Method for modifying THC content in a lipid-based extract of cannabis

a technology of lipid-based extracts and cannabinoids, which is applied in the direction of non-active ingredients, biocide, oil/fat/waxes, etc., can solve the problems of reducing yield, reducing psychoactivity, and reducing the therapeutic effect of isolated cannabinoids, so as to reduce psychoactivity, improve production efficiency, and reduce the effect of th

Active Publication Date: 2016-02-16
RADERMAN HLDG LLC
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

[0016]The present invention includes a novel extraction process that yields a formulated cannabinoid nutraceutical. Preferably the extraction process is applied to hemp, lowers the THC as a percentage of the cannabinoid mix, reduces psychoactivity, and meets regulatory requirements of hemp products. Various methods of the present invention are designed to be performed in a food-grade manufacturing environment and do not require laboratory conditions using vacuum distillation or gas chromatography. This vastly improves production efficiency while reducing equipment costs.
[0024]The step of vaporizing is preferably accomplished at ambient pressure, i.e. 1 atm of pressure, without the need for a vacuum. This enables cost-effective scaling of the process using standard food processing equipment to create a cannabis product.
[0039]It can be appreciated that a product using the present methods can achieve a high CBN:THC ratio, much higher than found in the substrate material used. The CBD:THC ratio is also selectively maximized.

Problems solved by technology

One drawback of the Kottayil et al. invention is that isolated cannabinoids do not always achieve the therapeutic functionality as well as a whole plant extract containing a range of cannabinoids.
This legal limit can be met by harvesting the hemp plants prior to maturity, which has the benefit of a reduced THC content, but the drawback of reducing yield.
This has the benefit of improving per-plant yield of CBD, but the drawback of additional regulation.
However this is a tedious and expensive process.

Method used

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  • Method for modifying THC content in a lipid-based extract of cannabis
  • Method for modifying THC content in a lipid-based extract of cannabis
  • Method for modifying THC content in a lipid-based extract of cannabis

Examples

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example 1

[0082]Mix 1600 grams of dried cannabis substrate (leaves and flowers), ½ gallon of coconut oil, and 4 gallons of water. This yields an approximate ratio of 1:8 lipid oil to water. This ratio produces a concentration of no less than 25 mg of nearly full spectrum extracted cannabinoids per 1 ML of coconut oil. The final extracted oil can then be encapsulated, and taken internally, or applied topically. A capsule could be made of gelatin, plant cellulose, or combined with starch into a pressed pill.

[0083]Stage 1:[0084]A. Mix 1600 grams of dried cannabis, ½ gallon of coconut oil, and 4 gallons of water is added to the pressure cooker. Heat under pressure at 15 psi at 121° C. degrees for 6 hours.[0085]B. Reduce heat and pressure to 7 psi above atmospheric at 107° C. for an additional 14 hours.[0086]C. The vessel is brought down to atmospheric pressure at 93° C.[0087]D. Saturated substrate is then squeezed of all liquid using mechanical pressure.[0088]E. All liquid is saved and put in a s...

example 2

Post Processing to Decarboxilate and Reduce THC

[0129]A. After STAGE 3 is complete and the coconut oil congeals and separates from the water, place congealed coconut oil in a clean stainless steel pot. Heat oil rapidly to above 141° C., preferably above the vaporization temperature of THC i.e. 157° C. and below the vaporization temperature of CBD, which is between 160-180° C. This process will remove any remaining water content in the oil and volatilize a portion of THC contained in the concentrated cannabis product.[0130]B. Continue heating the oil at 121° C. for an additional 10 min to activate cannabinoids, causing most of any remaining non-decarboxilated portion of the cannabinoids to decarboxilate.[0131]C. Allow the oil to cool to 82° C. and pour through a filter no greater than 20 microns.[0132]D. The oil should be nearly 100% water free and most cannabinoids will be decarboxilated. Concentration of cannabinoids in the cannabinoid product is preferably no less than 25 mg of can...

example 3

Post Processing to Increase CBD:THC Ratio

[0134]A. After STAGE 3 is complete and all oil separated, place congealed coconut oil in a clean stainless steel pot. Heat oil rapidly to above 141° C., preferably above the vaporization temperature of THC i.e. 157° C. and below the vaporization temperature of CBD, which is between 160-180° C. This process will remove the remaining water content in the oil and some THC content will be volatilized. Although some CBD may be volatilized, preferably the cannabis substrate used in the various extraction stages is from a hemp strain containing at least a 8:1 ratio of CBD:THC so even with some degradation of CBD, there is a significant residual amount of CBD in the cannabinoid mix[0135]B. Continue heating the oil at 132° C. for an additional 10 min to convert a portion of THC to CBN.[0136]C. Allow the oil to cool to 82° C. and pour through a filter no greater than 20 microns.[0137]D. The oil should be 100% water free and most cannabinoids will be de...

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Abstract

A method for modifying THC content in a lipid-based extract of cannabis to yield a low-THC product. The method includes providing a lipid-based extract of cannabis containing THC, heating the lipid-based extract at 1 atm of pressure to 157 to 160° C. to vaporize a first portion of the THC, and converting a second portion of the THC to CBN by heating the lipid-based extract to between 130° C.-150° C. for at least 10 min.

Description

PRIORITY CLAIM[0001]This patent application claims priority to U.S. Provisional Patent Application Ser. No. 61 / 964,538, filed 7 Jan. 2014, the disclosure of which is incorporated herein by reference.FIELD OF THE INVENTION[0002]This invention relates to ways of extracting and concentrating cannabinoids from plant substrates including hemp, and particularly ways of modifying ratios of various cannabinoids including trans-Δ9-tetrahydrocannabinol (THC), Cannabinol (CBN) and Cannabidiol (CBD).BACKGROUND OF THE INVENTION[0003]U.S. Patent Publication No. US 2006 / 0160888 A1 to Kottayil et al. describes a Dronabinol formulation that is shelf stable and FDA approved. This is a pharmaceutical drug prescribed for anti-nausea in chemotherapy patients. The cannabinoid solution is in an oil-based carrier mixture having stabilizing amount of one or more anti-oxidants and other organic bases. The oil used is may include coconut oil in one embodiment. The formulation can be packaged in a soft gelatin...

Claims

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Application Information

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Patent Type & Authority Patents(United States)
IPC IPC(8): A01N65/00A61K47/44A61K31/05A61K36/185A61K9/00
CPCA61K36/185A61K31/05A61K47/44A61K9/0053A61K2236/00A61K9/0014A61K9/48A61K2236/37A61K2236/39A61K2236/53A61K2236/55
Inventor RADERMAN, JOSHUA, MICHAEL
Owner RADERMAN HLDG LLC
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