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Traditional Chinese medicine effective part for treating influenza virus and its preparation process

A technology for anti-influenza virus and effective parts, applied in antiviral agents, medical preparations containing active ingredients, and pharmaceutical formulas, etc., can solve problems such as backward drug production technology, damage to heat-sensitive active ingredients, and affecting the efficacy of traditional Chinese medicine.

Active Publication Date: 2006-10-04
GUANGZHOU XINGQUN PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, because the raw material medicine is usually extracted with water, only water-soluble components are obtained, which affects the efficacy of traditional Chinese medicine; there is a long-term heating in the process, which leads to the destruction of heat-sensitive active ingredients, and cannot be used as a first-line drug for anti-epidemic Influenza; At the same time, due to the backward production technology of the drug, insufficient scientific and technological content, and rough dosage forms, it is difficult for consumers to accept

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] Embodiment 1: get 100 parts of Prunella vulgaris, 35 parts of mulberry leaves, 16 parts of wild chrysanthemums, the total weight of medicinal materials is 453g, pulverize into 10-30 mesh powder, put in a supercritical extraction device, use CO 2 Carry out supercritical extraction, extraction condition is: extraction pressure 21Mpa; Extraction temperature is 50 ℃, analysis pressure 6.5Mpa; Analysis temperature is 45 ℃, extracts for 3 hours, obtains the extract 25g that contains fat-soluble effective part, adds appropriate auxiliary material, prepares Formed into soft capsules containing 0.1g / capsule supercritical extract, used to prevent bird flu, 3 times a day, one capsule at a time, for 3 consecutive days.

Embodiment 2

[0030] Embodiment 2: get 5 parts of Prunella vulgaris, 20 parts of mulberry leaves, 100 parts of wild chrysanthemums, the total weight of medicinal materials is 250g, pulverize into 30 mesh powder, put in a supercritical extraction device, use CO 2 Carry out supercritical extraction, the extraction condition is: extraction pressure 16Mpa; Extraction temperature is 35 ℃, analysis pressure 5Mpa; Analysis temperature is 30 ℃, extracts for 2 hours, obtains the extract containing fat-soluble effective part 14g, adds appropriate amount of auxiliary material, is made Drops containing supercritical extract for the prevention of avian influenza in poultry.

Embodiment 3

[0031] Embodiment 3: get 200 parts of Prunella vulgaris, 100 parts of mulberry leaves, 10 parts of wild chrysanthemums, the total weight of medicinal materials is 620g, pulverize into 20 mesh powder, put in a supercritical extraction device, use CO 2 Carry out supercritical extraction, the extraction condition is: extraction pressure 33Mpa; Extraction temperature is 50 ℃, analysis pressure 9Mpa; Analysis temperature is 55 ℃, extracts for 4 hours, obtains the extract containing fat-soluble effective part 35g, adds appropriate amount of auxiliary material, is prepared The emulsion containing 2% supercritical extract is used for spraying disinfection and epidemic prevention during the outbreak of bird flu.

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Abstract

The invention discloses an effective portion of traditional Chinese medicament for resisting influenza virus, which is prepared from selfheal 5-200 parts, mulberry leaf 5-1-00 parts, wild chrysanthemum flower 5-100 parts as raw material through disintegrating, and supercritical CO2 extraction. The effective portion can be prepared into tablets, capsules, granules, oral liquids, injections, inhalants, sprays or drop pills.

Description

technical field [0001] The invention relates to a compound preparation drug, in particular to a traditional Chinese medicine preparation for treating influenza virus and a preparation method thereof. Background technique [0002] Chinese medicine has a unique curative effect on the treatment of influenza. "Xia Sangju" is composed of three traditional Chinese medicines of Prunella vulgaris, mulberry leaves and wild chrysanthemum. The "Xia Sangju granule" made by water extraction is a famous Chinese patent medicine in my country. It is often used in the treatment of fever in traditional Chinese medicine. It is often used as herbal tea to fight against influenza in daily life. . However, because the raw material medicine is usually extracted with water, only water-soluble components are obtained, which affects the efficacy of traditional Chinese medicine; there is a long-term heating in the process, which leads to the destruction of heat-sensitive active ingredients, and cannot...

Claims

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Application Information

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IPC IPC(8): A61K36/60A61K9/08A61K9/10A61K9/12A61K9/16A61K9/20A61K9/48A61K9/72A61P31/16
Inventor 詹华强董婷霞
Owner GUANGZHOU XINGQUN PHARMA
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