32results about How to "Increase distribution concentration" patented technology

The invention provides a new method for epitaxial growth of an ultraviolet LED. By the adoption of the method for epitaxial growth of the ultraviolet LED, the growth difficulty can be greatly lowered, and the radiant power of the ultraviolet LED is greatly increased. An AlGaN / AlxInyGa1-x-y layer is grown for a plurality of periods, wherein x, y, z and w meet the following requirements for x

The invention discloses a bicyclo-ethanol submicron emulsion and a preparation method thereof. the preparation method comprises the steps of dissolving bicyclo-ethanol and emulsifying agent in an oil phase, adding an assistant for emulsifying agent, a stabilizing agent, other additive and a water phase, adopting a cutting dispersing and high-pressure homogeneous emulsification process to prepare an oil-in-water(O / W) submicron emulsion with the average grain diameter below 500 nm and drug loading dosage between 0.01mg / ml and 5mg / ml. The bicyclo-ethanol submicron emulsion is injected through vein and used for treating medium and serious hepatitis. The prepared submicron emulsion does not contain solubilizer such as Tween-80 or organic solvent, can be mixed with glucose injection, physiological saline or distilled water according to random proportion, and can not easily generate insoluble particulates when stored, used or matched with other components, thereby having high security and good stability. The invention also relates to various preparations of the bicyclo-ethanol submicron emulsion.

The invention discloses an application of organic amine derivatives as the brain-targeting modification group of small-molecule drug and further relates to an organic amine compound having the structure thereof as shown in formula (I), and a preparation method thereof, wherein part B is particularly a central-active drug D, and part A is particularly the targeting modification group of organic amine derivatives. The organic amine compound having the structure as shown in formula (I) and targeting on the brain can significantly increase the aggregation concentration of the drug of the part B on the brain, extend the aggregation time thereof at the brain or improve the effect thereof on the brain.

The invention relates to a micro-powder airflow mill. The micro-powder airflow mill is characterized in that an adjusting gasket and a sorting wheel are arranged on a motor spindle; a motor base is fixedly connected to an upper cover; the upper cover is fixedly connected to a supporting plate of a mill chamber outer shell; the periphery of the motor base is connected with a plurality of air connectors; a mill chamber inner shell is arranged in the mill chamber outer shell; a cavity of the mill chamber inner shell serves as a mill chamber; the bottom of a nozzle fixing disc of the mill chamber inner shell is fixedly connected with a plurality of nozzles; the nozzle fixing disc of the mill chamber inner shell is arranged on a bottom disc; the lower end of the bottom disc is fixedly connected with auxiliary air connectors; the multiple auxiliary air connectors are fixedly connected to an auxiliary air connector fixing seat; a discharging bush is arranged in the center of the nozzle fixing disc and the center of the bottom disc; a clearance is arranged between the end face of the sorting wheel and the end face of the nozzle fixing disc; a feeding mechanism and an air inlet pipe are fixedly connected to the outer circumference face of the mill chamber outer shell; and the lower end of the discharging bush is connected with a finished product discharge opening. The micro-powder airflow mill is reasonable in structure, the material particle size distribution concentration ratio can be effectively increased, product quality is good, and cost is low.

The invention discloses a preparation method for carbon extraction and manganese consercation in medium-manganese high-phosphorus molten steel (Mn is 0.70-0.90wt%, Si is 0.25-0.45wt%, P is 0.120-0.220wt% and S is less than or equal to 0.040wt%) in converter steel making. By adopting the preparation method, processes such as slag retention operation, continuous casting slag application, little slagsmelting, constant pressure gun conversion operation in the smelting process, lowest gun position pressing operation in primary pouring of a converter, and slag wash of whole-process steel discharge,are integrated and created, rapid slag formation in the smelting process is promoted, smelting reaction kinetic and thermodynamic conditions are improved, excellent slagging and phosphorus removal effects are achieved, molten steel and slag splashing in the smelting process is avoided, a MnO allocation concentration is effectively increased, reduction of the MnO at the medium stage of smelting ispromoted, secondary oxidation of Mn in molten steel at the later smelting stage is reduced, furthermore, the content of residual Mn in the molten steel at a final point is remarkably increased (0.25-0.40wt%), the addition amount of a manganese alloy in a deoxidation alloying process is reduced, the steel making alloy consumption and alloying cost can be remarkably reduced, and the market competitiveness of products can be improved.

The invention provides a new method for epitaxial growth of an ultraviolet LED. By the adoption of the method for epitaxial growth of the ultraviolet LED, the growth difficulty can be greatly lowered, and the radiant power of the ultraviolet LED is greatly increased. An AlGaN / AlxInyGa1-x-y layer is grown for a plurality of periods, wherein x, y, z and w meet the following requirements for x<z<1, w<y<1, 0<z+w<1 and 0<x+y<1. Through the component ratio relationship of Al, In and Ga, all components of an AlxInyGa1-x-yN layer can be well matched with lattices of the AlGaN layer, stress is reduced, the crystalline quality of AlGaN and AlxInyGa1-x-y materials is improved, and threading dislocation can also be avoided.

The invention discloses a converter smelting method for improving end molten steel remainder Mn with medium-high-Mn, high-P and low-Si molten iron (C4.20-4.60wt, Mn 0.90wt%-1.15wt%, Si 0.05-0.15wt%, P0.100-0.130wt% and S smaller than or equal to 0.040wt%). Integrated innovation is conducted on processes such as slag retention operation, continuous casting residual slag application, low-alkalinityslagging process, constant-pressure low lance position operation in the smelting process and tapping slag washing in the whole process, smelting reaction dynamics and thermodynamic conditions are optimized, the distribution concentration of MnO in slag in the smelting process is increased, better smelting slagging and dephosphorization effects are obtained under the conditions of little slag andlow-alkalinity slag systems, rephosphorization of molten steel in the later period of smelting and the tapping process is reduced to the greatest extent, the content (0.43wt%-0.55wt%) of end point molten steel residual Mn is significantly increased, the addition amount of Mn alloys in the deoxidation alloying process is reduced, the steelmaking alloy consumption and alloying cost are significantlyreduced, the economic indexes of the smelting technology is improved, and the market competitiveness of products is improved.

The invention relates to a preparation method of special polyvinyl chloride resin for chlorination. The method comprises the following steps: uniformly premixing a quality agent and vinyl chloride monomer in advance, adding deionized water, a dispersing agent I, a dispersing agent II, a PH regulator, a heat stabilizer, a chain transfer agent and an initiator into a polymerization reactor to perform polymerization reaction, ensuring that the quality agent adopts water soluble polyvinyl alcohol with low polymerization degree and low alcoholysis degree, and the dispersing agent I adopts grafted polyvinyl alcohol copolymer resin, and adopting special production technology to premix the quality agent and the vinyl chloride monomer in advance. The special polyvinyl chloride resin for chlorination, prepared through the method, has the advantages that the particle surface films are less or no film exists, the resin particle shapes are regular, the structure is loose, pore distribution is uniform, the degree of concentration of resin particle sizes is high, polymerization reaction is stable during production, and the quality repeatability of all batches of resin is good, and the special polyvinyl chloride resin is particularly applicable to the preparation of chlorinated polyvinyl chloride resin through chlorination.

The invention discloses a traditional Chinese medicine composition containing Achyranthes bidentata for treating non-alcoholic fatty liver of yin deficiency and excessive heat type, and its preparation method and application. The composition includes the following raw materials in parts by weight: Achyranthes bidentata 6~ 18 parts, 12-30 parts of Ophiopogon japonicus, 6-25 parts of Anemarrhena, 15-45 parts of Commelina, 9-27 parts of Dijincao, 3-12 parts of Schisandra, 12-24 parts of Tianjihuang, Daidaihua 10-20 parts, 6-15 parts of lotus leaf, 6-12 parts of kapok, 3-12 parts of Dabupi. The inventors of the present invention have found through research that the composition composed of Ophiopogon japonicus, Anemarrhena, Commelina, Dijincao, Schisandra, Tianjihuang, Daidaihua, lotus leaf, kapok, and Dabupi is effective against yin deficiency and heat. Sheng non-alcoholic fatty liver has a certain therapeutic effect. When used in combination with Achyranthes bidentata, Achyranthes bidentata can increase the distribution concentration of active ingredients of other drugs in liver tissue by up-regulating the expression of Oatp1b2, resulting in a better synergistic effect.

The invention discloses a preparation method of a preparation method of C-extracted and Mn-kept molten steel (Mn 1.20wt%-1.50wt%, Si smaller than or equal to 0.20wt%, 0.130wt%-0.180wt% of P) with high-Mn, low-Si and high-P molten iron for converter smelting. Integrated innovation is performed on processes such as slag remaining operation, little slag smelting, constant-pressure lance change operation in the smelting process, converter-lowest lance position press operation, slag washing in the tapping process and bottom argon blowing in the whole process, the smelting reaction kinetics and thermodynamic conditions are optimized, good slagging dephosphorization and desulfurization effects are obtained, molten steel and slag splashing in the smelting process are avoided, the distribution concentration of MnO in slag is effectively increased, reduction of MnO in slag in the middle period of smelting, reoxidation of Mn in molten steel in the later period of smelting is reduced, the residualMn content (0.40wt%-0.60wt%) in end molten steel is significantly increased, the addition amount of a manganese alloy in the deoxidation alloying process is substantially reduced, the steelmaking alloy consumption and alloying cost is reduced significantly, and the market competitiveness of steel products is improved.

The invention provides an application of pH (potential of hydrogen) sensitive polyethylene glycol derivative and small molecule drug conjugate in a formula (I) and polymer micelle thereof as an inflammatory targeting delivery system and a preparation method of the pH sensitive polyethylene glycol derivative and small molecule drug conjugate. A portion B includes a small molecule drug D with inflammatory disease treating activity, and a portion A includes a polyethylene glycol derivative carrier system. The pH sensitive polyethylene glycol derivative and small molecule drug conjugate polymer micelle has good inflammatory targeting property, the concentration of the drug in the portion B at a low-pH inflammatory site can be remarkably increased, or staying time of the drug at the low-pH inflammatory site can be prolonged, or the anti-inflammatory effect of the drug can be enhanced.

The invention discloses a bicyclo-ethanol submicron emulsion and a preparation method thereof. the preparation method comprises the steps of dissolving bicyclo-ethanol and emulsifying agent in an oil phase, adding an assistant for emulsifying agent, a stabilizing agent, other additive and a water phase, adopting a cutting dispersing and high-pressure homogeneous emulsification process to prepare an oil-in-water(O / W) submicron emulsion with the average grain diameter below 500 nm and drug loading dosage between 0.01mg / ml and 5mg / ml. The bicyclo-ethanol submicron emulsion is injected through vein and used for treating medium and serious hepatitis. The prepared submicron emulsion does not contain solubilizer such as Tween-80 or organic solvent, can be mixed with glucose injection, physiological saline or distilled water according to random proportion, and can not easily generate insoluble particulates when stored, used or matched with other components, thereby having high security and good stability. The invention also relates to various preparations of the bicyclo-ethanol submicron emulsion.

The invention relates to a micro-powder airflow mill. The micro-powder airflow mill is characterized in that an adjusting gasket and a sorting wheel are arranged on a motor spindle; a motor base is fixedly connected to an upper cover; the upper cover is fixedly connected to a supporting plate of a mill chamber outer shell; the periphery of the motor base is connected with a plurality of air connectors; a mill chamber inner shell is arranged in the mill chamber outer shell; a cavity of the mill chamber inner shell serves as a mill chamber; the bottom of a nozzle fixing disc of the mill chamber inner shell is fixedly connected with a plurality of nozzles; the nozzle fixing disc of the mill chamber inner shell is arranged on a bottom disc; the lower end of the bottom disc is fixedly connected with auxiliary air connectors; the multiple auxiliary air connectors are fixedly connected to an auxiliary air connector fixing seat; a discharging bush is arranged in the center of the nozzle fixing disc and the center of the bottom disc; a clearance is arranged between the end face of the sorting wheel and the end face of the nozzle fixing disc; a feeding mechanism and an air inlet pipe are fixedly connected to the outer circumference face of the mill chamber outer shell; and the lower end of the discharging bush is connected with a finished product discharge opening. The micro-powder airflow mill is reasonable in structure, the material particle size distribution concentration ratio can be effectively increased, product quality is good, and cost is low.

The invention discloses a method for compressing and decompressing data of this frame with high compression rate and high reductibility, including a compression method and a decompression method; The coefficient interception is performed on the WHT transformed data, the stepwise quantization is performed on the retained data after interception, the bit stream recombination is performed on the quantization result, and the byte stream data after the bit stream recombination is obtained, and then the byte stream data is compressed by compression coding. , get the final compressed data and output it. The decompression method is a reverse operation to obtain decompressed data. The method for compressing and decompressing data of this frame of the present invention has the characteristics of high compression rate and high reduction rate. By simplifying the data processing unit, the compression rate and reducibility are improved, thereby reducing the occupied capacity in the process of storage and transmission, and at the same time improving the transmission rate. speed, shorten the transmission time, and ensure the real-time and stability of the data.

The invention relates to a method for preparing anti-hardening cotton wool, which belongs to the technical field of pesticide synthesis. In order to solve the existing problem of short storage time and easy agglomeration, a method for preparing cotton wool that is resistant to hardening is provided. The method includes adding a permanganate aqueous solution to the carbon disulfide solution for pretreatment, layering, and collecting the pretreated Carbon disulfide solution; react the pretreated carbon disulfide solution with concentrated methylamine aqueous solution to obtain an aqueous solution containing N-methyldithiocarbamic acid; in the presence of phosphate, amphoteric surfactant and EDTA, react with formaldehyde to obtain The amount of phosphate added is 1.0%-1.5% of the mass of formaldehyde, and the mass ratio of phosphate: amphoteric surfactant: EDTA is 1:0.5-0.6:0.01-0.02. The invention can increase the uniformity and distribution concentration of the particles and increase the compaction resistance of the cotton wool particles, so as to have the effect of high fluidity.

The invention discloses a preparation method for carbon extraction and manganese consercation in medium-manganese high-phosphorus molten steel (Mn is 0.70-0.90wt%, Si is 0.25-0.45wt%, P is 0.120-0.220wt% and S is less than or equal to 0.040wt%) in converter steel making. By adopting the preparation method, processes such as slag retention operation, continuous casting slag application, little slagsmelting, constant pressure gun conversion operation in the smelting process, lowest gun position pressing operation in primary pouring of a converter, and slag wash of whole-process steel discharge,are integrated and created, rapid slag formation in the smelting process is promoted, smelting reaction kinetic and thermodynamic conditions are improved, excellent slagging and phosphorus removal effects are achieved, molten steel and slag splashing in the smelting process is avoided, a MnO allocation concentration is effectively increased, reduction of the MnO at the medium stage of smelting ispromoted, secondary oxidation of Mn in molten steel at the later smelting stage is reduced, furthermore, the content of residual Mn in the molten steel at a final point is remarkably increased (0.25-0.40wt%), the addition amount of a manganese alloy in a deoxidation alloying process is reduced, the steel making alloy consumption and alloying cost can be remarkably reduced, and the market competitiveness of products can be improved.

The invention discloses a preparation method for carbon extraction and manganese consercation in medium-manganese high-sulfur high-phosphorus molten steel (Mn is 1.20-1.90wt%, Si is 0.070-0.090wt%, Pis 0.120-0.200wt% and S is 0.20-0.40wt%) in converter steel making. By adopting the preparation method, processes such as slag retention operation, addition of a small amount of manganese spheres at the early stage of smelting, little slag smelting, constant pressure gun conversion operation in the smelting process, lowest gun position pressing operation in primary pouring of a converter, and slagwash of whole-process steel discharge, are integrated and created, smelting reaction kinetic and thermodynamic conditions are improved, excellent slugging and phosphorus removal effects are achieved,molten steel and slag splashing in the smelting process is avoided, a MnO allocation concentration is effectively increased, reduction of the MnO at the medium stage of smelting is promoted, secondary oxidation of Mn in molten steel at the later smelting stage is reduced, furthermore, the content of residual Mn in the molten steel at a final point is remarkably increased (0.40-0.60wt%), the addition amount of a manganese alloy in a deoxidation alloying process is reduced, the steel making alloy consumption and alloying cost can be remarkably reduced, improvement of economic indexes of a smelting technique is promoted, and the market competitiveness of products can be improved.

The invention discloses a converter smelting method for increasing residual manganese of end point liquid steel by high and medium-manganese hot metal (C, 0.75 to 1.10wt% of Mn, 0.25 to 0.45wt% of Si,0.090 to 0.120wt% of P, and less than or equal to 0.045wt% of S). The converter smelting method has the advantages that the technologies of remaining slag operation, low-alkalinity BaCO3 system slagmanufacturing, fewer-slag smelting, constant-pressure and low-gun level gun change in a smelting process, slag washing in a whole tapping process and the like are adopted, integrated and innovated, soas to optimize the reaction dynamics and thermodynamics conditions of smelting, avoid the splashing of liquid steel and furnace slag in the smelting process, and increase the distribution concentration of slag (MnO) in the smelting process; the good smelting slugging and dephosphorization effect is obtained under the technology conditions of low-alkalinity slag system and fewer slag, and the phosphor return degree of the liquid steel in the later smelting process and the tapping process is effectively reduced; the content of residual Mn in the end point liquid steel is obviously increased to0.38 to 0.50wt%, the adding amount of manganese alloy in the deoxidizing alloy process is greatly reduced, the consumption of steel smelting alloy and the alloying cost are obviously reduced, the improvement of technical and economic indexes in smelting are promoted, and the market competitiveness of a product is improved.

The invention discloses a jasminoidin or gardenia total iridoid glycoside liposome preparation which comprises liposome formed by phospholipid and cholesterol, and asminoidin or gardenia total iridoid glycoside wrapped and loaded in the liposome, wherein the weight ratio of phospholipid to cholesterol is (3:1)-(7:1), preferably 5:1; the weight ratio of asminoidin or gardenia total iridoid glycoside to phospholipid is (1:2)-(1:8), preferably 1:4; and the phospholipid is selected from lecithin, soya lecithin, yolk phospholipid or phosphatidylcholine, preferably soya lecithin or yolk phospholipid. The preparation provided by the invention has the advantages that the contact time of the asminoidin or gardenia total iridoid glycoside and mucosa is prolonged. The liposome preparation can be prepared into a spraying agent after being loaded into a nasal suction apparatus, and is applied in a nasal delivery mode, so that the distribution of the asminoidin or gardenia total iridoid glycoside in brain tissues is effectively improved. The invention also discloses the application of the liposome preparation in preparation of medicaments for treating hypoxic ischemic brain damage diseases.

The invention discloses a preparation method for carbon extraction and manganese consercation in medium-manganese low-silicon high-phosphorus molten steel (Mn is 0.70-0.90wt%, Si is 0.06-0.15wt%, P is0.130-0.220wt% and S is less than or equal to 0.045wt%) in converter steel making. By adopting the preparation method, processes such as slag retention operation, continuous casting slag application,little slag smelting, constant pressure gun conversion operation in the smelting process, lowest gun position pressing operation in primary pouring of a converter, and slag wash of whole-process steel discharge, are integrated and created, low-silicon molten steel smelting slagging elements and heat sources are increased, rapid slag formation in the smelting process is promoted, smelting reactionkinetic and thermodynamic conditions are improved, excellent slugging and phosphorus removal effects are achieved, molten steel and slag splashing in the smelting process is avoided, a MnO allocationconcentration is effectively increased, reduction of the MnO at the medium stage of smelting is promoted, secondary oxidation of Mn in molten steel at the later smelting stage is reduced, furthermore, the content of residual Mn in the molten steel at a final point is remarkably increased (0.25-0.38wt%), the addition amount of a manganese alloy in a deoxidation alloying process is reduced, the steel making alloy consumption and alloying cost can be remarkably reduced, and the market competitiveness of products can be improved.

The invention discloses a preparation method for carbon extracting and manganese retaining of high-manganese high-silicon and high-phosphorus molten iron through converter smelting, wherein the high-manganese high-silicon and high-phosphorus molten iron comprises, by weight, 1.10-1.50% of Mn, 0.70-1.00% of Si, 0.120-0.170% of P, and 0.035% or the less of S. According to the preparation method, theprocesses such as slag retaining operation, double-slag slag making process, less slag smelting, constant-pressure gun changing operation in the smelting process, converter direct lowest-gun-positiongun pressing operation, slag washing in the steel discharging process, and whole-process bottom argon blowing are adopted and integrally innovated, thus kinetics and thermodynamic conditions of a smelting reaction are optimized, the good smelting slagging dephosphorization and desulfurization effects are obtained, splashing of molten steel and slag in the smelting process is avoided, the distribution concentration in the slag (MnO) is effectively increased, reduction in the slag (MnO) at the smelting medium stage is promoted, re-oxidation of Mn in the molten steel at the smelting later stageis lowered, the end point molten steel residual Mn content (0.35-0.55wt%) is significantly increased, the adding amount of a manganese-series alloy in the deoxidizing alloying process is reduced, steelmaking alloy consumption and the alloying cost are significantly lowered, and the product market competitiveness is improved.

The invention discloses a converter smelting method for improving end-point molten steel residual manganese in high-manganese and high-silica molten iron (4.40 to 4.80 weight percent of C, 1.10 to 1.30 weight percent of Mn, 0.75 to 1.00 weight percent of Si, 0.085 to 0.105 weight percent of P and 0.015 to 0.035 weight percent of S). According to the method, by adopting technologies such as low alkalinity slag making technology, constant pressure gun change operation at gun position during smelting process, converter inverting gun pressing operation at minimum gun position, steel tapping whole-process wash heat process and carrying out integrated innovation, kinetic and thermodynamic conditions of smelting reaction are optimized, the distribution concentration of the slag (MnO) in the smelting process is improved and better smelting dephosphorizing effect is obtained under the conditions of less slag and a low basicity slag system; moreover, molten steel rephosphorization at the late smelting period and in the steel tapping process is reduced to the maximum extent, so that the residual Mn content (0.48 to 0.65 weight percent) of end-point molten steel is significantly increased, theadding amount of a manganese alloy during the deoxygenation alloying process is significantly reduced, the consumption of steelmaking alloys and the alloying cost are reduced, the improvement of smelting technical and economic indicators is promoted and further the market competitiveness of a product is improved.