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Storage device of detection reagent for detecting BRAF gene mutation

A storage device and detection reagent technology, applied in the directions of transportation and packaging, types of packaging items, special packaging items, etc., can solve the problems of inability to provide protection for reagent tubes, thermal insulation efficiency, and difficulty in guaranteeing the effect, so as to improve the efficiency of liquid exchange and improve the Stability and the effect of improving cooling capacity

Active Publication Date: 2021-06-04
THE AFFILIATED HOSPITAL OF QINGDAO UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] The BRAF gene is located on chromosome 7 and is an oncogene. Among them, V600E is the most mutated site in the BRAF gene, which is often found in melanoma, non-Hodgkin's lymphoma, colorectal cancer, thyroid cancer, non-small cell Mutations in lung cancer are currently most commonly used in the auxiliary diagnosis of thyroid cancer. Corresponding detection reagents are required for genetic testing, and the reagents need to be stored for use. At present, the storage of reagents is often placed directly in a refrigerator. The insulation efficiency and effect are difficult to guarantee, and the reagent tube cannot be protected during transportation

Method used

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  • Storage device of detection reagent for detecting BRAF gene mutation
  • Storage device of detection reagent for detecting BRAF gene mutation
  • Storage device of detection reagent for detecting BRAF gene mutation

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Embodiment Construction

[0025] see Figure 1~4 , in an embodiment of the present invention, a reagent storage device for detecting BRAF gene mutation detection includes a storage box 1, a circulation pipeline 2, a refrigeration compartment 3, a circulation pump 4, a liquid replacement and cooling assembly 5, and a reagent tube placement assembly 7, wherein , the inside of the storage box 1 is fixed with a circulation pipeline 2, the circulation pipeline 2 includes an upper horizontal pipeline and a lower horizontal pipeline, wherein the lower horizontal pipeline is embedded with a refrigerating chamber 3, and the inside of the circulation pipeline 2 The cooling liquid is driven by the circulation pump 4 to circulate;

[0026] At least two groups of liquid exchange and cooling components 5 are sequentially connected to the upper horizontal pipeline along the cooling liquid flow direction, and the liquid exchange and cooling components 5 can provide cooling liquid at a suitable temperature for the reag...

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Abstract

The invention discloses a storage device of a detection reagent for detecting BRAF gene mutation. Cooling liquid serves as a temperature maintaining medium of a reagent tube, the stability of temperature maintaining of the reagent tube can be effectively improved, the cooling liquid in a liquid changing and cooling assembly can be monitored in real time through a temperature sensor, and during synchronous liquid changing, through suction of a miniature suction pump, cold cooling liquid in a circulating pipeline can be supplemented into a liquid changing tank, and part of the cooling liquid in the liquid changing tank is discharged, so that the cooling capacity of the cooling liquid in the liquid changing tank can be stably improved and reaches the initial level; and besides, when the cooling liquid in the circulating pipeline enters the liquid changing tank, a push plate can be pushed to move and can push the liquid out of the liquid changing tank, and a gap is formed between the top of the push plate and the top of the liquid changing tank, so that the push plate can be automatically restored after the liquid changing is completed, the liquid changing efficiency is improved, the effectiveness of the reagent is ensured, and the detection accuracy is further ensured.

Description

technical field [0001] The invention relates to the technical field of reagent storage, in particular to a reagent storage device for detecting BRAF gene mutation. Background technique [0002] The BRAF gene is located on chromosome 7 and is an oncogene. Among them, V600E is the most mutated site in the BRAF gene, which is often found in melanoma, non-Hodgkin's lymphoma, colorectal cancer, thyroid cancer, non-small cell Mutations in lung cancer are currently most commonly used in the auxiliary diagnosis of thyroid cancer. Corresponding detection reagents are required for genetic testing, and the reagents need to be stored for use. At present, the storage of reagents is often placed directly in a refrigerator. The insulation efficiency and effect are difficult to guarantee, and the reagent tubes cannot be protected during transportation. [0003] Therefore, it is necessary to provide a storage device for detecting BRAF gene mutation detection reagents to solve the problems r...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): B65D25/02B65D81/18B65D81/05
CPCB65D25/02B65D81/18B65D81/05
Inventor 王萍付浴东于清邓玉杰王青
Owner THE AFFILIATED HOSPITAL OF QINGDAO UNIV
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