Antibody composition for detecting treatment effect of multiple myeloma as well as kit and application thereof

A technology of multiple myeloma and antibody composition, applied in the field of biomedicine, can solve problems such as unseen problems, achieve convenient operation, reduce medical burden, and achieve objective and accurate results
CN112698037AActive Publication Date: 2021-04-23BEIJING JISHUITAN HOSPITAL
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
BEIJING JISHUITAN HOSPITAL
Publication Date
2021-04-23

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Abstract

The invention discloses an antibody composition for detecting the treatment effect of multiple myeloma as well as a kit and application thereof, and the antibody composition scheme provided by the invention comprises a flow antibody combination which is never clinically used for detecting peripheral blood tumor plasma cells in the past, stipulates the number of detected cells and standard operation steps, and defines the degree to which the sensitivity needs to be reached. Peripheral blood is adopted to replace a bone marrow specimen, the pain of a patient receiving bone marrow puncture can be greatly relieved, peripheral plasma cell detection can be repeatedly operated, flexibility and convenience are achieved, the workload of clinicians is greatly relieved, and efficiency is improved.
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Description

technical field

[0001] The invention belongs to the technical field of biomedicine, and relates to an antibody composition for detecting the therapeutic effect of multiple myeloma, a kit and application thereof. Background technique

[0002] Multiple myeloma is a malignant hematological tumor, and patients cannot be cured, requiring continuous chemotherapy for at least 2 years or even long-term continuous treatment. Patients receiving chemotherapy need to undergo bone marrow aspiration every two months in order to comprehensively evaluate the treatment effect in combination with other indicators. Currently, the internationally recognized indicators for evaluating curative effect include blood immunoglobulin quantification, urine light chain quantification, the proportion of plasma cells in bone marrow aspiration, and imaging examinations. Among them, bone marrow puncture is a kind of invasive examination, which needs to be performed under anesthesia. The patient has certain...

Claims

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