Fingerprint spectrum detection method for Ganshuang granules

A fingerprint and detection method technology, applied in the field of spectrum detection, can solve the problems that it is difficult to fully reflect the comprehensive information of drugs and complex components, and achieve the effects of high reliability, good reproducibility and high stability

Pending Publication Date: 2021-10-22
BAODING BUCHANG TIANHAO PHARMA +1
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

However, because Ganshuang Granules have many medicinal flavors and complex components, the analysis of individual components is somewhat one-sided. To control the quality of Gan

Method used

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  • Fingerprint spectrum detection method for Ganshuang granules
  • Fingerprint spectrum detection method for Ganshuang granules
  • Fingerprint spectrum detection method for Ganshuang granules

Examples

Experimental program
Comparison scheme
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Example Embodiment

[0061] Example

[0062] The liver-cool particle fingerprint spectrum detection method provided in this embodiment includes the following steps:

[0063] 1) EtOAc EtOAc EtOAc EtOAc EtOAc EtOAc EtOAc.

[0064] The specific process is precisely referred to as a liver particle powder 0.3 g, and placed in a conical bottle, adding a mass concentration of 70% methanol aqueous solution 50ml, ultrasonic treatment for 30 min, cooling, using a mass concentration of 70% methanol aqueous solution The loss of mass, set, shaken, centrifuged at 1200 rpm for 10 min, taking the supernatant, a 0.3 μm microporous filter, and the filtrate is a test solution.

[0065] In this embodiment, the ultrasonic power is 600 W, the ultrasonic frequency is 35 kHz, and the time is 20 min.

[0066] In this embodiment, the hepatin particles are 200816 batch for samples.

[0067] 2) High-performance liquid chromatography detection of the test solution in ultra-efficient liquid chromatography (see chromatographic data...

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Abstract

The invention belongs to the technical field of spectrum detection, and relates to a fingerprint spectrum detection method for Ganshuang granules, which comprises: 1) carrying out ultrasonic extraction on Ganshuang granules by using methanol to obtain a to-be-detected test solution; (2) carrying out high performance liquid chromatography detection on the test solution by adopting ultra-high performance liquid chromatography, and recording chromatographic data within 40 minutes; and generating the fingerprint spectrum of the Ganshuang granules from the chromatographic data according to the 'Traditional Chinese Medicine Chromatographic Fingerprint Similarity Evaluation System A'. The detection method provided by the invention has the characteristics of high accuracy, high stability and good repeatability, can comprehensively reflect the quality of the Ganshuang granules, and ensures the product quality.

Description

technical field [0001] The invention belongs to the technical field of spectrum detection and relates to a fingerprint spectrum detection method of Ganshuang granules. Background technique [0002] The fingerprint of traditional Chinese medicine refers to the chromatogram or spectrum of a certain type or several types of components that are common in certain Chinese medicinal materials or Chinese patent medicines. The characteristics of fingerprints of traditional Chinese medicine include integrity, characteristic and quantification, highlighting the complete appearance of traditional Chinese medicine, and its role in the study of active ingredients of traditional Chinese medicine, quality control and identification of traditional Chinese medicine is becoming more and more prominent. [0003] Ganshuang Granules (Guoyao Zhunzi Z20027671) is an exclusive traditional Chinese medicine variety produced by Baoding Buchang Tianhao Pharmaceutical Co., Ltd. It has a unique curative e...

Claims

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Application Information

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IPC IPC(8): G01N30/86G01N30/02G01N30/34G01N30/74G01N30/06G01N30/14
CPCG01N30/8686G01N30/02G01N30/34G01N30/74G01N30/06G01N30/14G01N30/8634G01N30/8679G01N2030/146
Inventor 刘峰韩东彭修娟李林林许刚陈衍斌刘金华程茜菲李波谢伟
Owner BAODING BUCHANG TIANHAO PHARMA
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