Therapeutic compositions

Abstract

Compositions comprising ketone bodies and / or their metabolic precursors are provided that are suitable for administration to humans and animals and which have the properties of, inter alia, (i) increasing cardiac efficiency, particularly efficiency in use of glucose, (ii) for providing energy source, particularly in diabetes and insulin resistant states and (iii) treating disorders caused by damage to brain cells, particularly by retarding or preventing brain damage in memory associated brain areas such as found in Alzheimer's and similar conditions.These compositions may be taken as nutritional aids, for example for athletes, or for the treatment of medical conditions, particularly those associated with poor cardiac efficiency, insulin resistance and neuronal damage. The invention further provides methods of treatment and novel esters and polymers for inclusion in the compositions of the invention.

Description

therapeutic composition This application is a divisional application of a Chinese patent application with a priority date of March 17, 1997, an application date of March 17, 1998, and application number 98805163.X. technical field The present invention relates to compositions suitable for administration to humans and animals, characterized in particular by (i) enhancing cardiac performance, especially the efficiency with which the heart utilizes glucose, (ii) providing energy, especially in diabetes and insulin resistance (iii) treating conditions caused by damage to brain cells, especially by delaying or preventing brain damage in areas of the brain associated with memory, such as in the brain in Alzheimer's disease and similar conditions Find the brain damage, to achieve the therapeutic effect. These compositions can be used as nutritional supplements, for example for athletes, or for the treatment of diseases, especially those related to cardiac insufficiency, insulin re...

AI Technical Summary

Problems solved by technology

Fourth, the consumption of large amounts of lipid substances in adults can lead to severe hypertriglyceridemia, the pathological consequence of which is an increased risk of vascular disease, sporadic liver disease, and pancreatic disease, so lipids cannot be prescribed in the medical field use

It was found to be non-toxic and reduced the concentration of glucose free fatty acids and glycerol, but had no effect on reducing the oxidation of leucine

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