39 results about "Therapy Object" patented technology

Generally, the present invention provides a device for insertion into a body of a subject being treated to deliver localized x-ray radiation, and a method for use of such a device. The device includes an anode and a cathode, disposed within a vacuum housing. The device further includes a balloon coupled to and circumferentially surrounding the vacuum housing, and a fluid loop for circulating a cooling fluid proximate to the vacuum housing. A method for delivering localized x-ray radiation to an interior passage of a body is also described, including the steps of positioning an x-ray device at the passage to be treated and applying a high voltage to the x-ray producing unit to produce localized x-ray radiation.

This invention provides substituted acylanilide compounds and uses thereof in treating a variety of diseases or conditions in a subject, including, inter alia, a muscle wasting disease and / or disorder or a bone-related disease and / or disorder.

The present invention discloses compounds of Formula (I), or pharmaceutically acceptable salts, esters, or prodrugs thereof:which inhibit RNA-containing virus, particularly the hepatitis C virus (HCV). Consequently, the compounds of the present invention interfere with the life cycle of the hepatitis C virus and are also useful as antiviral agents. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from HCV infection. The invention also relates to methods of treating an HCV infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention. The present invention relates to novel antiviral compounds represented herein above, pharmaceutical compositions comprising such compounds, and methods for the treatment or prophylaxis of viral (particularly HCV) infection in a subject in need of such therapy with said compounds.

The present invention provides a method and a system for treating a bone. The method includes obtaining a bone model representing a bone which is a subject of treatment; obtaining a target bone model to which treatment aims; determining a treatment process (e.g., a necessary assisting member) which is to be performed on the bone based on the bone model and the target bone model; and performing a surgical operation using the determined treatment process. The present invention provides a computer program for performing such a method.

This invention relates to a low cost rapid response diagnostic system to determine cortisol levels in patients selected as potential candidates for GCR (glucocorticoid receptor) antagonist therapy utilizing a GCR antagonist, such as ORG 34517. The rapid, sensitive, and inexpensive test can be used to determine patients who have non-normal cortisol production or disordered circadian rhythms as a method for selecting subjects for GCR antagonist therapy for whom it is likely to have beneficial and / or therapeutic effects, and can also be used to monitor changes in cortisol levels in response to treatment.

The invention relates to methods of treating shock in a subject by administering a pharmaceutically effective amount of androstenetriol (AET), androstenediol (AED) or derivatives thereof to a subject suffering from or exhibiting the symptoms of shock. In one particular embodiment, the subject is suffering from hemorrhagic shock. The invention also relates to methods of preventing shock in a subject at risk suffering from shock by administering a pharmaceutically effective amount of androstenetriol or a derivative thereof to the subject, prior to or immediately at the onset of the first symptoms of shock. In one particular embodiment, the subject is at risk suffering from hemorrhagic shock.

The invention discloses an accurate human face acupuncture point locating and acupuncture and moxibustion prescription learning method. Partial human face characteristic analysis and a pattern and nerve identifying algorithm are utilized to determine all organs and the characteristic portions of the human face, a coordinate origin is determined, a virtual simulation face locating coordinate system is established, data information of different acupuncture experts to acupuncture point location is collected, acupuncture point data values with the best accuracy can be achieved through acupuncture location consistency information fusion algorithm, a knowledge base for face disease acupuncture points and acupuncture and moxibustion prescription can be established, and face disease acupuncture point location, acupuncture and mosibustion prescription learning and grade evaluation can be achieved in a virtual and simulated mode. Furthermore, automatic location can be carried out to a new treatment object. The accurate human face acupuncture point locating and acupuncture and moxibustion prescription learning method can improve acupuncture point location fusion error of the different acupuncture and moxibustion experts to the point-by-point variable accuracy, effectively combines the characteristics of the acupuncture point locating measurement values of the different experts and improves the utilizing efficiency of measurement information.

The physical therapy tools, systems, kits and methods described herein may be used to apply gentle, passive and progressive amounts of pressure (including numerous repetitions of small movements) to achieve therapeutic mobilization of a spinal joint. The tools described herein may include a plurality of pads and actuators, where the pressure within each actuator is controlled so that a continuously varying pressure may be applied to mimic the pressure applied by human hands. These tools may also include a controller and one or more user inputs. The physical therapy tools may be operated at different operating modes (e.g., continuously varying pressure modes, step-pulse high frequency modes, step-pulse low frequency modes) for treating a subject's spine, and may be part of a system or kit. Methods of treating a subject using these physical therapy tools are also described herein.

The present invention relates to diseases caused by prion proteins, Novel composite peptide compounds are disclosed which comprise two or more peptides or peptide fragments optionally linked to a backbone and the peptides or peptide fragments are spatially positioned relative to each other so that they together form a non-linear sequence which mimics the tertiary structure of one or more PrPSc-specific epitopes as evidenced by the test described herein. The use of such conjugates as immunogens for the production of antibodies that specifically bind to the pathogenic form of a prion protein is revealed. Other uses of the composite peptide compounds are also disclosed, such as use in diagnostic assays, production of antibodies and uses as vaccine immunogens for the prophylactic protection and therapeutic treatment of subjects against transmissible prion disease.

A radiation therapy system produces a treatment beam that is detected by an electronic portal imaging device (EPID) after it passes through the subject being treated. A chopper wheel modulates low energy components of the beam while leaving the higher energy components substantially unmodulated. Modulated components in the image signals produced by the EPID are detected and used to produce portal images.

A method for the prevention of and therapy for radiation pneumonitis, dermatitis, soft tissue fibrosis and central nervous system toxicity in patients undergoing therapeutic radiation. In addition, the invention provides for pre-treatment of those responding to nuclear bio terrorism or other nuclear or radiological accidents. Thus, with the present invention, subjects may be treated in order to prevent toxicity from nuclear bio terrorism or other nuclear or radiological accidents. More particularly, we have discovered a method for prophylactically treating radiation toxicity in normal tissue of subject comprising administering an anti-radiation toxicity effective amount of a cytokine blocking agent through the subject. More specifically, we have discovered a method for prophylactically treating radiation pneumonitis, dermatitis, soft tissue fibrosis or central nervous system toxicity in a subject comprising administering an anti-radiation pneumonitis, dermatitis, soft tissue fibrosis or central nervous system toxicity effective amount of a cytokine blocking agent to the subject.

Provided is an evaluation method for calculating the quantity of albumin leaking from a blood purifier before purifying the blood of a patient to be treated by using a hollow fiber membrane bundle. Also provided is an evaluation method for calculating values that relate to blood purification conditions and the properties of a blood purifier so as to attain the target albumin leakage quantity. Using statistical procedures, a regression equation for calculating albumin leakage quantity is derived at least on the basis of a first parameter that relates to the blood properties of the subject, a second parameter that relates to the conditions for the purification of the subject's blood, a third parameter that relates to the properties of the blood purifier and the albumin leakage quantity. Then, the quantify of albumin leaking from the blood purifier, said blood purifier being used by the patient to be treated, is calculated using this regression equation. Alternatively, a second parameter and a third parameter that allow the achievement of the target albumin leakage quantity are calculated.

An electric therapy apparatus 1 of the present invention includes: a voltage generating unit 14 for generating a predetermined voltage; a control unit 2 for varying the voltage generated by the voltage generating unit 14 and the output time of the voltage according to a 1 / f fluctuation cycle; and potential therapy conductor terminals 27, 28 for applying the potential from the voltage generating unit 14 to a therapy object, and as a result, the therapy object is prevented from getting acclimatized to stimulation by a constant potential, thereby allowing the human body to be imparted with a relaxing feeling, while sustaining the therapeutic effect of the apparatus.

The embodiment of the invention discloses a method and electric equipment for achieving ultrasound cranial focusing. Under the condition of not performing CT imaging on the head of a to-be-treated object, by simply inputting head nuclear magnetic resonance image data of the object into a target model obtained through training, synthesized head CT image data output by the target model can be obtained, the electric equipment can generate an ultrasonic emission sequence according to a head three-dimensional digital model and a three-dimensional digital model of an ultrasonic transducer array, andthe electric equipment controls the ultrasonic transducer array to emit an ultrasonic wave according to the ultrasonic emission sequence, so that cranial focusing of the head of the to-be-treated object can be achieved, and therapy such as ultrasonic deep brain stimulation or ultrasonic thermal ablation is performed; the risk of cancer caused by irradiation during CT imaging of the to-be-treatedobject is eliminated, the safety of therapy is improved, the therapy steps can also be simplified, the therapy time is greatly shortened, and the therapy cost is reduced.

The invention discloses application of PD-1H agonists to preparing medicine compositions for preventing or treating asthma of objects. The application has the advantages that treatment is carried out by the aid of agonist type PD-1H monoclonal antibodies, accordingly, the quantities of inflammatory cells (eosinophil and lymphocyte in particular) in mouse BALF (bronchoalveolar lavage fluid) are obviously reduced, pulmonary inflammation and myxopoiesis are obviously reduced, and accordingly the fact that PD-1H can be targeted for treating allergic diseases is indicated by results.

Dental treatments and methods, including treating gum disease, using peroxide gel and a viscous antibacterial agent including tetracycline to chemically debride and curettage a treatment area. Treatments and methods include non-surgically scaling and root plaining the treatment area with dental tools such as periodontal scalers and / or curettes during the active period of the chemical debridement. The working surfaces of dental tools can be sharpened for optimal root and tooth surfacing during treatment. Treatment can include instructions for co-therapy by or on behalf of treatment subjects between visits and for maintenance care.

The invention provides the use of a reagent for detecting the expression level of a protein marker in preparing a product for detecting radiotherapy resistance of a pituitary adenoma, as well as a kit and protein marker combination for detecting the radiotherapy resistance of a pituitary adenoma. The present invention can detect the sensitivity of the treated object to radiotherapy of pituitary adenoma by detecting the expression level of protein markers, and analyze whether there is radiotherapy resistance, thereby providing an effective basis for predicting the effect of patients receiving radiotherapy and guiding clinical diagnosis and treatment.

The invention discloses a deep tumor treatment system for photodynamic combined radiotherapy. A low-dosage CT imaging device carries out scanning and imaging on a treated object to obtain information of a spatial position, a size, and a surrounding important structure of a tumor. A deep tumor photodynamic therapeutic device injects a specific X-ray excited photosensitizer into the treated object by intravenous injection and the photosensitizer is collected at a tumor tissue; after X-ray excitation, singlet oxygen is generated; and the deep tumor is processed by photodynamic therapy. A radiotherapy device formulates a radiotherapy scheme meeting a treatment requirement to carry out radiotherapy on the tumor tissue. A deep tumor photodynamic / radiotherapy combined device can carry out photodynamic and radiotherapy processing on the tumor tissue simultaneously. According to the invention, the photodynamic / radiotherapy combined treatment can be carried out on the tumor tissue according to a set parameter and independent photodynamic or radiotherapy treatment can be realized. Therefore, the treatment effect of the deep tumor in the human body can be improved and the exposure dosage on the normal tissue can be reduced effectively.

Provided herein are therapies, and methods using that therapy, in the treatment of one or more of Type 2 diabetes (T2D), obesity, glucose intolerance and insulin resistance or to control weight gain in subjects. In particular, the subject may be candidates for treatment with one or more small molecule anti-diabetic drugs and the therapy may include implanting a population of pancreatic endocrine progenitor cells into the subject, where the cells are allowed to mature in vivo to produce a population.

The invention discloses a medical radiation device and belongs to the radiation therapy field. The medical radiation device includes an image acquisition device, an image processing device, a dose determining device, and an execution device; the image acquisition device is used for acquiring the image data of a radiation therapy object; the image processing device is used for determining a densitydistribution image and regions of interest according to the image data, wherein the regions of interest include a target region and an endangered organ region; the dose determining device is used fordetermining the dose of the radiation device based on the density distribution image and the regions of interest; and the execution device is used for performing treatment on the therapy object according to the dose. The medical radiation device provided by the invention can improve the efficiency and precision of radiation therapy.

The invention discloses an accurate human face acupuncture point locating and acupuncture and moxibustion prescription learning method. Partial human face characteristic analysis and a pattern and nerve identifying algorithm are utilized to determine all organs and the characteristic portions of the human face, a coordinate origin is determined, a virtual simulation face locating coordinate system is established, data information of different acupuncture experts to acupuncture point location is collected, acupuncture point data values with the best accuracy can be achieved through acupuncture location consistency information fusion algorithm, a knowledge base for face disease acupuncture points and acupuncture and moxibustion prescription can be established, and face disease acupuncture point location, acupuncture and mosibustion prescription learning and grade evaluation can be achieved in a virtual and simulated mode. Furthermore, automatic location can be carried out to a new treatment object. The accurate human face acupuncture point locating and acupuncture and moxibustion prescription learning method can improve acupuncture point location fusion error of the different acupuncture and moxibustion experts to the point-by-point variable accuracy, effectively combines the characteristics of the acupuncture point locating measurement values of the different experts and improves the utilizing efficiency of measurement information.

The invention discloses a radiotherapy control method and device, a system, equipment and a storage medium. The method comprises a step of acquiring an interruption record of a treatment subject, wherein the interruption record includes the execution situation of a radiotherapy plan when a radiotherapy process is interrupted, a step of obtaining a radiotherapy compensation plan for compensating the radiotherapy process according to the radiotherapy plan and the execution situation, and a step of controlling the radiotherapy device to perform radiotherapy on the treatment subject according to the radiotherapy compensation plan. By implementing the embodiments of the invention, the radiotherapy compensation plan can be re-acquired for the interrupted radiotherapy process, then the radiotherapy device can be controlled to carry out radiotherapy on the treatment subject according to the radiotherapy compensation plan for, missing radiotherapy after the interruption of the previous radiotherapy process can be compensated to some extent, and the negative impact of the interruption of the radiotherapy process on the radiotherapy of the treatment subject can be reduced.

The present invention provides compositions and methods for treating insulin-dependent diabetes mellitus in a subject comprising administration of a self-vector encoding and expressing human proinsulin.

An intensive intervention and correction method for autistic children, the invention is applied to the intervention and correction of autistic children. It specifically involves the therapist's work flow, class schedule and staffing requirements in the process of intervention and correction of children with autism. Based on the model of long-term memory traces obtained by the memory trace theory, the present invention establishes a strengthened full-time targeted correction course arrangement, so as to ensure that the corrected object guides the purposeful behavior and establishes the training of cognition within the time interval of the correction. The effect is brought into full play to obtain the most optimal correction effect. At the same time, the present invention requires orthodontic therapists to carry out one-on-one teaching for the treatment objects within the time interval of intensive treatment. During this period, the therapists do not receive treatment for other treatment objects, so as to ensure the timeliness and accuracy of the therapist's feedback on the curative effect of the treatment objects. Effectiveness of adjustments to course content.

The present invention relates to CD47 antibodies or fragments thereof binding specifically to the CD47 immunogen for use in preventing or treating tissue injury in states of ischemia or reperfusion in an object whereby the CD47 antibodies or fragments thereof are introduced intravascularly at the or near by the place of ischemia or reperfusion.

This invention relates to a low cost rapid response diagnostic system to determine cortisol levels in patients selected as potential candidates for GCR (glucocorticoid receptor) antagonist therapy utilizing a GCR antagonist, such as ORG 34517. The rapid, sensitive, and inexpensive test can be used to determine patients who have non-normal cortisol production or disordered circadian rhythms as a method for selecting subjects for GCR antagonist therapy for whom it is likely to have beneficial and / or therapeutic effects, and can also be used to monitor changes in cortisol levels in response to treatment.

The invention discloses compositions, methods and kits for use in treatment of diseases associated with CNS inflammation such as multiple sclerosis. The composition includes therapeutically effective amount of (1-H indazole-4yl-)methanol. Further, a method of inhibiting glial maturation factor beta (GMF-β) phosphorylation activity in cells is disclosed. The method of treating subjects includes administering a therapeutic effective amount of the composition. The administered composition suppresses the activity of the overexpressed GMF-β either by binding or blocking its phosphorylating sites and ameliorating the inflammatory condition. The disclosed compositions, methods and kits may be used in the treatment of diseases like multiple sclerosis, Alzheimer's disease, Parkinson's disease or cancer.