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Extractive of Chinese traditional medicine prepared from epimedium and drynaria, and method for producing preparation

A technology of extract, Drynariae, applied in the direction of drug combination, pharmaceutical formula, bone disease, etc.

Inactive Publication Date: 2005-08-31
JIANMIN PHARMA GRP CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there is no preparation composed of two traditional Chinese medicines, which is effective in treating osteoporosis, so this medicine was invented.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] Example 1 Preparation of Capsules

[0027] Epimedium Extract 10g

[0028] Drynaria Extract 2.5g

[0029] Starch 3g

[0030] Dextrin 1.5g

[0031] Magnesium stearate 0.1g

[0032] Medicinal alcohol 2-3ml

Embodiment 2

[0033] Example 2 Preparation of common tablets and coating

[0034] Epimedium Extract 10g

[0035] Drynaria Extract 2.5g

[0036] Crystalline Cellulose 8g

[0037] Sodium starch 2g

[0038] Starch 3g

[0039] Magnesium stearate 0.2g

[0040] Coating powder 1g

Embodiment 3

[0041] Example 3 Preparation of Dispersible Tablets

[0042] Epimedium Extract 10g

[0043] Drynaria Extract 2.5g

[0044] Crystalline Cellulose 8g

[0045] Sodium starch 2g

[0046] Polyvinylpyrrolidone 1g

[0047] Micronized silica gel 0.5g

[0048] Medicinal ethanol 3ml

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PUM

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Abstract

A Chinese medicine for treating primary osteoporosis and climacteric syndrome is prepared from epimedium and fortune's drynaria rhizome through extracting in alcohol solution, macroreticular resin separation or extracting by ethyl acetate, and refining.

Description

[0001] The present invention relates to the preparation method of the extract from Epimedium and Rhizoma Drynaria and the preparation thereof, wherein the extracts from Epimedium and Drynaria are prepared by separate extraction or combined extraction. A mixed drug for treating osteoporosis obtained by extracting water-containing alcohol or ethyl acetate, the purpose of which is to provide a drug with high content of active ingredients, low toxicity, small dosage and convenient use, which is used for osteoporosis and menopausal syndrome product. [0002] The medicine of the invention consists of epimedium and drynaria total flavonoids as main effective parts. The extract mainly contains the total flavonoids extracted from the above two Chinese herbal medicines, and its content is between 50% and 95%. Background of the invention [0003] Osteoporosis is a systemic skeletal disease characterized by decreased bone mass and degeneration of bone microstr...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61P9/10A61P15/12A61P19/10
Inventor 熊富良黄志军李崇明曾庆恢徐绍新刘健伟朱立彬
Owner JIANMIN PHARMA GRP CO LTD