Application of formononetin in preparation of medicine for treating or/and preventing depression
A technology of formononetin and depression, applied in the field of biomedicine, can solve the problems of central nervous system inflammation and depression with low toxic and side effects, lack of effective treatment, and significant side effects, etc., achieving small adverse reactions and low cost , less toxic and side effects
Active Publication Date: 2022-05-31
JINAN UNIVERSITY
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Problems solved by technology
However, the side effects of these drugs are more significant
[0005] It can be seen that the existing western medicine treatment scheme lacks drugs that can effectively treat central nervous system inflammation and depression and have low toxic and side effects
Method used
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Effect test
Embodiment 1
[0049] Choose 30 healthy male SD rats, the age is about 6 weeks, and the body weight is between (200 ± 20) g. at clean level
Embodiment 2
[0054] The mental state, fur color and lustre, voluntary activity etc. of the rat were observed every day. From 1 day before modeling, every day
Embodiment 3
[0058] The depression-like behaviors of the experimental animals in the Control group, LPS group and LPS+F group of Example 1 were observed. in a quiet environment
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The application belongs to the technical field of biomedicine, and in particular relates to the application of formononetin in the preparation of drugs for treating or / and preventing depression. The first aspect of the application discloses the application of formononetin in the preparation of drugs for the treatment or / and prevention of depression; the second aspect of the application discloses the application of formononetin in the preparation of drugs for the treatment or / and prevention of central nervous system inflammation in the application. The formononetin of the present application is an antidepressant and anti-neuritis drug with strong safety and few adverse reactions.
Description
The application of formononetin in the preparation of medicine for treating or / and preventing depression technical field The application belongs to biomedical technology field, relate in particular to formononetin in preparation treatment or / and prevention of depression application in medicines. Background technique [0002] Depression is a common mental system disease, and cancer and AIDS are called the three major diseases. Clinically, its With persistent fatigue, slow response, low mood, loss of appetite, loss of speech, and weight loss, severe cases will never feel dull. Delusions, hallucinations, or unrealistic behaviors are the main symptoms, and have both Typical features of high morbidity, mortality and morbidity. With the gradual development of economy and society, people's life rhythm increases, People are also under increasing stress, resulting in an increase in the incidence of depression year by year. [0003] Currently, the etiology and pathogenesis o...
Claims
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IPC IPC(8): A61K31/352A61P25/24A61P25/00A61P29/00
CPCA61K31/352A61P25/24A61P25/00A61P29/00
Inventor 陈家旭黄俊卿姚志红郝闻致何亮亮鄢黎朱潇旭王雅平
Owner JINAN UNIVERSITY
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