Process for extracting ursolic acid from fructus ligustri lucidi leaf

Abstract

The method for extracting ursolic acid from ligustrum leaf includes the following steps: making pulverized ligustrum leaf undergo the process of counter-current extraction with reflux to obtain liquid extract, recovering ethyl alcohol, fully washing said liquid extract with water, drying to obtain dried extract, dissolving said dried extract in ethyl alcohol and decoloring, recovering ethyl alcohol from the decoloring liquor and adding water to separate out lots of precipitate, regulating pH value to 2-2.5, separating and collecting precipitate, washing with water to neutrality and vacuum drying to obtain crude extract whose main component is ursolic acid. said invention used ethyl alcohol can be recovered and reused, and the waste residue produced after extraction can be used as fertilizer.

Description

1. Technical field

[0001] The invention relates to a method for extracting ursolic acid from privet leaves. 2. Background technology

[0002] Ligustrum is a plant of the genus Ligustrum of the Oleaceae family. The scientific name is Ligustrum Lucidum Ait. It is a large evergreen shrub or small tree in all seasons. There are about 50 species in the world, and there are 38 species in my country. They are widely distributed in East China, South China, Southwest China and Central China is rich in plant resources and widely distributed.

[0003] With the deepening of pharmacological research, it is found that privet plants have various physiological activities, but the research on the chemical constituents of privet plants is not enough. For a long time, the parts of the privet plant we have studied have not been fully utilized, basically not used as medicine, and there is a lot of waste.

[0004] Ursolic acid is a triterpenoid compound with the molecular formula C 30 h 18 o ...