32 results about "Induction therapy" patented technology

An energy emitting apparatus for providing a medical therapy includes one or more energy generators, a logic controller electrically connected to the one or more energy generators, and one or more sensors for detecting electric conduction in a target nerve that are connected to the logic controller. The one or more energy generators produce energy focused on the target nerve upon receiving a signal from the logic controller, and the energy is varied by the logic controller according to an input provided by the one or more sensors. In one embodiment, the energy emitting apparatus is an apparatus for magnetic induction therapy that includes one or more conductive coils disposed in an ergonomic housing that produce a magnetic field focused on the target nerve upon receiving an electric current from the logic controller based on an input provided by the one or more sensors.

A device for creating a plurality of small wounds in a patient's skin and introducing topically-applied substances therein is disclosed. The device comprises a rigid plate that has a top side, a bottom side, and at least one peripheral edge that connects the top and bottom sides. The device further includes a tool attachment means fixed with the top side of the plate and adapted to fix the device to a motorized tool that oscillates reciprocally back and forth along the longitudinal axis of the plate. A plurality of needles project generally orthogonally away from the bottom side of the plate. In use, the plate is fixed with the tool and the tool activated. The bottom side of the plate is then applied to the skin of the patient such that each needle repeatedly pierces same to create the plurality of small wounds therein. When the substance is applied to the skin first, each needle draws a portion of the substance into the skin with each oscillation of the tool.

The present invention provides a method of treating a subject afflicted with a form of multiple sclerosis or presenting a clinically isolated syndrome comprising periodic administration of an amount of rituximab at least twice to the subject followed by periodic administration of an amount of glatiramer acetate to the subject, wherein the amounts are effective to treat the subject. The present invention also provides a method of treating a subject afflicted with an immune disease, comprising periodic administration of an amount of rituximab at least twice to the subject followed by periodic administration of an amount of glatiramer acetate to the subject wherein the amounts are effective to treat the subject, and wherein the immune disease is an autoimmune disease, an arthritic condition, a demyelinating disease, an inflammatory disease, multiple sclerosis, relapsing-remitting multiple sclerosis, diabetes mellitus, psoriasis, rheumatoid arthritis, inflammatory bowel disease, Crohn's disease, or systemic lupus erythematosus.

The invention discloses an induction therapy method for epileptic discharge in deep brain of an epileptic and a device thereof, which is of a new medical concept and a new medical device. The therapy method and the device of the invention are used for curing an epileptogenic focus in the deep brain area of the epileptic, particularly for the intractable epileptic by using medicines. The device of the invention comprises a needle-shaped electrode in the brain, a guide wire with an insulating layer, a protection sheath for silica gel guide wires and an electrode plate under the scalp. The method and the device of the invention are characterized in that the induction method is adopted to induce the hypersynchrony discharge of the epileptic under the skin outside the skull, an electrode made by the material with high electrical conductivity is embedded to epileptic discharge parts in the brain and connected to the electrode plate outside the skull by the guide wire that is made by the material with high electrical conductivity and is provided with the outer insulating layer, the electric potential difference between the high voltage in the explosive discharge of the epilepsy and the low voltage outside the skull is utilized to induce the explosive discharge current to the exterior of the brain, thereby avoiding the clinic epileptic seizure formed by the discharge induction of the epilepsy and realizing the aim of curing the epilepsy.

The invention discloses a magnetic induction therapy apparatus comprising a magnetic induction therapy apparatus body and a medical bed. According to the apparatus, magnetic material introduced to a tumor site of a patient is under the action of high-frequency alternating magnetic field, tumor tissue is heated to 60 DEG C-70 DEG C and kept in the required therapeutic temperature range, and tumor cells are killed accordingly. The magnetic induction therapy apparatus has the advantages that under the action of in-vitro alternating magnetic field, the magnetic material planted into the tumor tissue cuts alternating lines of magnetic force to produce alternating current, the magnetic material heats up by the aid of the eddy current, and the tumor tissue is heated.

A pharmaceutical composition for induction therapy which has a hypomethylating agent and a histone deacetylase inhibitor (“HDAC inhibitor”); wherein the hypomethylating agent is a DNA and histone methylation inhibitor such as cladribine and the HDAC inhibitor is, for example, entinostat, panobinostat, vorinostat, and/or romedepsin; further wherein the hypomethylating agent and the HDAC inhibitor are combined in formulations for various administrations including e.g., a continuous delivery system such as a transdermal patch of at least one reservoir or a plurality of reservoirs, oral, a fixed-dose oral combination, intravenous, and combinations thereof. This pharmaceutical composition for induction therapy is used with a monoclonal antibody in the treatment of various cancers, sarcomas, and other malignancies.

The invention relates to a movable neurosurgery operation therapy apparatus, and belongs to the technical field of medical equipment. The movable neurosurgery operation therapy apparatus comprises a therapy apparatus main body, an apparatus carrying board is disposed under the main body, an operation therapy apparatus cabinet is disposed in the front of the therapy device, a therapy apparatus control platform is disposed on the therapy apparatus main body, and a multifunctional auxiliary tank is disposed at the right side of the main body. An induction therapy pipe is disposed in a neurosurgery operation therapy helmet, a head fixing groove disposed in the right side of the induction therapy pipe, a fixing elastic belt is disposed under the head fixing groove, a therapy roller is disposed under the fixing elastic belt, and the left side of the therapy roller is provided with a roller entrance/exit. The movable neurosurgery operation therapy apparatus is comprehensive in function, convenient to use, scientific, convenient, safe, high in efficiency, intelligent and accurate, doctors can easily perform the neurosurgery operation with less time, so the doctors' work efficiency can be reduced.

The present invention relates to methods and medicarnents useful for treating locally advanced pancreatic cancer (LAPC). Improved therapeutic methods and regimens comprising anti-connective tissue growth factor (CTGF) agents, including anti-CTGF antibodies, are provided. Included are induction therapies for converting unreseetable LAPC into borderline or resectable status.

The invention discloses a magnetic induction massage chair which comprises a chair back and a chair body. Magnetic induction acupoint massage blocks are installed on the chair back, cervical vertebra massage wheel shaft holes are formed in the upper end of the chair back, cervical vertebra massage magnetic induction wheels are arranged on a rotating shaft installed at the cervical vertebra massage wheel shaft holes, a motor belt groove is formed in the rotating shaft installed at the cervical vertebra massage wheel shaft holes, a triangular belt is arranged on the motor belt groove, and one end of the triangular belt is arranged on the motor belt groove in a sleeving mode. According to the magnetic induction massage chair, cervical vertebra is massaged through the cervical vertebra massage magnetic induction wheels, the speed can be adjusted according to feelings and requirements till a person feels comfortable, a swing plate drives the person to shake left and right, and meanwhile thigh massage wheels start to rotate, the roots of thighs are pushed and massaged, and magnetic induction therapy is achieved; the magnetic induction acupoint massage blocks at the back are used for conducting magnetic induction therapy by massaging acupoints such as the Shenshu acupoint when the human body shakes along with the swing plate, and the magnetic induction massage chair has the advantage of being good in magnetic induction therapy and massage effect.

It is intended to provide a novel instrument for inducing a cytokine and a method of inducing a cytokine by which a cytokine can be effectively induced compared to the existing cytokine induction therapy. Namely, an instrument for inducing a cytokine which contains a hemolytic streptococcus and/or a hemolytic streptococcus-origin component and a water-insoluble carrier; and a method of inducing a cytokine by using this instrument for inducing a cytokine.

Provided are methods of treating urothelial carcinomas of the lower tract comprising administering comprising administering gemcitabine continuously and locally to the bladder of an individual in an induction therapy and/or maintenance therapy.

A cytokine-inducing material and a cytokine-inducing instrument to be used in cytokine-induction therapy and the like. More specifically speaking, a cytokine-inducing material characterized by containing a water-insoluble induction potentiator comprising a cytokine-inducer such as BCG, a polymer, etc.; and a cytokine-inducing instrument having this inducing material packed in a container. By bringing the inducing material into contact with, for example, blood or blood components, cytokine can be induced more effectively than conventional cases.

An automatic adjusting system based on a human body structure of a magnetic induction therapy instrument comprises an electromagnetic vibration unit, a control unit and a stand column, wherein the electromagnetic vibration unit is arranged below the stand column, and the control unit is arranged above the stand column and is in electric connection with the electromagnetic vibration unit. The control unit comprises a tablet computer, a waveform amplifier and a power amplifier. The tablet computer is used for transmitting wave amplitude control signals to the waveform amplifier. The waveform amplifier produces sine wave signals of set frequency and amplitude of wave amplitude control signals according to the wave amplitude control signals and transmits the wave amplitude control signals to the power amplifier. The power amplifier amplifies the sine wave signals and uses the sine wave signals to drive the electromagnetic vibration unit. The automatic adjusting system based on the human body structure of the magnetic induction therapy instrument has the advantages of being convenient to use and simple in structure.

The present invention relates to the field of therapeutic proteins, in particular, to recombinant coagulation factors. It provides a recombinant Factor VIII (FVIII) protein comprising specific point mutations at defined positions, which serve to reduce the immunogenicity of said FVIII protein, wherein the Factor VIII protein substantially retains its coagulant activity. The invention further provides nucleic acids encoding said de-immunized protein, cell lines and methods of recombinant preparation as well as pharmaceutical compositions comprising the recombinant FVIII of the invention, whichare advantageous for use in treatment of patients with Hemophilia A, particularly those who have not yet been treated with a FVIII product. Additionally, it can be a safe alternative for previously treated patients and even for patients who have developed an immune-response to FVIII, e.g., for immune-tolerance-induction therapy (ITI/ITT) or rescue ITI. The invention also provides an assay for determining immunogenicity of a protein.

This invention provides a method of treating a subject afflicted with multiple sclerosis (MS) or presenting clinically isolated syndrome (CIS) which comprises a) administering to the subject an amount of an anti-CD52 antibody, followed by b) periodically administering to the subject an amount of laquinimod. This invention also provides packages comprising pharmaceutical compositions of laquinimod or an anti-CD52 antibody for treating such a subject wherein laquinimod is to be administered as a maintenance therapy in such a subject who has received an anti-CD52 antibody induction therapy.

The invention relates to a multifunctional body building, exercising, sitting and stepping device which is formed by combining five-element materials with a keep-fit massage function, and a combination mode is based on the principle of mutual generation among wood, fire, earth, metal and water in the traditional Chinese medicine five-element theory. In the device, raised or non-raised five-element particles are fixed in an inlaying, pasting or sewing manner at most major positions such as a center line, double fisheyes and an exterior ring, thus a user can enjoy health care functions such as far infrared therapy, magnetotherapy, microelement importing and the like while performing body building and exercises, and also can enjoy a massage effect of digital pressing of acupuncture points or a comfortable effect based on percutaneous induction therapy.

The present invention is related to peptides that can be used to reduce the immune response against FVIII or to induce tolerance to human FVIII in patients with, e.g., hemophilia A. Furthermore, the peptides can be used for immunodiagnostic purposes to detect FVIII-specific CD4+ T cells to monitor patients with hemophilia A during replacement therapy and during immune tolerance induction therapy.