei Shier Technology Company, TNF-α, IL-1β kit purchase Since Wuhan Yunclong Technology Co., Ltd., corn oil is purchased by the market. Desktop frozen centrifuge Eppendorf (5804R), pipe gun (Eppendorf), Rward R540 enhanced small animal anesthesia machine.
[0030] Animal experiment
[0031] Take 60 ICR male mice, weight 18-22g, purchased from Jinan Pengyue Experimental Animal Breeding Co., Ltd., animal raised in IVC animal breeding, free drinking water. After a week of adaptive feeding, randomly divided into blank control group, model control group, AMTS low dose intervention group (25 mg / kg.bw), dose intervention group (50 mg / kg.bw), AMTS high dose intervention group (100 mg / kg.bw), 12 animals per group. The AMTS intervention group was allowed to give an equal amount...
Embodiment 2
[0053] A soft capsule containing acute lung damage containing methyl allyl trithio ether, which includes: methyl allyl trithio ether, excipient, soft adhesive case, and directly packaged by a soft capsule compression process. Dosage: Oral, 2.78 ~ 11.1mg / kg.bw, can be discreted according to the actual condition.
Embodiment 3
[0055] A dripping pill containing acute lung damage containing methyl allyl trithio ether, which includes: methylene trionyl ether, matrix, direct bracelet through dripping process. Dosage: Oral, 2.78 ~ 11.1mg / kg.bw, can be discreted according to the actual condition.
PUM
Abstract
Description
Claims
Application Information
- R&D Engineer
- R&D Manager
- IP Professional
- Industry Leading Data Capabilities
- Powerful AI technology
- Patent DNA Extraction
Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.
© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com