13 results about "Therapeutic radiation" patented technology

Methods and systems of radiosurgical treatment include rotating one or both of a first gantry component and a second gantry component while transmitting a therapeutic treatment beam so as to deliver a therapeutic radiation dose to a target tissue of a patient from one or more arcs extending along a treatment sphere. The first gantry component is rotatable about a first axis and a second gantry component is interfaced with the first gantry component such that rotation of the first gantry component rotates both the first and second gantry components about the first axis. The second gantry component is independently rotatable about a second axis. The method includes coordinating movement of the first and second gantry components along the respective first and second axes so as to allow a trajectory of the therapeutic treatment beam to intersect the target tissue from multiple directions along the treatment sphere.

This invention provides cyclic polypeptide compounds and their uses, specifically disclosing cyclic polypeptide compound A and cyclic polypeptide compound B. Cyclic polypeptide compound A is a compound formed by chelating compound X with a therapeutic radionuclide ion. Cyclic polypeptide compound B is a compound formed by chelating compound X with a diagnostic radionuclide ion. These compounds can be used for the diagnosis and treatment of tumors associated with or mediated by FAP, exhibiting high tumor uptake, long residence times, and broad applicability. JPEG2026513316000414.jpg50104

The invention belongs to the technical field of nuclear medicine, and particularly relates to a PARP inhibitor, a radionuclide marker thereof, a preparation method and application. One purpose of the present invention is to provide a PARP inhibitor, which is a compound represented by a formula I or a salt thereof, and the structure of the compound represented by the formula I is shown in the specification. According to the technical scheme, diagnostic radionuclide (such as 68Ga) and therapeutic radionuclide (such as 177Lu) are compatible through optimal design of the precursor. The advantages fully show that the radionuclide-labeled DOTA-nirapalide has good feasibility and application potential in the aspect of tumor diagnosis and treatment integration.

Methods and systems of radiosurgical treatment include rotating one or both of a first gantry component and a second gantry component while transmitting a therapeutic treatment beam so as to deliver a therapeutic radiation dose to a target tissue of a patient from one or more arcs extending along a treatment sphere. The first gantry component is rotatable about a first axis and a second gantry component is interfaced with the first gantry component such that rotation of the first gantry component rotates both the first and second gantry components about the first axis. The second gantry component is independently rotatable about a second axis. The method includes coordinating movement of the first and second gantry components along the respective first and second axes so as to allow a trajectory of the therapeutic treatment beam to intersect the target tissue from multiple directions along the treatment sphere.

A control circuit accesses patient image content as well as field geometry information regarding a particular radiation treatment platform. The control circuit then generates a predicted three-dimensional dose map for the radiation treatment plan as a function of both the patient image content and the field geometry information.

These various embodiments can serve to facilitate optimizing a radiation treatment plan to administer therapeutic radiation to a particular patient using a particular radiation treatment platform (that may include, for example, a medical linear accelerator) located at a facility having a radiation treatment platform user interface. The radiation treatment platform user interface is coupled to a remote user interface via a secure remote connection that does not permit the remote user interface to operate any radiation delivery capability of the treatment platform nor to execute movement of any of the dynamical components and to then conduct two-way communications (which may be encrypted if desired) between the radiation treatment platform user interface and the remote user interface regarding a radiation treatment plan to administer therapeutic radiation to the particular patient using the particular radiation treatment platform, wherein the two-way communications can include a final approval of an optimized radiation treatment plan.

A control circuit (101) may, before administering therapeutic radiation to a particular patient using a particular radiation treatment apparatus (114) with an optimized radiation treatment plan, access (202) an electronic portal imaging device prediction neural network that was trained with a plurality of training items each comprising information regarding a previous radiation treatment plan and corresponding electronic portal imaging device signal information and then input (203) information regarding the optimized radiation treatment plan to the electronic portal imaging device prediction neural network and output a corresponding predicted electronic portal imaging device signal.

The invention relates to a magnetic resonance imaging radiotherapy system capable of reducing interference on treatment radiation. The system comprises: a magnetic resonance imager (110) comprising a magnet (120) surrounding an aperture (130); a radiation therapy device (140) configured for radiating a therapy beam (160) having a respective radial beam path towards the aperture (130) from a plurality of locations around a longitudinal axis (150) of the aperture; a cold head (170) positioned outside the beam path; and a thermally conductive cooling section (180) in thermal connection with the cold head (170). The cooling section (180) extends azimuthally about a longitudinal axis (150) of the bore. The cooling section (180) is positioned to intersect the beam path, and the width (w) of the cooling section is greater than the maximum width of the treatment beam (180). Preferably, the attenuation of the treatment beam (160) caused by the cooling section (180) is constant between respective beam paths from different positions around the longitudinal axis (150) of the bore.

A method for performing ablative radiotherapy includes registering a first coordinate system of a tracking system for tracking a distal end of an intra-body catheter with a second coordinate system of a beam-directing system, tracking the location of a distal end of the catheter, receiving instructions from a user to ablate target tissue within the body with the beam-directing system and based on the registration and the tracking, aiming the beam-directing system at the target tissue so as to facilitate directing the therapeutic beams of radiation at the target tissue.

The control circuit accesses (201, 203) patient image content and field geometry information about a particular radiation treatment platform. The control circuit then generates (205) a predicted three-dimensional dose map for a radiation treatment plan as a function of both the patient image content and the field geometry information.

A control circuit may, before administering therapeutic radiation to a particular patient using a particular radiation treatment apparatus with an optimized radiation treatment plan, access an electronic portal imaging device prediction neural network that was trained with a plurality of training items each comprising information regarding a previous radiation treatment plan and corresponding electronic portal imaging device signal information and then input information regarding the optimized radiation treatment plan to the electronic portal imaging device prediction neural network and output a corresponding predicted electronic portal imaging device signal.

The present invention relates to methods of minimizing the effects of non-targeted and / or non-therapeutic radiation exposure in an individual. In one aspect, the present invention provides a method of minimizing the effects of non-targeted and / or non-therapeutic radiation exposure in an individual, the method comprising administering a sesquiterpene lactone to the individual, thereby minimizing the effects of non-targeted and / or non-therapeutic radiation exposure in the individual.

Disclosed herein is an imaging system for a radiotherapy device which is configured to provide therapeutic radiation to a patient via a source of therapeutic radiation. The imaging system comprises a source of imaging radiation, a CBCT panel detector, and a CT detector, wherein the source of imaging radiation is configured to be adjustable such that in a first configuration it is configured to emit imaging radiation towards the CT detector and in a second configuration it is configured to emit imaging radiation towards the CBCT detector.