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Pharmaceutical and cosmetic formulations for treating fingernails

A nail, topical application technology, used in pharmaceutical formulations, medical preparations with inactive ingredients, manicures, etc.

Inactive Publication Date: 2006-10-04
BIOEQUAL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] To date there are no satisfactory products for topical treatment of nail disorders and topical nail care which contain a carrier for delivering the required amount of active substance through the nail into the nail root (matrix) for successful treatment. necessary

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0077] Embodiment 1: Clotrimazole (Clotrimazole) solution 1%

[0078] Clotrimazole 1.0g

[0079] 1-Hexanol 100.0ml

[0080] Under stirring, clotrimazole was dissolved in 100 ml of 1-hexanol.

Embodiment 2

[0081] Embodiment 2: Amorolfine (Amorolfine) solution 1%

[0082] Amorolfine 1.0g

[0083] Ethanol 1.0g

[0084] 1-Hexanol 60.0g

[0085] 1-heptanol 28.0g

[0086] Amorolfine was stirred in the ethanol, 1-hexanol, 1-heptanol mixture until a homogeneous solution was obtained.

Embodiment 3

[0087] Embodiment 3: Australian blue cypress oil, tea tree oil and lavender oil solution 6%

[0088] Australian Blue Cypress Oil 2.0g

[0089] Tea tree oil 2.0g

[0090] Lavender Oil 2.0g

[0091] Isoamyl acetate 94.0g

[0092] The mixture was stirred until a homogeneous solution was obtained.

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PUM

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Abstract

The invention relates to topical agents used for treating nail diseases and nail care containing besides one or several active substances and possibly adjuvants and solubilisation physiologically tolerable agents, one or several compounds of formula (I): R-O-R1, wherein R is a linear or branched alkyl group comprising 5-8 carbon atoms and R1 is hydrogen, a formula or acetyl group. The inventive agents are also appropriate for veterinary medicine for treating fungal infections of hooves and nails of domestic and working animals.

Description

technical field [0001] The present invention relates to topical products for the treatment of nail disorders and nail care, having improved permeability through the nail substance and the skin. Background technique [0002] In practice, direct topical treatment of nail diseases and nail care is simple and minimally costly without side effects. However, a major challenge with the direct topical application of nail compositions is to deliver sufficient amounts of active substances, including nutrients and anabolic substances, through the nail into the deeper tissue layers and into the root of the nail to completely destroy the pathogens present and provide the nail with Nutrients and anabolic substances. Traditional products have the potential to relieve symptoms with direct topical treatment; however, in most cases, symptoms recur after treatment is stopped. [0003] Direct topical application of active substances has been proposed to improve therapeutic results, wherein th...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/37A61Q3/00A61K47/10A61K47/14A61K8/34A61K8/44A61K8/49A61K8/67A61K8/97A61K9/00
CPCA61K47/10A61K8/97A61K8/44A61K8/34A61K9/0014A61Q3/00A61K8/67A61K8/342A61K8/447A61K8/37A61K47/14A61K8/4913A61K8/9789A61P17/00A61P31/04A61P31/10A61K8/49
Inventor 汉斯·梅尔
Owner BIOEQUAL
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