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This invention relates to a multidimensional feedback-based interactive nebulizer inhalation system for children, comprising: a flow regulation component having a dosing state and an blocking state; a detection module for acquiring vital sign monitoring data; a feedback execution module including an interactive prompting unit and a drive unit; and a control module communicatively connected to the detection module and the feedback execution module. The control module is configured to execute the following processing flow: receiving vital sign monitoring data to assess airway safety risks and nebulization operation compliance respectively; when there is an abnormal airway safety risk, generating a collaborative intervention command: the command drive unit switches the flow regulation component to the blocking state and simultaneously controls the interactive prompting unit to output soothing interactive information; when there is no abnormal airway safety risk, controlling the interactive prompting unit to output interactive information for action correction or positive guidance based on the compliance assessment results.