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Zedoary oil product of virus safe medicine and its preparing method

A technology of curcuma oil and antiviral drugs, which is applied in the direction of antiviral agents, pharmaceutical formulas, medical preparations containing active ingredients, etc., can solve the problems of long injection time, no tablets, single curcuma oil, etc., and achieve preparation Low cost, no toxic side effects, pain relief effect

Inactive Publication Date: 2003-07-23
张忠义
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But this medicine only has the single dosage form of the intravenous infusion preparation of zedoary oil at present, does not yet have tablet, capsule, oral sustained-release solid preparation
Intravenous drip preparations take a long time to inject, which is extremely inconvenient to use and brings pain to patients

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] Curcuma oil capsules: Curcuma oil 50g; semi-synthetic fatty acid glycerides 150g; polyethylene glycol 100g; Tween-80 5.0g.

[0030] The preparation method of zedoary oil capsules: 50g of zedoary oil is heated to 100°C, filtered through an 80-mesh sieve, added to 100g of molten polyethylene glycol and 150g of semi-synthetic fatty acid glyceride, and added Tween-80, stirred 20 minutes, make it even, directly pour in the capsule shell at 40 ℃, buckle the cap, obtain the finished product, make 1000 capsules altogether, each capsule contains 50mg of zedoary oil.

Embodiment 2

[0032] Curcuma oil capsules: Curcuma oil 100g; semi-synthetic fatty acid glycerides 200g; polyethylene glycol 200g; Tween-80 10g.

[0033] The preparation method of zedoary oil capsules: 100g of zedoary oil is heated to 100°C, filtered through a 80-mesh sieve, then added to 200g of molten polyethylene glycol and 200g of semi-synthetic fatty acid glycerides, and 10g of Tween-80 is added, Stir for 20 minutes to make it uniform, directly pour it into the capsule shell at 40°C, and buckle the cap to obtain the finished product. A total of 1000 capsules are made, and each capsule contains 100 mg of zedoary oil.

Embodiment 3

[0035] Curcuma oil capsules: Curcuma oil 250g; semi-synthetic fatty acid glycerides 250g; Tween-80 25g.

[0036] The preparation method of zedoary oil capsules is that 250g of zedoary oil is heated to 100°C, filtered through an 80-mesh sieve, then added to 250g of molten semi-synthetic fatty acid glycerides, and 25g of Tween-80 is added, and stirred for 20 minutes to make it Evenly, directly pour in the capsule at 40 ℃, buckle the cap, and obtain the finished product, make 1000 capsules altogether, each capsule contains 250mg of zedoary oil.

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PUM

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Abstract

An antivirus medicine in the form of capsule is prepared from zedoary, oil as primary component, semisynthetic glycerine ester of fatty acid, polyethanediol and surfactant through proportioning, heating zedonary oil to 30-150 deg.c, sieving by 40-100 meshes, mixing with polyethanediol and surfactant, sirring for 30-60 min, and loading in capsule at 10-60 deg.C. Its advantages are high curative effect and no toxic by-effect.

Description

(1) Technical field [0001] The invention relates to an antiviral medicine, in particular to a preparation of the antiviral medicine curcuma oil and a preparation method thereof. (2) Technical background [0002] At present, there are many kinds of antiviral drugs, but the antiviral range of some antiviral drugs is too narrow, only used in dermatology and ophthalmology, such as cytarabine, araclovir, etc.; However, it has a wide range of toxic and side effects, such as ribavirin, which is a broad-spectrum antiviral drug widely used, but it has strong teratogenic and anemic side effects, and large doses can cause heart damage. Therefore, its use is greatly limited. [0003] Curcuma oil is the muddy hair oil extracted from natural Chinese herbal medicine, which belongs to the western preparation of traditional Chinese medicine. This medicine has the characteristics of a wide range of anti-virus, and can quickly reduce the fever of patients with respiratory tract infection, imp...

Claims

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Application Information

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IPC IPC(8): A61P31/12
Inventor 张忠义
Owner 张忠义
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