A traditional Chinese medicine composition containing achyranthes bidentata for treating non-alcoholic fatty liver of yin deficiency and excessive heat, and its preparation method and application

A non-alcoholic, yin-deficiency and heat-rich technology, applied in the field of medicine, can solve the problem of synergistic effect of fatty liver transporter specific induction without literature reports and so on.
CN113274453BActive Publication Date: 2022-04-26THE CHINESE TRADITIONAL HERB MEDICINE RES INST HENAN PROV
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
THE CHINESE TRADITIONAL HERB MEDICINE RES INST HENAN PROV
Publication Date
2022-04-26

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Abstract

The invention discloses a traditional Chinese medicine composition containing Achyranthes bidentata for treating non-alcoholic fatty liver of yin deficiency and excessive heat type, and its preparation method and application. The composition includes the following raw materials in parts by weight: Achyranthes bidentata 6~ 18 parts, 12-30 parts of Ophiopogon japonicus, 6-25 parts of Anemarrhena, 15-45 parts of Commelina, 9-27 parts of Dijincao, 3-12 parts of Schisandra, 12-24 parts of Tianjihuang, Daidaihua 10-20 parts, 6-15 parts of lotus leaf, 6-12 parts of kapok, 3-12 parts of Dabupi. The inventors of the present invention have found through research that the composition composed of Ophiopogon japonicus, Anemarrhena, Commelina, Dijincao, Schisandra, Tianjihuang, Daidaihua, lotus leaf, kapok, and Dabupi is effective against yin deficiency and heat. Sheng non-alcoholic fatty liver has a certain therapeutic effect. When used in combination with Achyranthes bidentata, Achyranthes bidentata can increase the distribution concentration of active ingredients of other drugs in liver tissue by up-regulating the expression of Oatp1b2, resulting in a better synergistic effect.
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Description

technical field

[0001] The invention relates to a traditional Chinese medicine composition containing achyranthes bidentata for treating non-alcoholic fatty liver of yin deficiency and heat excess type, a preparation method and application thereof, and belongs to the field of medicine. Background technique

[0002] In recent years, with the improvement of people's living standards, the incidence of non-alcoholic fatty liver has been increasing year by year. The prevalence rate of the general population is about 20% to 33%, and the obesity population is about 57% to 74%. 70% to 80%, the prevalence of diabetes combined with obesity is almost 100%. Non-alcoholic fatty liver (nonalcoholic fatty liverdisease, NAFLD) is a disease without a history of excessive drinking, which is caused by a variety of reasons leading to hepatic lipodystrophy, lipid homeostasis imbalance, resulting in excessive accumulation of lipids in liver cells, and diffuse liver disease. Clinical syndrome of ...

Claims

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