Method for establishing disposal index DI estimation model

A technology for estimating models and establishing methods, applied in health index calculation, complex mathematical operations, computer-aided medical procedures, etc., which can solve the problems of long time, cumbersome disposal index DI test methods, and high cost
CN112365979APending Publication Date: 2021-02-12RUIJIN HOSPITAL AFFILIATED TO SHANGHAI JIAO TONG UNIV SCHOOL OF MEDICINE +1
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
RUIJIN HOSPITAL AFFILIATED TO SHANGHAI JIAO TONG UNIV SCHOOL OF MEDICINE
Publication Date
2021-02-12

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Abstract

The invention relates to a method for establishing a DI (Disposal Index) estimation model. The method comprises the following steps of: taking young obese crowds as modeling crowds, evaluating the relationship between Log (DI) and each index of a baseline in the modeling crowds by utilizing correlation analysis, screening DI-related variables in the modeling crowds according to single-factor regression analysis to enter multiple linear regression analysis, screening out four variables of fasting blood glucose FPG, fasting insulin FINS level, alanine aminotransferase ALT and systolic pressure SBP, and inputting the four variables into an equation, and establishing the DI estimation equation. The estimation model has a high degree of correlation with actually measured DI in modeling crowds and verification crowds, and has good discrimination and calibration degrees.
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Description

technical field

[0001] The invention belongs to the field of diabetes prediction indicators, in particular to a method for establishing a disposition index DI estimation model. Background technique

[0002] Type 2 diabetes is a common complication of obesity. Epidemiological studies show that as of 2013, the prevalence of diabetes in my country was as high as 10.9%, and the number of patients reached 116.4 million. Insulin secretion dysfunction and decreased insulin sensitivity are two main factors in the occurrence of type 2 diabetes. The latest prospective clinical study of our center found that the occurrence of diabetes in the Chinese population is attributed to: insulin resistance (24.4%) caused by obesity, and β-cell dysfunction (12.4%). Therefore, insulin sensitivity and insulin secretion function are important indicators to measure islet cell function and blood sugar regulation ability.

[0003] Bergman et al. analyzed the multi-point plasma glucose and insulin co...

Claims

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