Inhalation type atomized liquid for regulating and controlling virus gene expression and preparation method of inhalation type atomized liquid

A technology of virus gene and atomized liquid, which is applied in antiviral agents, medical preparations containing active ingredients, pharmaceutical formulas, etc., can solve the problems of low miRNA2911 content, inability to reach effective concentration, and ineffective effect, etc., to promote cell Regeneration, good application prospect, quick effect

Inactive Publication Date: 2022-01-28
深圳本草雾华科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The present invention aims at the problem that the content of miRNA2911 in the existing drugs for regulating viral gene expression is very low, the effective concentration cannot be reached, the absorption rate is low, and the effect is not obvious. The present invention provides an inhalation atomization liquid for regulating viral gene expression and its preparation method

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] The preparation of the inhalation aerosol for regulating viral gene expression comprises the following steps:

[0031] S1: Weigh 50kg of green tea, 50kg of honeysuckle, 50kg of white orchid and 50kg of bergamot;

[0032] S2: Prepare green tea Zhenlu

[0033] At 195°C, use the preparation method disclosed in Example 1 of Authorized Publication No. CN104187474B to extract the volatile components, water-soluble components and / or fat-soluble components of green tea in step S1;

[0034] The above-mentioned ingredients are evenly polymerized to obtain green tea Zhenlu;

[0035] S3: Preparation of Honeysuckle Zhenlu

[0036] At 190°C, use the preparation method disclosed in Example 1 of Authorized Publication No. CN104187474B to extract the volatile components, water-soluble components and / or fat-soluble components of honeysuckle in step S1;

[0037] The above-mentioned ingredients are evenly polymerized to obtain Honeysuckle Zhenlu;

[0038] S4: Prepare white orchid dew ...

Embodiment 2

[0047] The preparation of the inhalation aerosol for regulating viral gene expression comprises the following steps:

[0048] S1: Weigh 100kg of green tea, 100kg of honeysuckle, 50kg of white orchid and 50kg of bergamot;

[0049] S2: Prepare green tea Zhenlu

[0050] At 198°C, use the preparation method disclosed in Example 1 of the authorized publication number CN104187474B to extract the volatile components, water-soluble components and / or fat-soluble components of green tea in step S1;

[0051] The above-mentioned ingredients are evenly polymerized to obtain green tea Zhenlu;

[0052] S3: Preparation of Honeysuckle Zhenlu

[0053] At 195°C, use the preparation method disclosed in Example 1 of Authorized Publication No. CN104187474B to extract the volatile components, water-soluble components and / or fat-soluble components of honeysuckle in step S1;

[0054] The above-mentioned ingredients are evenly polymerized to obtain Honeysuckle Zhenlu;

[0055] S4: Prepare white orc...

Embodiment 3

[0064] The preparation of the inhalation aerosol for regulating viral gene expression comprises the following steps:

[0065] S1: Weigh 80kg of green tea, 100kg of honeysuckle, 80kg of white orchid and 40kg of bergamot;

[0066] S2: Prepare green tea Zhenlu

[0067]At 205°C, use the preparation method disclosed in Example 1 of Authorized Publication No. CN104187474B to extract the volatile components, water-soluble components and / or fat-soluble components of green tea in step S1;

[0068] The above-mentioned ingredients are evenly polymerized to obtain green tea Zhenlu;

[0069] S3: Preparation of Honeysuckle Zhenlu

[0070] At 200°C, use the preparation method disclosed in Example 1 of Authorized Publication No. CN104187474B to extract the volatile components, water-soluble components and / or fat-soluble components of honeysuckle in step S1;

[0071] The above-mentioned ingredients are evenly polymerized to obtain Honeysuckle Zhenlu;

[0072] S4: Prepare white orchid dew ...

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PUM

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Abstract

The invention discloses inhalation type atomized liquid for regulating and controlling viral gene expression and a preparation method of the inhalation type atomized liquid. The inhalation type atomized liquid for regulating and controlling viral gene expression is mainly prepared from the following raw materials in parts by weight: 5-20 parts of green tea, 5-15 parts of lonicerae flos, 5-15 parts of michelia alba and 5-15 parts of bergamot. The inhalation type atomized liquid has an inhibition effect on gene expression of viruses, so that virus infection diseases can be treated.

Description

technical field [0001] The invention belongs to the technical field of regulating viral gene expression, and in particular relates to an inhalation atomized liquid for regulating viral gene expression and a preparation method thereof. Background technique [0002] miRNA is a kind of endogenous small ribonucleic acid with a length of about 20-24 nucleotides, which has many important regulatory functions in cells. miRNAs are highly conserved among different species. In recent years, studies have suggested that miRNAs can regulate gene expression across species. miRNA2911 has binding sites on the genomes of 94% of viruses; domestic and foreign studies have also proved that miRNA2911 has a broad-spectrum inhibitory effect on varicella-zoster virus, enterovirus, Ebola virus, The ability of Zika virus, African swine fever virus, Middle East respiratory fever virus and porcine rotavirus and other viruses. [0003] The existing drugs for regulating viral gene expression contain ve...

Claims

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Application Information

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IPC IPC(8): A61K9/72A61K9/12A61K36/82A61P31/12A61P31/16
CPCA61K9/12A61K9/0073A61K36/82A61K36/355A61K36/57A61K36/752A61P31/12A61P31/16A61K2300/00
Inventor 金湘范
Owner 深圳本草雾华科技有限公司
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