Dripping pill for treating coronary heart disease and preparing method

A technology of dropping pills and Cortex Moutan is applied in the field of dropping pills and pills for treating coronary heart disease and angina pectoris. therapeutic effect

Active Publication Date: 2006-03-08
BEIJING ASIA EAST BIO PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The aerosol has the effects of clearing away heat and cooling blood, promoting blood circulation and relieving pain. It has a certain effect on mild to moderate chest pain, pain and restlessness, yellow tongue coating and other symptoms of partial heat type. However, the aerosol has the following defects at the same time: The accuracy of the dosage is not high, and there are many interference factors in the lung absorption when the drug is inhaled, so the absorption is incomplete and the variability is large; a pressure-resistant device and a valve system are required, and the cost is high

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0015] The raw materials were weighed according to the following weights: 20.1 g of cortex Moutan, 33.6 g of Rhizoma Chuanxiong, and 2.18 g of borneol. The above three flavors, Cortex Moutan are crushed into coarse powder, according to the percolation method (Appendix I of "Chinese Pharmacopoeia" 2000 edition) under the liquid extract and extract item, use 90% ethanol as solvent, cold soak for 24 hours, slowly Percolation, collecting the percolation liquid, and recovering ethanol. Crush Rhizoma Chuanxiong into pieces, add water to extract the volatile oil for 2 hours, pour out the distilled aqueous solution, decoct the dregs with water for 1 hour, filter, combine the filtrate with the above aqueous solution, and concentrate it into a clear liquid with a relative density of 1.20-1.25 (70°C). paste, add ethanol to make the alcohol content 50%, stir, let stand for 24 hours, absorb the supernatant, and reclaim the ethanol. Combine Moutan cortex and Chuanxiong medicinal liquid, co...

Embodiment 2

[0017] The raw materials were weighed according to the following weights: 20.1 g of cortex Moutan, 33.6 g of Rhizoma Chuanxiong, and 2.18 g of borneol. The above three flavors, Cortex Moutan are crushed into coarse powder, according to the percolation method (Appendix I of "Chinese Pharmacopoeia" 2000 edition) under the liquid extract and extract item, use 90% ethanol as solvent, cold soak for 24 hours, slowly Percolation, collecting the percolation liquid, and recovering ethanol. Crush Rhizoma Chuanxiong into pieces, add water to extract the volatile oil for 2 hours, pour out the distilled aqueous solution, decoct the dregs with water for 1 hour, filter, combine the filtrate with the above aqueous solution, and concentrate it into a clear liquid with a relative density of 1.20-1.25 (70°C). paste, add ethanol to make the alcohol content 50%, stir, let stand for 24 hours, absorb the supernatant, and reclaim the ethanol. Combine Moutan cortex and Chuanxiong medicinal liquid, co...

Embodiment 3

[0019] The raw materials were weighed according to the following weights: 20.1 g of cortex Moutan, 33.6 g of Rhizoma Chuanxiong, and 2.18 g of borneol. The above three flavors, Cortex Moutan are crushed into coarse powder, according to the percolation method (Appendix I of "Chinese Pharmacopoeia" 2000 edition) under the liquid extract and extract item, use 90% ethanol as solvent, cold soak for 24 hours, slowly Percolation, collecting the percolation liquid, and recovering ethanol. Crush Rhizoma Chuanxiong into pieces, add water to extract the volatile oil for 2 hours, pour out the distilled aqueous solution, decoct the dregs with water for 1 hour, filter, combine the filtrate with the above aqueous solution, and concentrate it into a clear liquid with a relative density of 1.20-1.25 (70°C). paste, add ethanol to make the alcohol content 50%, stir, let stand for 24 hours, absorb the supernatant, and reclaim the ethanol. Combine Moutan cortex and Chuanxiong medicinal liquid, co...

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PUM

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Abstract

The present invention discloses a kind of dripping pills preparation for effectively curing coronary heart disease and angina pectoris. Said dripping pills preparation is made up by using Chinese medicinal materials of tree peony bark, ligusticum root and borneol through a certain preparation process. Said invention also provides the concrete steps of said preparation process.

Description

technical field [0001] The invention relates to a drop pill, in particular to a drop pill for treating angina pectoris of coronary heart disease prepared by taking moutan cortex, chuanxiong and borneol as raw materials, and belongs to the field of traditional Chinese medicine preparations. Background technique [0002] The quick-acting heartache aerosol is prepared from Moutan Cortex 240g, Chuanxiong 401g, and Borneol 26g according to the following method: the above three flavors, Moutan Cortex and Chuanxiong Rhizoma are respectively crushed into coarse powder; Use 5300ml of 90% ethanol, stir for 6 hours, let stand for 12 hours, use 4000ml of 90% ethanol for the second time, stir for 4 hours, let stand for 12 hours, absorb the supernatant, filter, and recover the ethanol to a volume of about 500ml. Extract volatile oil from Rhizoma Chuanxiong, filter the distilled aqueous solution, concentrate under reduced pressure to a clear paste (about 120g), add an equal amount of ethan...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/71A61K36/23A61K9/20A61P9/10
Inventor 付建家
Owner BEIJING ASIA EAST BIO PHARMA CO LTD
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