Tumor mutation load detection intelligent system based on 5G and block chains and method

Abstract

The invention belongs to the technical field of intelligent tumor and gene detection, and particularly relates to an intelligent tumor mutation load detection system based on 5G and block chains and a method. The intelligent tumor mutation load detection system comprises a workbench. The inner wall at the bottom of the workbench is rotationally connected with a first rotary shaft and a second rotary shaft. The top of the first rotary shaft extends to the top of the workbench and is connected with a first loading disc. The tumor mutation load detection intelligent system of the present invention is simple in structure. A plurality of gene detection reagents can be held on the first loading disc at the same time, and moved beneath a detection probe through intermittent rotation of the first loading disc and a second loading disc. The gene detection reagents are detected without manual operation during detection process. a large number of gene detection reagents can be detected to obtain accurate data, in addition, the gene detection reagents meeting the standard can be conveyed to a low-temperature storage box in time for storage after detection is finished. By 5G and block chain technology, the information on a control panel is transmitted to a doctor reception for recording and observation.

Description

technical field

[0001] The present invention relates to the field of tumor and gene detection intelligence technology, in particular to an intelligent system and method for tumor mutation load detection based on 5G and blockchain. Background technique

[0002] Tumors are diseases caused by mutations in the genome. Immune checkpoint inhibitors have opened up a new era of tumor therapy, but due to the lack of suitable clinical molecular markers, PD-1 / PD-L1 (programmed cell death receptor-1, programmed death-1, PD-1; programmed death-1; The beneficiary population of cell death ligand-1 (programmed cell death ligand 1, PD-L1) drug cannot be efficiently screened, and the screening rate is only 20%-30%. Tumor mutation burden (TMB) is an index that reflects the degree of total gene mutation in tumor cells, usually expressed by the total number of tumor somatic mutations contained in each million bases (Mb) of the tumor genome region. Different types of tumors and different groups...

Examples

Embodiment 1

[0052] refer to Figure 1-14 , an intelligent system for tumor mutation load detection based on 5G and blockchain, including a workbench 1, the bottom inner wall of the workbench 1 is rotatably connected with a first rotating shaft 4 and a second rotating shaft 5, and the top of the first rotating shaft 4 extends to the workbench 1 and is fixedly connected with the first loading tray 2, the top of the second rotating shaft 5 extends to the top of the workbench 1 and is fixedly connected with the second loading tray 3, the tops of the first loading tray 2 and the second loading tray 3 are equidistant A plurality of placement slots 20 are arranged, the inner wall of the bottom of the workbench 1 is fixedly connected with the drive motor 6, the output shaft of the drive motor 6 is fixedly connected with the disc 7, and the top of the disc 7 is fixedly connected with a protruding rod on the side deviated from the center of the circle 8. The outer wall of the first rotating shaft 4...

Embodiment 2

[0067] Embodiment two: if Figure 15 As shown in -17, the intelligent system for tumor mutation load detection based on 5G and blockchain, the difference between this embodiment and Embodiment 1 is that the top of the second rotating shaft 5 is fixedly connected with a block 49, and the bottom of the second loading tray 3 The center of the circle is provided with a draw-in groove 50, and the block 49 extends into the draw-in groove 50. On the top of the workbench 1, a plurality of electric telescopic rods 51 are arranged in a circular equidistant manner with the second rotating shaft 5 as the center of the circle. The bottom of the plurality of electric telescopic rods 51 Both ends are slidingly connected to the bottom of the second loading tray 3, the top of the workbench 1 is fixedly connected with a hydraulic cylinder 52, the piston rod of the hydraulic cylinder 52 touches the second loading tray 3, and the top of the workbench 1 is fixedly connected with a cryogenic Storag...

technical field

[0001] The present invention relates to the field of tumor and gene detection intelligence technology, in particular to an intelligent system and method for tumor mutation load detection based on 5G and blockchain. Background technique

[0002] Tumors are diseases caused by mutations in the genome. Immune checkpoint inhibitors have opened up a new era of tumor therapy, but due to the lack of suitable clinical molecular markers, PD-1 / PD-L1 (programmed cell death receptor-1, programmed death-1, PD-1; programmed death-1; The beneficiary population of cell death ligand-1 (programmed cell death ligand 1, PD-L1) drug cannot be efficiently screened, and the screening rate is only 20%-30%. Tumor mutation burden (TMB) is an index that reflects the degree of total gene mutation in tumor cells, usually expressed by the total number of tumor somatic mutations contained in each million bases (Mb) of the tumor genome region. Different types of tumors and different groups...

Examples

Embodiment 1

[0052] refer to Figure 1-14 , an intelligent system for tumor mutation load detection based on 5G and blockchain, including a workbench 1, the bottom inner wall of the workbench 1 is rotatably connected with a first rotating shaft 4 and a second rotating shaft 5, and the top of the first rotating shaft 4 extends to the workbench 1 and is fixedly connected with the first loading tray 2, the top of the second rotating shaft 5 extends to the top of the workbench 1 and is fixedly connected with the second loading tray 3, the tops of the first loading tray 2 and the second loading tray 3 are equidistant A plurality of placement slots 20 are arranged, the inner wall of the bottom of the workbench 1 is fixedly connected with the drive motor 6, the output shaft of the drive motor 6 is fixedly connected with the disc 7, and the top of the disc 7 is fixedly connected with a protruding rod on the side deviated from the center of the circle 8. The outer wall of the first rotating shaft 4...

Embodiment 2

[0067] Embodiment two: if Figure 15 As shown in -17, the intelligent system for tumor mutation load detection based on 5G and blockchain, the difference between this embodiment and Embodiment 1 is that the top of the second rotating shaft 5 is fixedly connected with a block 49, and the bottom of the second loading tray 3 The center of the circle is provided with a draw-in groove 50, and the block 49 extends into the draw-in groove 50. On the top of the workbench 1, a plurality of electric telescopic rods 51 are arranged in a circular equidistant manner with the second rotating shaft 5 as the center of the circle. The bottom of the plurality of electric telescopic rods 51 Both ends are slidingly connected to the bottom of the second loading tray 3, the top of the workbench 1 is fixedly connected with a hydraulic cylinder 52, the piston rod of the hydraulic cylinder 52 touches the second loading tray 3, and the top of the workbench 1 is fixedly connected with a cryogenic Storag...

Images