Tumor mutation load detection intelligent system based on 5G and block chains and method
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- 西康软件有限责任公司
- Publication Date
- 2021-04-27
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Abstract
Description
technical field
[0001] The present invention relates to the field of tumor and gene detection intelligence technology, in particular to an intelligent system and method for tumor mutation load detection based on 5G and blockchain. Background technique
[0002] Tumors are diseases caused by mutations in the genome. Immune checkpoint inhibitors have opened up a new era of tumor therapy, but due to the lack of suitable clinical molecular markers, PD-1 / PD-L1 (programmed cell death receptor-1, programmed death-1, PD-1; programmed death-1; The beneficiary population of cell death ligand-1 (programmed cell death ligand 1, PD-L1) drug cannot be efficiently screened, and the screening rate is only 20%-30%. Tumor mutation burden (TMB) is an index that reflects the degree of total gene mutation in tumor cells, usually expressed by the total number of tumor somatic mutations contained in each million bases (Mb) of the tumor genome region. Different types of tumors and different groups...