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Calcium, zinc and ferrum composite oral liquor and its preparing process

A technology of zinc-iron oral liquid and iron oral liquid, which is applied in the field of calcium-zinc-iron oral liquid and its preparation, can solve problems such as poor absorption, failure to achieve therapeutic effect, untreated zinc and iron deficiency, etc., and achieve fast absorption, Effects of increased symptoms and therapeutic range, increased iron absorption

Inactive Publication Date: 2007-02-21
岳阳新华达制药有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the intestinal tract of a normal person can only absorb 30% of the intake. Therefore, although many patients take calcium supplements, they cannot achieve a good therapeutic effect due to poor absorption; In patients with iron deficiency, although the calcium deficiency has improved, the zinc and iron deficiencies are still untreated

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0015] Embodiment 1: select following medicinal composition and the weight ratio with water for use:

[0016] Calcium Gluconate 4000g

[0017] Ferrous Gluconate 1000g

[0018] Zinc Gluconate 300g

[0019] Vitamin B 2 30 grams

[0020] Add 100 kg of deionized water into the liquid preparation tank, heat to 100°C, add calcium gluconate first according to the preparation components, and after heating for 2 hours, then add ferrous gluconate, zinc gluconate, and vitamin B in sequence 2 , continue to stir, heat until completely dissolved, and mix well; add deionized water to make the weight ratio of total water to drug 100:5.33, stir for 1.5 hours, cool to 30°C, enter secondary filtration, and obtain oral liquid 105.33 kg, filled into bottles, each 10ml, is the oral liquid product of the present invention.

Embodiment 2

[0021] Embodiment 2: select following medicinal composition and the weight ratio with water for use:

[0022] Calcium Gluconate 5000g

[0023] Ferrous Gluconate 800g

[0024] Zinc Gluconate 500g

[0025] Vitamin B 2 30 grams

[0026] Add 100 kg of deionized water into the liquid preparation tank, heat to 100°C, add calcium gluconate first according to the preparation components, and after heating for 2 hours, then add ferrous gluconate, zinc gluconate, and vitamin B in sequence 2 , continue to stir, heat until completely dissolved, and mix well; add deionized water to make the weight ratio of total water to drug 100:6.33, stir for 1.5 hours, cool to 30°C, and enter the secondary filter to obtain oral liquid 106.33 kg, filled into bottles, each 10ml, is the oral liquid product of the present invention.

Embodiment 3

[0027] Embodiment 3: select following medicinal composition and the weight ratio with water for use:

[0028] Calcium Gluconate 3000g

[0029] Ferrous Sulfate 1200g

[0030] Zinc Gluconate 400g

[0031] Vitamin B 2 40 grams

[0032] Add 100kg of deionized water into the liquid preparation tank, heat to 100°C, add calcium gluconate first according to the preparation components, after heating for 2 hours, then add ferrous sulfate, zinc gluconate, and vitamin B in sequence 2 , continue to stir, heat until completely dissolved, and mix well; add deionized water to make the weight ratio of total water to drug 100:4.64, stir for 1.5 hours, cool to 30°C, enter secondary filtration, and obtain oral liquid 104.64 kg, filled into bottles, each 10ml, is the oral liquid product of the present invention.

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PUM

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Abstract

The invention provides a calcium, zinc and ferrum composite oral liquor and its preparing process, wherein the oral liquid comprises the constituents of (by weight percent) soluble calcium agent 2-8 parts, soluble ferrum agent 0.5-3 parts, soluble zinc agent 0.1-0.6 part, vitamin B2 0.01-0.06 part, water by the weight ratio of 100 : 2-12. The process for preparation comprises the steps of heating, stirring, mixing, cooling down, secondary filtering, loading and sterilizing.

Description

1. Technical field: [0001] The invention relates to a calcium-zinc-iron oral liquid and a preparation method thereof. 2. Background technology: [0002] Calcium, zinc, and iron deficiency is a medical problem that people generally face at present, especially calcium deficiency, which has attracted more and more people's attention. According to the data, about 70% of the infants in the world have different degrees of calcium deficiency. Therefore, the proportion of infants suffering from rickets in our country is as high as 25%. In addition, there are quite a few infants suffering from zinc and iron deficiency. Defect disease and thus caused a series of syndromes. 50% of pregnant women need to supplement calcium. Calcium deficiency in the fetal period has attracted more and more attention. It has become a routine health care regulation for pregnant women to supplement calcium. Most people also need to supplement zinc and iron at the same time. As we all know, osteoporosis i...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/525A61P3/02A61K31/191
Inventor 郭凌云黄如平随裕敏罗春林
Owner 岳阳新华达制药有限公司
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