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Small pellet of Erigeron breviscapus

A technology of breviscapine and dropping pills, applied in the directions of pill delivery, cardiovascular system diseases, organic active ingredients, etc., can solve the problems of inconvenient use and low bioavailability of injections, achieve good antithrombotic effect, and improve bioavailability. degree of pain and hassle-free effect

Inactive Publication Date: 2004-07-21
GUIZHOU XINBANG PHARMACEUTICAL CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Breviscapine is a commonly used effective medicine for the treatment of cardiovascular diseases in traditional medicine in my country. However, tablets and injections are generally used at present. Because it is an insoluble drug, the tablet exists in the form of granules after disintegration. The bioavailability is not high, and the injection is inconvenient to use, so it cannot be used well by patients

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0014] Embodiment of the present invention: taking the production of 1000 capsules as an example, take 4g of breviscapine and add 28g of PEG4000, heat and melt in a water bath, keep warm at 70°C for 10 minutes, and drop into the liquid with a dropper at a rate of 30 drops per minute Collect the dropping pills in paraffin, wash with ethanol to remove the cooling liquid, and dry them to obtain the dropping pills.

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PUM

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Abstract

A dripping pill of breviscapine is prepared from breviscapine and polyethylene glycol (PEG 4000) 5-8 times through conventional process. Its advantages are high curative effect and high biological utilization rate.

Description

Technical field: [0001] The invention relates to a medicine for treating cardiovascular diseases, in particular to a dripping pill for treating cardiovascular diseases. technical background: [0002] Cardiovascular disease is a common disease. With the rapid aging of my country's population, its incidence rate is also increasing. Breviscapine is a commonly used effective medicine for the treatment of cardiovascular diseases in traditional medicine in my country. However, tablets and injections are generally used at present. Because it is an insoluble drug, the tablet exists in the form of granules after disintegration. The bioavailability is not high, and the injection is inconvenient to use, so it cannot be well used by patients. Invention content: [0003] The purpose of the present invention is to provide a drop pill made of scutellarin, which can greatly improve the dissolution and absorption of the drug and improve the efficacy of the drug, so as to solve the above p...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/20A61K31/7048A61P9/00A61P9/10
Inventor 张观福吕玉涛
Owner GUIZHOU XINBANG PHARMACEUTICAL CO LTD
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