Medical fluid, a method of treatment and use of the fluid

Abstract

A medical fluid for a harvested organ, tissue or parts thereof, for evaluation and / or preservation. The fluid includes cocaine or a stimulating analogue thereof; nor-adrenalin; and / or adrenaline. In addition, the fluid includes an oncotic agent, such as dextran; hormones, such as thyroxin; triiodotyronine; cortisone, insulin; and electrolytes and optionally nutrients in substantially physiological concentrations in a physiologically acceptable medium. In addition, the medical fluid further includes albumin in a concentration not exceeding 5.0%, and an oxygen carrier, such as erythrocytes. Further components may be dopamine; hydrocortisone; methylprednisolone; and a vasopressor agent, such as desmopressin. The cocaine; adrenalin; and noradrenaline are present in concentrations of each about 0.010 μM to 0.100 μM, for example in a ratio of 1:1:1.

Description

FIELD OF INVENTION[0001]The present invention relates to a method of handling an organ after harvesting, including a medical fluid and use of said fluid.BACKGROUND OF THE INVENTION[0002]It is well known that there is a great shortage of donor organs, which may be used for transplantation.[0003]After harvesting, the organs should be examined and evaluated for viability to be used for transplantation purpose. The evaluation may be performed at a physiological temperature of about 37° C., such as between 30° C. and 40° C., or alternatively at a lower temperature. During the evaluation, the organs may be perfused by and / or surrounded by an evaluation fluid similar to blood.[0004]Normally, the organs cannot be transplanted immediately, but a recipient should be found, which may take some time. Moreover, the organ to be transplanted should be transported to the recipient or the recipient be transported to the organ. Thus, the organs may be preserved for some hours or days, often at hypoth...

AI Technical Summary

Benefits of technology

[0010]Accordingly, an object of the present invention is to mitigate, alleviate or eliminate one or more of the above-identified deficiencies and disadvantages singly or in any combination.

Problems solved by technology

It is well known that there is a great shortage of donor organs, which may be used for transplantation.

Normally, the organs cannot be transplanted immediately, but a recipient should be found, which may take some time.

Such medical fluids involve compromises between cost and performance.

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