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Inflammatory brain disease, also referred to as inflammatory disease of the central nervous system (CNS), is a condition where the brain and/or spinal cord become inflamed. Inflammation in the brain causes irritation and swelling of brain tissue or blood vessels. Brain inflammation can occur...
A compound of pyrrolopyridine structure, preparation method and medical use
PendingCN122167421AOrganic active ingredientsSenses disorderPharmaceutical drugMyeloproliferative Disorders
This invention discloses a compound with a pyrrolopyridine structure, its preparation method, and its pharmaceutical uses. This invention provides a novel compound with a pyrrolopyridine structure and a method for synthesizing this series of compounds. Activity studies show that the compound with the pyrrolopyridine structure possesses excellent JAK protein kinase inhibitory activity. Those skilled in the art know that JAK protein kinase plays an important role in the occurrence and development of various diseases, such as various immune diseases, myeloproliferative disorders, and central nervous system inflammatory diseases; inhibiting JAK can treat or alleviate these diseases. Therefore, the compound with the pyrrolopyridine structure provided by this invention has the potential for development into a JAK inhibitor drug and for treating or alleviating diseases by inhibiting JAK.
Owner:NANJING LINGNUO BIOMEDICAL TECH RES INST CO LTD