External taurine medicine for treating myopia as well as preparation method and application of external taurine medicine

A technology of taurine and external medicine, applied in the field of medicine, can solve the problems of reducing drug efficacy, not appearing in application, affecting drug absorption and utilization, etc., to achieve the effects of reducing edema, inhibiting the occurrence and development, and improving nerve conduction and visual function

Pending Publication Date: 2022-03-08
裴丽林
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Excessive tears will dilute the drug concentration and overflow the eyes or enter the nasal cavity and oral cavity, thereby affecting the absorption and utilization of the drug and reducing the drug effect
And there is no application of it in the treatment of myopia and myopic amblyopia

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0050] A taurine eye drop for treating myopia, the taurine eye drop is prepared from the following raw materials: 50.51 g of taurine, 12.09 g of boric acid, 0.57 g of anhydrous borax, 0.30 g of ethylparaben, 95 Add 1.50ml of % ethanol and distilled water to 1000ml. The milliosmolality of the taurine eye drops is 628.27 mosmol / kg; the concentration of taurine in the taurine eye drops is 0.051 g / ml. The pH value of the obtained taurine eye drops is 6.77.

Embodiment 2

[0052] A taurine eye drop for treating myopia, the taurine eye drop is prepared from the following raw materials: 50.51 g of taurine, 11.22 g of boric acid, 1.91 g of anhydrous borax, 0.25 g of ethylparaben, 95 Add 1.25ml of % ethanol and distilled water to 1000ml. The milliosmolality of the taurine eye drops is 618.48 mosmol / kg; the concentration of taurine in the taurine eye drops is 0.051 g / ml. The pH value of the obtained taurine eye drops is 7.36.

Embodiment 3

[0054] A taurine external medicine for treating myopia, including taurine eye drops and taurine eye patches;

[0055] Taurine eye drops are the taurine eye drops described in embodiment 1 or embodiment 2;

[0056] The taurine eye patch includes taurine eye patch and eye patch spunlace non-woven fabric. The taurine eye patch is prepared from the following raw materials: 50.51g of taurine, 12.09g of boric acid, anhydrous borax Add 0.57g, 0.30g of ethylparaben, 1.50ml of 95% ethanol, and distilled water to 1500ml. The milliosmolality of the taurine eye patch is 418.85 mosmol / kg; the concentration of taurine in the taurine eye patch is 0.034g / ml. The pH value of the obtained taurine eye patch is 6.90. The hydroentangled non-woven fabric of the eye patch is oval, with a diameter of 8.1 cm in the transverse major axis and a diameter of 5.6 cm in the longitudinal major axis.

[0057] The preparation method of this taurine eye patch, comprises the following steps:

[0058] S1, pre...

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Abstract

The invention discloses a taurine external medicine for treating myopia as well as a preparation method and application thereof. The external use medicine comprises taurine eye drops and taurine eye patches. The taurine eye pad comprises taurine eye pad liquid and spunlace non-woven fabric for the eye pad. Each of the taurine eye drops and the taurine eye patch liquid comprises taurine, boric acid, anhydrous borax, ethylparaben and ethanol. The invention further discloses a medicine for treating myopia. The medicine comprises an external medicine and an internal medicine. When the taurine external use medicine is applied to the outside of eyes, the absorption of taurine in eye tissues can be obviously promoted through a skin hydration method, the distribution concentration of taurine in the eye tissues is greatly improved, and eye diseases caused by taurine metabolic disorder are effectively treated. And injection is not needed, and the eye patch can be directly applied to the eyes conveniently and quickly and is convenient to carry.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to a taurine external medicine for treating myopia, a preparation method and application thereof. Background technique [0002] Taurine is a sulfur-containing amino acid with simple structure in animals, which is widely distributed in various tissues and organs in the body. Taurine is the most abundant amino acid in the retina, vitreous, lens, cornea, iris and ciliary body. It can promote the brain tissue and intellectual development of infants and young children, and can improve nerve conduction and visual function. If the infant lacks taurine in the body, there will be mental retardation and retinal dysfunction; for patients who have been given intravenous nutrition infusion for a long time, if there is no taurine in the nutrient solution, the electroretinogram of the patient will change, and only Adding large doses of taurine can correct this change. Taurine also ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/185A61K33/22A61K33/30A61K9/70A61K9/08A61K9/24A61P27/10A61P27/12A61P27/02A61P31/12A61P31/22A61P7/10A61K33/24A61K33/14A61K33/10A61K33/06A61K33/04A61K31/593A61K31/525A61K31/51A61K31/455A61K31/4415A61K31/375A61K31/355A61K31/198A61K31/07A61K31/047A61K31/015A61K31/7076
CPCA61K31/185A61K33/22A61K33/30A61K33/24A61K33/14A61K33/10A61K33/06A61K33/04A61K31/593A61K31/525A61K31/51A61K31/455A61K31/4415A61K31/375A61K31/355A61K31/198A61K31/07A61K31/047A61K31/015A61K31/7076A61K9/7023A61K9/0048A61K9/08A61K9/2095A61K9/2059A61K9/209A61P27/10A61P27/12A61P27/02A61P31/12A61P31/22A61P7/10A61K2300/00
Inventor 裴丽林罗茜茜
Owner 裴丽林
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