Application of myristic acid in preparation of brain aging resisting medicine
A technology of myristic acid, brain aging, applied in the direction of drug combination, anhydride/acid/halide active ingredients, nervous system diseases, etc., to achieve the effect of improving exploration ability, improving spatial memory, and increasing percentage
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[0024] In this example, natural aging mice were used to conduct experiments to study the therapeutic effect of MA on brain aging.
[0025] 1. Experimental materials and methods
[0026] 1. Mice
[0027] 22-month-old C57BL / 6 male mice were purchased from the Experimental Animal Center of Guangzhou University of Traditional Chinese Medicine (GZUCM) (animal production certificate #(Yue) 20180034). All animal experiments were approved by the Ethics Committee of the First Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine (approval number TCMF1-2021026). The 22-month-old mice were randomly divided into two groups: 22-month-old mice (22M, intraperitoneal injection of the same amount of solvent) and MA (MA+22M, 2 mg / kg·d MA intraperitoneal injection). The drug is administered by intraperitoneal injection for 2 months. Following behavioral assessments (open field and water maze experiments), mouse brain samples were taken for subsequent experimental assessm...
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