The invention discloses a time-of-flight
mass analysis device, which comprises an
ionization acceleration region for generating ions, screening the ions according to the initial energy and initial position of the ions and accelerating the ions to move towards a field-free region; the field-free region is used for providing free
motion space with enough distance for ions; the reflection area is located at the
tail end of the field-free area and used for reflecting ions to the
signal detection area; and the
signal detection area is used for detecting
ion types. The
ionization acceleration area of the device adopts a
voltage driving mode of repulsion pulses and introduction of the pulses to reduce the initial space dispersion and initial
energy dispersion of ions, meanwhile, the
ionization probability of molecules is increased, and the resolution and sensitivity of time-of-flight
mass analysis can be improved.