The invention discloses VR equipment applicable to MRI and a virtual reality interaction method thereof. The VR equipment comprises two lenses, a display screen, a tracking device, three-dimensional stereo sound equipment, a real scene simulation device, a battery and a controller, wherein the two lenses are aligned with the display screen; the battery, the tracking device, the display screen, thethree-dimensional stereo sound equipment, and the real scene simulation device are electrically connected with the controller; a data interface connected with an external computer is arranged on thecontroller; the tracking device, the display screen, the three-dimensional stereo sound equipment, the real scene simulation device and the controller are fixedly connected through an external extrudable material. The fMRI based on a VR creation technology is used; a claustrophobia patient is introduced to generate low-degree fear; the real-time monitoring is performed so as to make a brain functional region nerve electrophysiological path, so that the exploration on the modern VR creation technology is realized; the development technology is reserved for the tumor patient brain function induction study and mental guidance study.